Journal
APPLIED RADIATION AND ISOTOPES
Volume 106, Issue -, Pages 151-155Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.apradiso.2015.07.028
Keywords
BNCT; Magnetic Drug Targeting; Nanomedicine
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The selective delivery of 1013 into the tumor tissue remains to be further improved for successful and reliable Boron Neutron Capture Therapy applications. Magnetic Drug Targeting using intraarterially administered superparamagnetic nanoparticles and external magnetic fields already exhibited convincing results in terms of highly efficient and selective drug deposition. Using the same technique for the targeted 1 B delivery is a promising new approach. Here, systematic irradiation experiments of phantom cubes containing different concentrations of boron and nanoparticles as well as varying three-dimensional arrangements have been performed. (C) 2015 Published by Elsevier Ltd.
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