Hepatitis C Virus NS5A Disrupts STAT1 Phosphorylation and Suppresses Type I Interferon Signaling

Distinct Functions of NS5A in Hepatitis C Virus RNA Replication Uncovered by Studies with the NS5A Inhibitor BMS-790052

(2011) R. A. Fridell et al.   JOURNAL OF VIROLOGY

Resistance Analysis of the Hepatitis C Virus NS5A Inhibitor BMS-790052 in an In Vitro Replicon System

(2010) R. A. Fridell et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Modulation of interferon signaling by hepatitis C virus non-structural 5A protein: Implication of genotypic difference in interferon treatment

(2010) Sang-Min Kang et al.   FEBS LETTERS

Hepatitis C Virus Regulates Transforming Growth Factor β1 Production Through the Generation of Reactive Oxygen Species in a Nuclear Factor κB–Dependent Manner

(2010) Wenyu Lin et al.   GASTROENTEROLOGY

Recombinant HCV Variants With NS5A From Genotypes 1–7 Have Different Sensitivities to an NS5A Inhibitor but Not Interferon-α

(2010) Troels K.H. Scheel et al.   GASTROENTEROLOGY

c-Jun mediates hepatitis C virus hepatocarcinogenesis through signal transducer and activator of transcription 3 and nitric oxide-dependent impairment of oxidative DNA repair

(2010) Keigo Machida et al.   HEPATOLOGY

HIV and HCV Cooperatively Promote Hepatic Fibrogenesis via Induction of Reactive Oxygen Species and NFκB

(2010) Wenyu Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL28B inhibits hepatitis C virus replication through the JAK–STAT pathway

(2010) Leiliang Zhang et al.   JOURNAL OF HEPATOLOGY

Correlation between mutations in the core and NS5A genes of hepatitis C virus genotypes 1a, 1b, 3a, 3b, 6f and the response to pegylated interferon and ribavirin combination therapy

(2010) K. Kumthip et al.   JOURNAL OF VIRAL HEPATITIS

Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect

(2010) Min Gao et al.   NATURE

The non-structural 5A protein of hepatitis C virus exhibits genotypic differences in interferon antagonism

(2008) Ya-Hui Tsai et al.   JOURNAL OF HEPATOLOGY

Regulation of Hepatitis C Virion Production via Phosphorylation of the NS5A Protein

(2008) Timothy L. Tellinghuisen et al.   PLoS Pathogens