Article
Cardiac & Cardiovascular Systems
Oded Breuer, Laurice Boursheh, Ephraim Bar-Yishay, Avigdor Hevroni
Summary: This study evaluated infant pulmonary function tests in individuals with Down syndrome. The results showed that most infants with Down syndrome had obstructive lung disease with mildly increased lung volumes and significantly decreased expiratory flows. These findings are important for better understanding of early lung disease in infants with Down syndrome.
RESPIRATORY MEDICINE
(2022)
Article
Respiratory System
Toby M. Maher, Susanne Stowasser, Florian Voss, Elisabeth Bendstrup, Michael Kreuter, Fernando J. Martinez, Patricia J. Sime, Christian Stock
Summary: This study used clinical trial data of nintedanib in patients with pulmonary fibrosis to assess decline in forced vital capacity (FVC) as a surrogate for mortality. The results showed a strong association between the rate of decline in FVC % predicted and the risk of death over 52 weeks, supporting FVC decline as a surrogate for mortality in these patients.
Article
Radiology, Nuclear Medicine & Medical Imaging
Layla Diab-Caceres, Rosa Maria Giron-Moreno, Elena Garcia-Castillo, Maria Teresa Pastor-Sanz, Casilda Olveira, Marta Maria Garcia-Clemente, Rosa Nieto-Royo, Concha Prados-Sanchez, Paloma Caballero-Sanchez, Maria Jose Olivera-Serrano, Alicia Padilla-Galo, Encarnacion Nava-Tomas, Amparo Esteban-Peris, Maria Fernandez-Velilla, Maribel Torres, Rosa Mar Gomez-Punter, Julio Ancochea
Summary: The study found that the modified Bhalla score can predict future PEx in CF patients and is well correlated with pulmonary function test results. A statistical model based on the overall Bhalla score was constructed to predict the number of PEx.
EUROPEAN RADIOLOGY
(2021)
Article
Medicine, General & Internal
Katarzyna Walicka-Serzysko, Magdalena Postek, Urszula Borawska-Kowalczyk, Justyna Milczewska, Dorota Sands
Summary: This prospective study aimed to assess the course of early lung disease in children with cystic fibrosis (CF) using multiple breath nitrogen washout (MBNW), impulse oscillometry (IOS), and conventional techniques. The results showed that MBNW and IOS are more helpful tools than conventional techniques in evaluating early lung disease in CF. The lung clearance index (LCI) is a more useful parameter than forced expiratory volume in 1 second (FEV1) for detecting functional abnormalities in school-age children.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, Research & Experimental
Ahmet Arisoy, Abdullah Yilgor, Ibrahim H. Uney
Summary: Patients with COPD are at a higher risk of developing peripheral neuropathy, especially motor neuropathy. The Global Initiative for Chronic Obstructive Lung Disease classifies these neuropathies as group D. Various factors may contribute to the accelerated development of neuropathy.
MEDICAL SCIENCE MONITOR
(2021)
Article
Agriculture, Dairy & Animal Science
Jorge Isidoro Matos, Alicia Caro-Vadillo, Yaiza Falcon-Cordon, Sara Nieves Garcia-Rodriguez, Noelia Costa-Rodriguez, Elena Carreton, Jose Alberto Montoya-Alonso
Summary: This study evaluated the effectiveness of the pulmonary vein to pulmonary artery ratio (PV:PA ratio) in detecting pulmonary hypertension (PH) caused by heartworms in dogs. The results showed that the PV:PA ratio can be used as a complementary diagnostic method to estimate the presence of moderate or severe PH in these patients.
Article
Biotechnology & Applied Microbiology
Gustavo de Sa Schiavo Matias, Ana Claudia O. Carreira, Vitoria Frias Batista, Hianka Jasmyne Costa de Carvalho, Maria Angelica Miglino, Paula Fratini
Summary: Decellularized extracellular matrix can be used as a biomaterial for tissue engineering, particularly for partial trachea replacement. In this study, acellular canine tracheal scaffolds with preserved ECM structure and proteins were obtained and evaluated for cell adhesion and proliferation. The results showed successful recellularization of the scaffolds with canine tracheal epithelial cells and yolk sac endothelial progenitor cells. In vivo implantation in mice confirmed the preserved tissue and absence of fibrotic tissue process. This study demonstrates the potential of recellularized scaffolds for future applications in tissue engineering.
Article
Multidisciplinary Sciences
P. Jacquerie, B. Andre, D. De Seny, M. Henket, L. Giltay, M. Ernst, R. Louis, M. Malaise, C. Ribbens, J. Guiot
Summary: This study aimed to assess the test-retest reliability and reproducibility of pulmonary function testing (PFT) in SSc patients with or without interstitial lung disease (ILD). The results showed that the PFT parameters were reproducible over time and in both groups, suggesting their use in clinical practice.
SCIENTIFIC REPORTS
(2023)
Article
Medicine, General & Internal
Xin Dong, Yanli Gao, Man Li, Dong Wang, Jifeng Li, Yongfeng Zhang
Summary: The characteristics of elderly-onset primary Sjogren syndrome (pSS) were investigated using chest high-resolution computed tomography and pulmonary function tests (PFTs). The data of 102 patients with pSS with interstitial lung disease were retrospectively analyzed. Among them, 34 were in the elderly-onset pSS (EopSS) group (>= 65 years) and 68 were in the adult-onset pSS (AopSS) group (<65 years). EopSS patients showed a higher incidence of usual interstitial pneumonia and a lower incidence of nonspecific interstitial pneumonia compared to AopSS patients. The EopSS group had its own characteristics in terms of lung involvement and pulmonary function.
Article
Cardiac & Cardiovascular Systems
Jesus Diez-Manglano, Uxua Asin Samper
Summary: This study conducted a meta-analysis of 39 studies and found that type-1 diabetes is associated with impaired pulmonary function, independent of age, sex, smoking, BMI, and geographical region. Longitudinal studies are needed to further investigate the association between T1D patients and impaired pulmonary function.
RESPIRATORY MEDICINE
(2022)
Review
Surgery
Gunel Guliyeva, Joseph Y. Cheung, Francisco R. Avila, Maria T. Huayllani, Daniel Boczar, Peter N. Broer, Antonio Jorge Forte
Summary: Breast hypertrophy can impact respiratory function, reduction mammoplasty improves lung function parameters and alleviates symptoms in patients with respiratory complaints, though further studies are needed to address the heterogeneity among studies.
ANNALS OF PLASTIC SURGERY
(2021)
Article
Medicine, General & Internal
Katarzyna Guziejko, Anna Moniuszko-Malinowska, Piotr Czupryna, Marlena Dubatowka, Magda Lapinska, Andrzej Raczkowski, Pawel Sowa, Lukasz Kiszkiel, Lukasz Minarowski, Marcin Moniuszko, Monika Groth, Karol A. Kaminski
Summary: This study investigated the impact of COVID-19 on pulmonary function tests in patients six months after recovery, and examined whether routine testing should be conducted in post-COVID-19 patients. The results showed that some patients still experienced symptoms such as cough and shortness of breath six months after recovery, and their pulmonary function parameters were decreased compared to those without these symptoms.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Pediatrics
Gokcen Kartal Ozturk, Burcin Beken, Sumeyra Dogan, Himmet Haluk Akar
Summary: The study found that some children may experience persistent respiratory symptoms after COVID-19 infection, regardless of disease severity, potentially due to inflammation affecting the peripheral airways.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Review
Medicine, General & Internal
Andre Dankert, Thorsten Dohrmann, Benjamin Loeser, Antonia Zapf, Christian Zoellner, Martin Petzoldt
Summary: This systematic review summarizes the available scientific literature regarding the ability of pulmonary function tests (PFTs) to predict postoperative pulmonary complications (PPC) in non-thoracic surgery. The results indicate that it is currently unknown if PFTs improve risk assessment before non-thoracic surgery.
DEUTSCHES ARZTEBLATT INTERNATIONAL
(2022)
Article
Veterinary Sciences
Elodie Roels, Aline Fastres, Anne-Christine Merveille, Geraldine Bolen, Erik Teske, Cecile Clercx, Kathleen Mc Entee
Summary: This study revealed a high prevalence of PH at diagnosis in West Highland white terriers affected with canine idiopathic pulmonary fibrosis, with PV/PA serving as a useful non-invasive surrogate for assessing PH. The presence of moderate/severe PH at initial presentation was not associated with survival outcome.
BMC VETERINARY RESEARCH
(2021)