LEDGF Dominant Interference Proteins Demonstrate Prenuclear Exposure of HIV-1 Integrase and Synergize with LEDGF Depletion To Destroy Viral Infectivity

LEDGF Hybrids Efficiently Retarget Lentiviral Integration Into Heterochromatin

(2010) Rik Gijsbers et al.   MOLECULAR THERAPY

Retroviral intasome assembly and inhibition of DNA strand transfer

(2010) Stephen Hare et al.   NATURE

APOBEC3 proteins mediate the clearance of foreign DNA from human cells

(2010) Mark D Stenglein et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Lens epithelium-derived growth factor fusion proteins redirect HIV-1 DNA integration

(2010) A. L. Ferris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromatin tethering and retroviral integration: Recent discoveries and parallels with DNA viruses

(2009) Anne M. Meehan et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Lens Epithelium-derived Growth Factor/p75 Interacts with the Transposase-derived DDE Domain of PogZ

(2009) Koen Bartholomeeusen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrase Interacts with Nucleoporin NUP153 To Mediate the Nuclear Import of Human Immunodeficiency Virus Type 1

(2009) C. L. Woodward et al.   JOURNAL OF VIROLOGY

The Interaction Between Lentiviral Integrase and LEDGF: Structural and Functional Insights

(2009) Stephen Hare et al.   Viruses-Basel

LEDGF/p75 Proteins with Alternative Chromatin Tethers Are Functional HIV-1 Cofactors

(2009) Anne M. Meehan et al.   PLoS Pathogens

A Novel Co-Crystal Structure Affords the Design of Gain-of-Function Lentiviral Integrase Mutants in the Presence of Modified PSIP1/LEDGF/p75

(2009) Stephen Hare et al.   PLoS Pathogens

Structural Basis for Functional Tetramerization of Lentiviral Integrase

(2009) Stephen Hare et al.   PLoS Pathogens

Menin Critically Links MLL Proteins with LEDGF on Cancer-Associated Target Genes

(2008) Akihiko Yokoyama et al.   CANCER CELL

Integrase, LEDGF/p75 and HIV replication

(2008) E. M. Poeschla   CELLULAR AND MOLECULAR LIFE SCIENCES

Dynamic Modulation of HIV-1 Integrase Structure and Function by Cellular Lens Epithelium-derived Growth Factor (LEDGF) Protein

(2008) Christopher J. McKee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Lentiviral Integrase Binding Protein LEDGF/p75 and HIV-1 Replication

(2008) Alan Engelman et al.   PLoS Pathogens