Mutations in the M-Gene Segment Can Substantially Increase Replication Efficiency of NS1 Deletion Influenza A Virus in MDCK Cells

Attenuated Influenza Virus Construct with Enhanced Hemagglutinin Protein Expression

(2012) J. Maamary et al.   JOURNAL OF VIROLOGY

Suppression of the antiviral response by an influenza histone mimic

(2012) Ivan Marazzi et al.   NATURE

Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets

(2012) S. Herfst et al.   SCIENCE

Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host response

(2011) Claudius Seitz et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The accumulation of influenza A virus segment 7 spliced mRNAs is regulated by the NS1 protein

(2011) N. C. Robb et al.   JOURNAL OF GENERAL VIROLOGY

Genomic and Protein Structural Maps of Adaptive Evolution of Human Influenza A Virus to Increased Virulence in the Mouse

(2011) Jihui Ping et al.   PLoS One

Adaptation of High-Growth Influenza H5N1 Vaccine Virus in Vero Cells: Implications for Pandemic Preparedness

(2011) Yu-Fen Tseng et al.   PLoS One

Impact of Host Cell Line Adaptation on Quasispecies Composition and Glycosylation of Influenza A Virus Hemagglutinin

(2011) Jana Verena Roedig et al.   PLoS One

MDCK cell line with inducible allele B NS1 expression propagates delNS1 influenza virus to high titres

(2011) R. van Wielink et al.   VACCINE

Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral

(2011) Charles E. Samuel   VIROLOGY

Inefficient splicing of segment 7 and 8 mRNAs is an inherent property of influenza virus A/Brevig Mission/1918/1 (H1N1) that causes elevated expression of NS1 protein

(2011) Ellenor Backström Winquist et al.   VIROLOGY

High yields of influenza A virus in Madin-Darby canine kidney cells are promoted by an insufficient interferon-induced antiviral state

(2010) C. Seitz et al.   JOURNAL OF GENERAL VIROLOGY

Adaptation of a Madin–Darby canine kidney cell line to suspension growth in serum-free media and comparison of its ability to produce avian influenza virus to Vero and BHK21 cell lines

(2010) R. van Wielink et al.   JOURNAL OF VIROLOGICAL METHODS

NS Reassortment of an H7-Type Highly Pathogenic Avian Influenza Virus Affects Its Propagation by Altering the Regulation of Viral RNA Production and Antiviral Host Response

(2010) Z. Wang et al.   JOURNAL OF VIROLOGY

Double-Stranded RNA Adenosine Deaminase ADAR-1-Induced Hypermutated Genomes among Inactivated Seasonal Influenza and Live Attenuated Measles Virus Vaccines

(2010) R. Suspene et al.   JOURNAL OF VIROLOGY

Establishment of a Chimeric, Replication-Deficient Influenza A Virus Vector by Modulation of Splicing Efficiency

(2010) M. Wolschek et al.   JOURNAL OF VIROLOGY

Structure-based design of NS2 mutants for attenuated influenza A virus vaccines

(2010) Hatice Akarsu et al.   VIRUS RESEARCH

NS2/NEP protein regulates transcription and replication of the influenza virus RNA genome

(2009) Nicole C. Robb et al.   JOURNAL OF GENERAL VIROLOGY

A Novel Type of Influenza Vaccine: Safety and Immunogenicity of Replication‐Deficient Influenza Virus Created by Deletion of the Interferon Antagonist NS1

(2009) Volker Wacheck et al.   JOURNAL OF INFECTIOUS DISEASES

Preclinical Evaluation of a Replication-Deficient Intranasal ΔNS1 H5N1 Influenza Vaccine

(2009) Julia Romanova et al.   PLoS One

Development of a live-attenuated influenza B ΔNS1 intranasal vaccine candidate

(2009) Nina Wressnigg et al.   VACCINE

The multifunctional NS1 protein of influenza A viruses

(2008) B. G. Hale et al.   JOURNAL OF GENERAL VIROLOGY