Article
Veterinary Sciences
Abigail McGlennon, Andrew Waller, Kristien Verheyen, Josh Slater, John Grewar, David Aanensen, Richard Newton
Summary: This study provides insights into the diagnosis and clinical features of strangles in UK horses from 2015 to 2019, with a focus on symptoms such as nasal discharge and fever. However, limited or missing clinical history and signalment on laboratory submission forms restrict the completeness of the data.
Article
Microbiology
Bryce A. Thomas, Ryan K. Saylor, Zachary P. Taylor, DeLacy V. L. Rhodes
Summary: This study analyzed strangles case numbers in the United States from 2018 to 2022 to investigate temporal and weather patterns associated with outbreaks. The results suggest that changes in monthly average temperature and minimum temperature are significantly associated with the odds of strangles outbreaks.
Article
Veterinary Sciences
Ashley G. Boyle, Shelley C. Rankin, Kathleen O'Shea, Darko Stefanovski, Jing Peng, Jinzhao Song, Haim H. Bau
Summary: The eqbE LAMP microfluidic device showed potential for detecting S. equi in GPL specimens from convalescent horses, with comparable performance to a triplex qPCR assay, indicating it could be developed as a rapid, sensitive, accurate, and cost-efficient POC device for S. equi detection.
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2021)
Article
Immunology
Dharvi Chhabra, Tanvi Bhatia, Umesh Goutam, Anju Manuja, Balvinder Kumar
Summary: This article provides a comprehensive overview of strangles, including its global prevalence, clinical symptoms, transmission routes, diagnostic methods, treatment options, and preventive measures.
MICROBIAL PATHOGENESIS
(2023)
Article
Veterinary Sciences
Dordia Anindita Rotinsulu, Christa Ewers, Katharina Kerner, Amrozi Amrozi, Retno Damayanti Soejoedono, Torsten Semmler, Rolf Bauerfeind
Summary: This study aimed to characterize S. equi equi isolates obtained from suspected strangles cases in Indonesia in 2018. The results showed that all isolates belonged to ST179 and carried seM allele 166. The isolates differed from each other by only 2 to 14 cgSNPs and formed an exclusive sub-cluster within the BAPS-2 of S. equi equi cgMLST scheme. Furthermore, all isolates were susceptible to beta-lactam antibiotics penicillin G, ampicillin, and ceftiofur.
VETERINARY SCIENCES
(2023)
Article
Veterinary Sciences
Camilo Jaramillo-Morales, Kaitlyn James, Samantha Barnum, Wendy Vaala, Duane E. Chappell, Chrissie Schneider, Bryant Craig, Fairfield Bain, D. Craig Barnett, Earl Gaughan, Nicola Pusterla
Summary: This study aimed to describe selected prevalence factors of horses with acute onset of fever and respiratory signs testing positive for S. equi, as well as the impact of vaccination on S. equi detection.
VETERINARY SCIENCES
(2023)
Article
Genetics & Heredity
Catriona Mitchell, Karen F. Steward, Amelia R. L. Charbonneau, Saoirse Walsh, Hayley Wilson, John F. Timoney, Ulli Wernery, Marina Joseph, David Craig, Kees van Maanen, Annelies Hoogkamer- van Gennep, Albertine Leon, Lucjan Witkowski, Magdalena Rzewuska, Ilona Stefanska, Monika Zychska, Gunther van Loon, Ray Cursons, Olivia Patty, Els Acke, James R. Gilkerson, Charles El-Hage, Joanne Allen, Hiroshi Bannai, Yuta Kinoshita, Hidekazu Niwa, Teotimo Becu, John Pringle, Bengt Guss, Reinhard Bose, Yvonne Abbott, Lisa Katz, Bernadette Leggett, Tom C. Buckley, Shlomo E. Blum, Fatima Cruz Lopez, Ana Fernandez Ros, Maria Cristina Marotti Campi, Silvia Preziuso, Carl Robinson, J. Richard Newton, Ellen Schofield, Ben Brooke, Mike Boursnell, Nicolas de Brauwere, Roxane Kirton, Charlotte K. Barton, Khalil Abudahab, Ben Taylor, Corin A. Yeats, Richard Goater, David M. Aanensen, Simon R. Harris, Julian Parkhill, Matthew T. G. Holden, Andrew S. Waller
Summary: This study analyzed and visualized phylogenomic and epidemiological data of 670 isolates of Streptococcus equi from 19 countries, revealing the genetic relationships and transmission events of the equine disease strangles in horse populations worldwide. The data highlight the international importance of strangles and emphasize the need for recognition and prevention strategies.
MICROBIAL GENOMICS
(2021)
Article
Multidisciplinary Sciences
Ellen Ruth A. Morris, Ashley G. Boyle, Miia Riihimaeki, Anna Aspan, Eman Anis, Andrew E. Hillhouse, Ivan Ivanov, Angela I. Bordin, John Pringle, Noah D. Cohen
Summary: Research using next-generation sequencing technologies found no significant or consistent differences in the genome, methylome, and transcriptome of isolates of the bacterium Streptococcus equi subsp. equi (SEE) from horses with acute clinical strangles and inapparent carrier horses. This suggests that adaptations of SEE to the host are unlikely to explain the carrier state of the pathogen. Instead, efforts to understand the carrier state of SEE should focus on host factors.
Review
Veterinary Sciences
Luke A. A. McLinden, Sarah L. L. Freeman, Janet Daly, Adam Blanchard, Jeremy G. G. Kemp-Symonds, Andrew Waller
Summary: This review discusses the pathogenic mechanism, clinical manifestations, and future prevention and treatment measures of S. equi, the causative organism of strangles in equids. S. equi evolved from a commensal and occasionally opportunistic pathogen, and its success lies in its ability to cause both acute and persistent infections. Insights into the S. equi genome and lifestyle have led to advancements in diagnostic assays and the development of a safe and effective recombinant-fusion vaccine.
EQUINE VETERINARY EDUCATION
(2023)
Article
Veterinary Sciences
Carla P. Bustos, Alejandra J. Munoz, Nora Guida, Andrew Waller, Maria Mesplet
Summary: This study identified and compared the seM types of Argentine isolates of Streptococcus equi subsp. equi using molecular and phylogenetic approaches, resulting in the discovery of seven novel seM types. The high genetic similarity observed among Argentine and Brazilian seM types suggests a geographical distribution of strain types, likely reflecting the movement of horses between different equine disciplines and neighboring countries.
EQUINE VETERINARY JOURNAL
(2022)
Article
Microbiology
Ellen Ruth A. Morris, Jing Wu, Angela Bordin, Sara D. Lawhon, Noah D. Cohen
Summary: This study characterized the genomic and methylomic differences of multiple SEE and SEZ isolates from Texas. The results showed that genetic mobile elements in SEE and differential methylation of shared genes between SEE and SEZ might contribute to the host specificity of SEE.
MICROBIOLOGY SPECTRUM
(2022)
Article
Veterinary Sciences
Rosa M. A. C. Houben, Kees van Maanen, Jeremy G. Kemp-Symonds, Andrew S. Waller, Marianne M. Sloet van Oldruitenborgh-Oosterbaan, Hans Heesterbeek
Summary: This study estimated the basic reproduction number (R-0) for Streptococcus equi (S. equi) in equine populations through a systematic review and meta-analysis of outbreak data. The estimated R-0 for S. equi was 2.2-2.7, providing valuable information for future prevention strategies.
EQUINE VETERINARY JOURNAL
(2023)
Article
Veterinary Sciences
Ashley G. Boyle, Kathleen O'Shea, Darko Stefanovski, Shelley C. Rankin
Summary: PMA qPCR can differentiate viable and nonviable S. equi bacteria, with good performance in both positive and suspect positive clinical specimens. Testing on fresh specimens yields more accurate results.
JOURNAL OF EQUINE VETERINARY SCIENCE
(2023)
Review
Veterinary Sciences
Maria C. Duran, Lutz S. Goehring
Summary: Strangles, caused by Streptococcus equi spp. equi, is a common disease in horses worldwide, leading to negative impact on equine health and significant economic losses to the equine industry. Control and prevention of the disease are crucial for maintaining premises and equine health.
AUSTRAL JOURNAL OF VETERINARY SCIENCES
(2021)
Review
Microbiology
Anna Wasniewska-Wlodarczyk, Renata Pepas, Renata Janowicz, Wieslaw Konopka
Summary: This report presents an extremely rare case of retropharyngeal abscess in a 12-year-old girl caused by an infection of Streptococcus equi subsp. equi.
Article
Biochemical Research Methods
Yanhong Tong, Wen Tang, Hyun-Jin Kim, Xiaojing Pan, Tamara A. Ranalli, Huimin Kong
Article
Biotechnology & Applied Microbiology
Yanhong Tong, Bertrand Lemieux, Huimin Kong
Article
Pathology
Wing Huen A. Chow, Cindy McCloskey, Yanhong Tong, Lin Hu, Qimin You, Ciaran P. Kelly, Huimin Kong, Yi-Wei Tang, Wen Tang
JOURNAL OF MOLECULAR DIAGNOSTICS
(2008)
Article
Pathology
Yanhong Tong, Kaitlin McCarthy, Huimin Kong, Bertrand Lemieux
JOURNAL OF MOLECULAR DIAGNOSTICS
(2012)
Article
Biology
YH Tong, HN Guo, JM Brewer, H Lee, MN Lehman, EL Bittman
JOURNAL OF BIOLOGICAL RHYTHMS
(2004)
Review
Biochemistry & Molecular Biology
YH Tong, D Arking, S Ye, B Reinhold, V Reinhold, DC Stein
Article
Microbiology
YH Tong, V Reinhold, B Reinhold, B Brandt, DC Stein
JOURNAL OF BACTERIOLOGY
(2001)