Journal
JOURNAL OF VIROLOGY
Volume 86, Issue 11, Pages 6381-6382Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.00710-12
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Funding
- National Scientific and Technical Supporting Programs [2006BAD06A07, 2008FY130100-2, 2009BADB4B05-3]
- Scientific Achievement Transformation Program [2009GB23260435]
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JXA1-P170 is an overattenuated highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) that has been passaged in vitro 170 times. Vaccination with JXA1-P170 cannot protect pigs against JXA1 challenge. Compared with the parental virus JXA1, JXA1-P170 contains 1 nucleotide (nt) deletion and 113 nt mutations leading to 59 amino acid substitutions. Here we announce the first complete genome sequence of the overattenuated HP-PRRSV.
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