Review
Biochemistry & Molecular Biology
Yi Zhao, De-Chao Tan, Bo Peng, Lin Yang, Si-Yuan Zhang, Rui-Peng Shi, Cheong-Meng Chong, Zhang-Feng Zhong, Sheng-Peng Wang, Qiong-Lin Liang, Yi-Tao Wang
Summary: Eucommia ulmoides, a popular medicinal herb in East Asia, has potential applications in NEI-related diseases, but clinical studies are limited. Its derivatives in China are diverse, mainly used for immunity enhancement, liver protection, bone strengthening, and blood pressure reduction.
Article
Plant Sciences
Peng Deng, Yiran Wang, Fengcheng Hu, Hang Yu, Yangling Liang, Haolin Zhang, Ting Wang, Yuhao Zhou, Zhouqi Li
Summary: This study analyzed the effects of different variation sources on the phenotypic traits of Eucommia ulmoides, finding that site effect accounted for the largest proportion of variance, followed by genotype and genotype x environment interaction effects. The study showed that preferred genotypes and cultivation areas can be selected to improve the traits, and that growth traits and economic traits can be improved simultaneously. Moreover, the study identified annual mean temperature and annual sunshine duration as crucial factors affecting the traits.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Multidisciplinary Sciences
Ting Wang, Liming Fan, Shuai Feng, Xinli Ding, Xinxin An, Jiahuan Chen, Minjuan Wang, Xifeng Zhai, Yang Li
Summary: This study clarified the chemical components and molecular mechanism of iridoid glycosides from Eucommia ulmoides Oliver in treating osteoporosis through network pharmacology and molecular simulations, suggesting a multi-component, multi-target, and multi-pathway mechanism.
SCIENTIFIC REPORTS
(2022)
Article
Pharmacology & Pharmacy
Yaqiong Sun, Kui Huang, Linhai Mo, Akhlaq Ahmad, Dejia Wang, Zijie Rong, Honghui Peng, Honghua Cai, Guihua Liu
Summary: Eucommia ulmoides polysaccharides (EUP) have a beneficial effect on the proliferation of macrophages. In an osteoarthritis model, EUP can inhibit the expression of inflammation-related genes and promote the expression of osteogenic and cartilage-related genes, thus reducing the degree of articular cartilage destruction. EUP may delay the progression of osteoarthritis by regulating the polarization state of macrophages.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Chemistry, Physical
Shiye Zhu, Jianhua Zeng, Chen Pan, Youzheng Chai, Ma Bai, Jiaxing Li, Anwei Chen
Summary: A tea polyphenols-loaded water-in-oil microemulsion was developed to effectively retard lipid oxidation in polyunsaturated fatty acids-rich oil. The low-dose tea polyphenols showed a better inhibitory effect on lipid oxidation compared to high-dose tea polyphenols. These findings demonstrate that the tea polyphenols microemulsion can effectively inhibit the oxidation of polyunsaturated fatty acids-rich oil.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Food Science & Technology
Rui Xue, Wen Zhang, Zhou-Ping Wang, Ming-Qiang Zhu
Summary: Wood vinegar was extracted from Eucommia ulmoides Oliver branches and refined using various methods. The refined wood vinegar was then used to treat cherry tomatoes and strawberries to evaluate their storage performance. The results showed that using ultra-low freezing and thawing method resulted in pH reduction, firmness loss, delayed weight loss and decay incidence of the berries. Additionally, the refined wood vinegar reduced the loss of vitamin C content and total soluble solids of the berries. These findings provide a basis for further development of refined wood vinegar as a food preservative.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Agricultural Engineering
Xin Ran, Yu Liu, Degang Zhao
Summary: The study found that the EuSRPP1 gene in Eucommia ulmoides Oliver significantly influences the chain elongation, particle development, and content of rubber.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Plant Sciences
Dan Ouyang, Lan-Chun Wang, Ting Tang, Hong Feng
Summary: Eucommia ulmoides Oliver is a valuable woody plant known for its traditional medicinal use in East Asia, with its dried bark containing various glycosides recognized for their pharmacological properties. Uridine diphosphate glycosyltransferases (UGTs) play a key role in the biosynthesis of glycosides, with 91 putative EuUGT genes identified and categorized into 14 groups through genomic analysis. Transcriptomic data revealed diverse expression patterns of EuUGTs across different organs and growing seasons. These findings will aid in further research on glycoside biosynthetic pathways in Eucommia ulmoides.
Article
Agricultural Engineering
Zhijie Shen, Xuran Ji, Shimiao Yao, Hairong Zhang, Lian Xiong, Hailong Li, Xuefang Chen, Xinde Chen
Summary: Chlorogenic acid, an important compound in Eucommia ulmoides Oliver leaves, was extracted using a second-order kinetic model. The study found that reducing particle size, increasing liquid-solid ratio, and temperature can enhance the extraction rate and yield. The researchers developed an empirical model to predict the extraction process and verified its feasibility.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Nutrition & Dietetics
Feng Kong, Qinghua Zeng, Yue Li, Yishuai Ding, Di Xue, Xingfeng Guo
Summary: This study used network pharmacology to reveal the potential compounds of Eucommia ulmoides Oliver bark that have antioxidant and antitumor properties. Quercetin was found to be the key compound in resisting oxidative damage and free radical damage. Steam explosion was used to enhance the release and activities of bioactive compounds in Eucommia ulmoides Oliver bark, resulting in increased antioxidative and antiproliferative properties.
FRONTIERS IN NUTRITION
(2022)
Article
Plant Sciences
Peng Deng, Xiangchen Xie, Feiyu Long, Liang Zhang, Yonghang Li, Zhangxu Zhao, Shiyao Yang, Yiran Wang, Ruishen Fan, Zhouqi Li
Summary: This study classified leaf-related traits of Eucommia ulmoides Oliver using a probability grading method, finding significant differences between different planting models and suggesting standards should be divided accordingly. By analyzing variation range, optimal planting models for different traits were determined. An evaluation system for leaf-related traits of EUO germplasm, considering planting models and stability, was established for the first time, serving as a reference for identifying and evaluating EUO germplasm resources and providing an example for the classification of quantitative traits in other economically important perennial plants.
Article
Agricultural Engineering
Rui Xue, Er-Liang Cui, Guo-Quan Hu, Ming-Qiang Zhu
Summary: The quality of wood vinegar was enhanced by refining it through various physicochemical methods. The refined wood vinegar obtained through ultra-low freezing and thawing method showed better quality with excellent antimicrobial and antioxidant activity.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Food Science & Technology
Jiang-Jiang Tang, Na Zhao, Yu-Qi Gao, Rui Han, Xiao-Ying Wang, Jun-Mian Tian, Jin-Ming Gao
Summary: Eucommia ulmoides seeds are rich in oil, with beta-sitosterol and iridoid glycosides identified as the main phytochemical substances. These compounds show inhibitory effects on NO production, suggesting a potential role in reducing the risk of neurodegenerative diseases.
Article
Genetics & Heredity
Ting Xu, Degang Zhao
Summary: Prohibitins (PHBs), as multifunctional proteins, play essential roles in many cellular processes. In this study, a PHB gene, EuPHB1, was cloned from Eucommia ulmoides and found to be located in mitochondria. Overexpression of EuPHB1 in tobacco resulted in chlorotic and shriveled leaves, and inhibited genes related to hormone and auxin signal transduction, auxin binding, and transport. Furthermore, EuPHB1 overexpression increased mitochondrial oxidative phosphorylation and cellular energy metabolism, leading to certain cellular phenotypic changes.
Article
Pharmacology & Pharmacy
Haibo Feng, Jie Yang, Hui Zhi, Xin Hu, Yan Yang, Linzi Zhang, Qianqian Liu, Yangyang Feng, Daiyan Wu, Hangyu Li
Summary: By coupling PsEUL and OVA to form PsEUL-OVA, the phagocytic activity of macrophages and dendritic cells is promoted, inducing both humoral and cellular immune responses. This novel delivery system significantly increases antibody and cytokine levels, activates T lymphocytes, and promotes DC maturation.
