Journal
JOURNAL OF VIROLOGY
Volume 82, Issue 24, Pages 12589-12590Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.01394-08
Keywords
-
Categories
Funding
- NIH [R01 AI065960]
- Reeder Centennial Fellowship
Ask authors/readers for more resources
We explored the relationship between fitness change and population size during transmission in vesicular stomatitis populations of very high fitness. The results show a linear correlation between the logarithm of the critical bottleneck size (population size at which there are no significant fitness changes after 20 passages) and the initial fitness of the population. In addition, limits to fitness increases during large-population passages of very-high-fitness strains were abolished by increasing the population size during transmission, indicating that beneficial variation is still available in these populations.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available