Gag Cytotoxic T Lymphocyte Escape Mutations Can Increase Sensitivity of HIV-1 to Human TRIM5 , Linking Intrinsic and Acquired Immunity

Role of TRIM5  RING Domain E3 Ubiquitin Ligase Activity in Capsid Disassembly, Reverse Transcription Blockade, and Restriction of Simian Immunodeficiency Virus

(2011) J. Kim et al.   JOURNAL OF VIROLOGY

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

(2011) Thomas Pertel et al.   NATURE

QUASI analysis of host immune responses to Gag polyproteins of human immunodeficiency virus type 1 by a systematic bioinformatics approachThis paper is one of a selection of papers published in this special issue entitled “Second International Symposium on Recent Advances in Basic, Clinical, and Social Medicine” and has undergone the Journal's usual peer review process.

(2010) Binhua Liang et al.   Biochemistry and Cell Biology

Long-term balancing selection maintains trans-specific polymorphisms in the human TRIM5 gene

(2010) R. Cagliani et al.   HUMAN GENETICS

Strain-Specific Differences in the Impact of Human TRIM5 , Different TRIM5  Alleles, and the Inhibition of Capsid-Cyclophilin A Interactions on the Infectivity of HIV-1

(2010) E. Battivelli et al.   JOURNAL OF VIROLOGY

Early Selection in Gag by Protective HLA Alleles Contributes to Reduced HIV-1 Replication Capacity That May Be Largely Compensated for in Chronic Infection

(2010) M. A. Brockman et al.   JOURNAL OF VIROLOGY

Control of HIV-1 in Elite Suppressors despite Ongoing Replication and Evolution in Plasma Virus

(2010) K. A. O'Connell et al.   JOURNAL OF VIROLOGY

Immunology and the elusive AIDS vaccine

(2010) Herbert W. Virgin et al.   NATURE

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation

(2010)   SCIENCE

Molecular evolution of the antiretroviral TRIM5 gene

(2009) Welkin E. Johnson et al.   IMMUNOGENETICS

Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703–positive individuals and their transmission recipients

(2009) Hayley Crawford et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human TRIM5α Expression Levels and Reduced Susceptibility to HIV‐1 Infection

(2009) Shamman Sewram et al.   JOURNAL OF INFECTIOUS DISEASES

Maternal Transmission of Human Immunodeficiency Virus Escape Mutations Subverts HLA-B57 Immunodominance but Facilitates Viral Control in the Haploidentical Infant

(2009) A. Schneidewind et al.   JOURNAL OF VIROLOGY

Impact of HLA in Mother and Child on Disease Progression of Pediatric Human Immunodeficiency Virus Type 1 Infection

(2009) C. F. Thobakgale et al.   JOURNAL OF VIROLOGY

HLA Footprints on Human Immunodeficiency Virus Type 1 Are Associated with Interclade Polymorphisms and Intraclade Phylogenetic Clustering

(2009) P. C. Matthews et al.   JOURNAL OF VIROLOGY

HLA-Associated Immune Escape Pathways in HIV-1 Subtype B Gag, Pol and Nef Proteins

(2009) Zabrina L. Brumme et al.   PLoS One

Modulation of HIV-1 infectivity and cyclophilin A-dependence by Gag sequence and target cell type

(2009) Saori Matsuoka et al.   Retrovirology

Variable Fitness Impact of HIV-1 Escape Mutations to Cytotoxic T Lymphocyte (CTL) Response

(2009) Ryan M. Troyer et al.   PLoS Pathogens

Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipients

(2008) Paul A. Goepfert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Structural and Functional Constraints Limit Options for Cytotoxic T-Lymphocyte Escape in the Immunodominant HLA-B27-Restricted Epitope in Human Immunodeficiency Virus Type 1 Capsid

(2008) A. Schneidewind et al.   JOURNAL OF VIROLOGY

Transmission and Long-Term Stability of Compensated CD8 Escape Mutations

(2008) A. Schneidewind et al.   JOURNAL OF VIROLOGY

Transmission of Human Immunodeficiency Virus Type 1 from a Patient Who Developed AIDS to an Elite Suppressor

(2008) J. R. Bailey et al.   JOURNAL OF VIROLOGY

HLA-B57/B*5801 Human Immunodeficiency Virus Type 1 Elite Controllers Select for Rare Gag Variants Associated with Reduced Viral Replication Capacity and Strong Cytotoxic T-Lymphotye Recognition

(2008) T. Miura et al.   JOURNAL OF VIROLOGY

Implication of TRIMalpha and TRIMCyp in interferon-induced anti-retroviral restriction activities

(2008) Laetitia Carthagena et al.   Retrovirology

Phylogenetic Dependency Networks: Inferring Patterns of CTL Escape and Codon Covariation in HIV-1 Gag

(2008) Jonathan M. Carlson et al.   PLoS Computational Biology

Transmission of HIV-1 CTL Escape Variants Provides HLA-Mismatched Recipients with a Survival Advantage

(2008) Denis R. Chopera et al.   PLoS Pathogens