Low-Dose Penile SIVmac251 Exposure of Rhesus Macaques Infected with Adenovirus Type 5 (Ad5) and Then Immunized with a Replication-Defective Ad5-Based SIV gag/pol/nef Vaccine Recapitulates the Results of the Phase IIb Step Trial of a Similar HIV-1 Vaccine

SIVmac251 Is Inefficiently Transmitted to Rhesus Macaques by Penile Inoculation with a Single SIVenv Variant Found in Ramp-up Phase Plasma

(2011) Zhong-Min Ma et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

An Ad5-Vectored HIV-1 Vaccine Elicits Cell-mediated Immunity but does not Affect Disease Progression in HIV-1–infected Male Subjects: Results From a Randomized Placebo-Controlled Trial (The Step Study)

(2011) D. W. Fitzgerald et al.   JOURNAL OF INFECTIOUS DISEASES

Host Genetic Determinants of T Cell Responses to the MRKAd5 HIV-1 gag/pol/nef Vaccine in the Step Trial

(2011) Jacques Fellay et al.   JOURNAL OF INFECTIOUS DISEASES

The TRIM5 Gene Modulates Penile Mucosal Acquisition of Simian Immunodeficiency Virus in Rhesus Monkeys

(2011) W. W. Yeh et al.   JOURNAL OF VIROLOGY

Genetic impact of vaccination on breakthrough HIV-1 sequences from the STEP trial

(2011) Morgane Rolland et al.   NATURE MEDICINE

Pre-Existing Adenovirus Immunity Modifies a Complex Mixed Th1 and Th2 Cytokine Response to an Ad5/HIV-1 Vaccine Candidate in Humans

(2011) Samuel O. Pine et al.   PLoS One

Serological immunity to adenovirus serotype 5 is not associated with risk of HIV infection: a case–control study

(2010) Marcel E Curlin et al.   AIDS

A Limited Number of Simian Immunodeficiency Virus (SIV) env Variants Are Transmitted to Rhesus Macaques Vaginally Inoculated with SIVmac251

(2010) M. Stone et al.   JOURNAL OF VIROLOGY

Low-Dose Mucosal Simian Immunodeficiency Virus Infection Restricts Early Replication Kinetics and Transmitted Virus Variants in Rhesus Monkeys

(2010) J. Liu et al.   JOURNAL OF VIROLOGY

TRIM5 Suppresses Cross-Species Transmission of a Primate Immunodeficiency Virus and Selects for Emergence of Resistant Variants in the New Species

(2010) Andrea Kirmaier et al.   PLOS BIOLOGY

TRIM5α Modulates Immunodeficiency Virus Control in Rhesus Monkeys

(2010) So-Yon Lim et al.   PLoS Pathogens

Assessing Vaccine Effects in Repeated Low-Dose Challenge Experiments

(2009) Michael G. Hudgens et al.   BIOMETRICS

Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1

(2009) Brandon F. Keele et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Power to Detect the Effects of HIV Vaccination in Repeated Low‐Dose Challenge Experiments

(2009) Michael G. Hudgens et al.   JOURNAL OF INFECTIOUS DISEASES

Efficacy of Multivalent Adenovirus-Based Vaccine against Simian Immunodeficiency Virus Challenge

(2009) D. R. Casimiro et al.   JOURNAL OF VIROLOGY

Vaccine-Induced Cellular Responses Control Simian Immunodeficiency Virus Replication after Heterologous Challenge

(2009) N. A. Wilson et al.   JOURNAL OF VIROLOGY

Limited dissemination of pathogenic SIV after vaginal challenge of rhesus monkeys immunized with a live, attenuated lentivirus

(2009) Mars Stone et al.   VIROLOGY

Safety and Immunogenicity of a Replication‐Incompetent Adenovirus Type 5 HIV‐1 Clade Bgag/pol/nefVaccine in Healthy Adults

(2008) Frances H. Priddy et al.   CLINICAL INFECTIOUS DISEASES

Real-Time PCR with an Internal Control for Detection of All Known Human Adenovirus Serotypes

(2008) M. Damen et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Antiviral CD8+T cells in the genital tract control viral replication and delay progression to AIDS after vaginal SIV challenge in rhesus macaques immunized with virulence attenuated SHIV 89.6

(2008) M. Genescà et al.   JOURNAL OF INTERNAL MEDICINE

With Minimal Systemic T-Cell Expansion, CD8+ T Cells Mediate Protection of Rhesus Macaques Immunized with Attenuated Simian-Human Immunodeficiency Virus SHIV89.6 from Vaginal Challenge with Simian Immunodeficiency Virus

(2008) M. Genesca et al.   JOURNAL OF VIROLOGY

HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case–cohort analysis

(2008) M Juliana McElrath et al.   LANCET

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET

The Use of Nonhuman Primate Models in HIV Vaccine Development

(2008) Cecilia Morgan et al.   PLOS MEDICINE