Insights into the Activity, Differential Expression, Mutual Regulation, and Functions of Matrix Metalloproteinases and A Disintegrin and Metalloproteinases in Hypertension and Cardiac Disease

Pressure overload-dependent membrane type 1-matrix metalloproteinase induction: relationship to LV remodeling and fibrosis

(2012) Michael R. Zile et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The renin-angiotensin system: a target of and contributor to dyslipidemias, altered glucose homeostasis, and hypertension of the metabolic syndrome

(2012) Kelly Putnam et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

G-protein-coupled receptors as fat sensors

(2012) Marco A.R. Vinolo et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Report of the National Heart, Lung, and Blood Institute Working Group on Epigenetics and Hypertension

(2012) Allen W. Cowley et al.   HYPERTENSION

Pharmacological Stabilization of Intracranial Aneurysms in Mice

(2012) Hiroshi Makino et al.   STROKE

Doxycycline, a matrix metalloprotease inhibitor, reduces vascular remodeling and damage after cerebral ischemia in stroke-prone spontaneously hypertensive rats

(2011) Paulo W. Pires et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Inward remodeling of resistance arteries requires reactive oxygen species-dependent activation of matrix metalloproteinases

(2011) Luis A. Martinez-Lemus et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The history of the tetracyclines

(2011) Mark L. Nelson et al.   Annals of the New York Academy of Sciences

Analysis of apolipoprotein A-I as a substrate for matrix metalloproteinase-14

(2011) Jun Hyoung Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of matrix metalloproteinase-2 improves endothelial function and prevents hypertension in insulin-resistant rats

(2011) PR Nagareddy et al.   BRITISH JOURNAL OF PHARMACOLOGY

Diversity of Myocardial Interstitial Proteolytic Pathways

(2011) Francis G. Spinale   CIRCULATION

Targeted Imaging of the Spatial and Temporal Variation of Matrix Metalloproteinase Activity in a Porcine Model of Postinfarct Remodeling

(2011) Zakir H. Sahul et al.   Circulation-Cardiovascular Imaging

Plasma Biomarkers That Reflect Determinants of Matrix Composition Identify the Presence of Left Ventricular Hypertrophy and Diastolic Heart Failure

(2011) Michael R. Zile et al.   Circulation-Heart Failure

Long-Term MMP Inhibition by Doxycycline Exerts Divergent Effect on Ventricular Extracellular Matrix Deposition and Systolic Performance in Stroke-Prone Spontaneously Hypertensive Rats

(2011) Shan Zeng et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

An Emerging Role of Degrading Proteinases in Hypertension and the Metabolic Syndrome: Autodigestion and Receptor Cleavage

(2011) Geert W. Schmid-Schönbein   CURRENT HYPERTENSION REPORTS

The role of ADAM-mediated shedding in vascular biology

(2011) Daniela Dreymueller et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Can emerging biomarkers of myocardial remodelling identify asymptomatic hypertensive patients at risk for diastolic dysfunction and diastolic heart failure?

(2011) Patrick Collier et al.   EUROPEAN JOURNAL OF HEART FAILURE

5,7-Dimethoxyflavone, an activator of PPARα/γ, inhibits UVB-induced MMP expression in human skin fibroblast cells

(2011) Jae Kyung Kim et al.   EXPERIMENTAL DERMATOLOGY

Statins and myocardial remodelling: cell and molecular pathways

(2011) Karen E. Porter et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Cell cholesterol modulates metalloproteinase-dependent shedding of low-density lipoprotein receptor-related protein-1 (LRP-1) and clearance function

(2011) Charlotte Selvais et al.   FASEB JOURNAL

Nuclear Factor Kappa B and Matrix Metalloproteinase Induced Receptor Cleavage in the Spontaneously Hypertensive Rat

(2011) Kwan-I Sharon Wu et al.   HYPERTENSION

Apolipoprotein A-IV is a novel substrate for matrix metalloproteinases

(2011) Ji Yoon Park et al.   JOURNAL OF BIOCHEMISTRY

Plasma levels of matrix metalloproteinases and their inhibitors in hypertension

(2011) Chiara Marchesi et al.   JOURNAL OF HYPERTENSION

Regulation of Blood Pressure and Salt Homeostasis by Endothelin

(2011) Donald E. Kohan et al.   PHYSIOLOGICAL REVIEWS

Tissue inhibitors of metalloproteinases

(2011) Gillian Murphy   GENOME BIOLOGY

Associations Between Collagen Synthesis and Degradation and Aortic Function in Arterial Hypertension

(2010) D. A. Stakos et al.   AMERICAN JOURNAL OF HYPERTENSION

Receptor cleavage reduces the fluid shear response in neutrophils of the spontaneously hypertensive rat

(2010) Angela Y. Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Matrix metalloproteinases cleave the β2-adrenergic receptor in spontaneously hypertensive rats

(2010) Stephen F. Rodrigues et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Angiotensin II-induced smooth muscle cell migration is mediated by LDL receptor-related protein 1 via regulation of matrix metalloproteinase 2 expression

(2010) Hae Ok Jung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endocytosis unplugged: multiple ways to enter the cell

(2010) Sudha Kumari et al.   CELL RESEARCH

Titin is a Target of Matrix Metalloproteinase-2

(2010) Mohammad A.M. Ali et al.   CIRCULATION

ADAM-17: the enzyme that does it all

(2010) Monika Gooz   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Intracellular substrate cleavage: a novel dimension in the biochemistry, biology and pathology of matrix metalloproteinases

(2010) Bénédicte Cauwe et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Filling Pressures and Collagen Metabolism in Hypertensive Patients With Heart Failure and Normal Ejection Fraction

(2010) Arantxa González et al.   HYPERTENSION

MMP-2 Mediates Angiotensin II–Induced Hypertension Under the Transcriptional Control of MMP-7 and TACE

(2010) Jeffrey Odenbach et al.   HYPERTENSION

Inflammation, Immunity, and Hypertension

(2010) David G. Harrison et al.   HYPERTENSION

Enhanced Matrix Metalloproteinase Activity in the Spontaneously Hypertensive Rat: VEGFR-2 Cleavage, Endothelial Apoptosis, and Capillary Rarefaction

(2010) Edward D. Tran et al.   JOURNAL OF VASCULAR RESEARCH

Matrix metalloproteinases, a disintegrin and metalloproteinases, and a disintegrin and metalloproteinases with thrombospondin motifs in non-neoplastic diseases

(2010) Takayuki Shiomi et al.   PATHOLOGY INTERNATIONAL

ADAM-17 regulates endothelial cell morphology, proliferation, and in vitro angiogenesis

(2009) Pal Göőz et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Proteolytic and non-proteolytic roles of membrane type-1 matrix metalloproteinase in malignancy

(2009) Alex Y. Strongin   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Avoiding spam in the proteolytic internet: Future strategies for anti-metastatic MMP inhibition

(2009) Achim Krüger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Matrix metalloproteinases: What do they not do? New substrates and biological roles identified by murine models and proteomics

(2009) David Rodríguez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Low-Density Lipoprotein Receptor-Related Protein 1 Promotes Cancer Cell Migration and Invasion by Inducing the Expression of Matrix Metalloproteinases 2 and 9

(2009) H. Song et al.   CANCER RESEARCH

Maintenance of adrenergic vascular tone by MMP transactivation of the EGFR requires PI3K and mitochondrial ATP synthesis

(2009) Prabhakara Reddy Nagareddy et al.   CARDIOVASCULAR RESEARCH

Upregulation of Matrix Metalloproteinase-2 in the Arterial Vasculature Contributes to Stiffening and Vasomotor Dysfunction in Patients With Chronic Kidney Disease

(2009) Ada W.Y. Chung et al.   CIRCULATION

Matrix Metalloproteinase-7 and ADAM-12 (a Disintegrin and Metalloproteinase-12) Define a Signaling Axis in Agonist-Induced Hypertension and Cardiac Hypertrophy

(2009) Xiang Wang et al.   CIRCULATION

Matrix Metalloproteinases: Discrete Elevations in Essential Hypertension and Hypertensive End-Stage Renal Disease

(2009) Ryan S. Friese et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

Multiple Roles of the Extracellular Matrix in Inflammation

(2009) E. Korpos et al.   CURRENT PHARMACEUTICAL DESIGN

Serum levels of large tenascin-C variants, matrix metalloproteinase-9, and tissue inhibitors of matrix metalloproteinases in concentric versus eccentric left ventricular hypertrophy

(2009) Marcus Franz et al.   EUROPEAN JOURNAL OF HEART FAILURE

Tumor Necrosis Factor-α–Converting Enzyme Is a Key Regulator of Agonist-Induced Cardiac Hypertrophy and Fibrosis

(2009) Xiang Wang et al.   HYPERTENSION

Extracellular matrix alterations in hypertensive vascular remodeling

(2009) Catherine A. Lemarié et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

LRP1 shedding in human brain: roles of ADAM10 and ADAM17

(2009) Qiang Liu et al.   Molecular Neurodegeneration

Chronic doxycycline exposure accelerates left ventricular hypertrophy and progression to heart failure in mice after thoracic aorta constriction

(2008) Laurent Vinet et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Urokinase directly activates matrix metalloproteinases-9: A potential role in glioblastoma invasion

(2008) Yunge Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Long-Term Doxycycline Is More Effective Than Atenolol to Prevent Thoracic Aortic Aneurysm in Marfan Syndrome Through the Inhibition of Matrix Metalloproteinase-2 and -9

(2008) Ada W.Y. Chung et al.   CIRCULATION RESEARCH

Serum levels of MMP-9 and TIMP-1 in primary hypertension and effect of antihypertensive treatment

(2008) Ibrahim Koral Onal et al.   European Journal of Internal Medicine

The use and safety of doxycycline hyclate and other second-generation tetracyclines

(2008) Barry Sloan et al.   Expert Opinion On Drug Safety

Peroxynitrite inactivates human-tissue inhibitor of metalloproteinase-4

(2008) Sandra Donnini et al.   FEBS LETTERS

Proteinase Activity and Receptor Cleavage

(2008) Frank A. DeLano et al.   HYPERTENSION

Atorvastatin Slows the Progression of Cardiac Remodeling in Mice with Pressure Overload and Inhibits Epidermal Growth Factor Receptor Activation

(2008) Yulin LIAO et al.   HYPERTENSION RESEARCH

Transgenic Expression of Matrix Metalloproteinase-1 Inhibits Myocardial Fibrosis and Prevents the Transition to Heart Failure in a Pressure Overload Mouse Model

(2008) Robert F Foronjy et al.   HYPERTENSION RESEARCH

Cellular roles of ADAM12 in health and disease

(2008) Marie Kveiborg et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Hemopexin Domain of Matrix Metalloproteinase-9 Activates Cell Signaling and Promotes Migration of Schwann Cells by Binding to Low-Density Lipoprotein Receptor-Related Protein

(2008) E. Mantuano et al.   JOURNAL OF NEUROSCIENCE

Protease proteomics: Revealing protease in vivo functions using systems biology approaches

(2008) A DOUCET et al.   MOLECULAR ASPECTS OF MEDICINE

The ADAM metalloproteinases

(2008) D EDWARDS et al.   MOLECULAR ASPECTS OF MEDICINE

LDL Receptor-Related Protein 1: Unique Tissue-Specific Functions Revealed by Selective Gene Knockout Studies

(2008) Anna P. Lillis et al.   PHYSIOLOGICAL REVIEWS

Oleic acid content is responsible for the reduction in blood pressure induced by olive oil

(2008) S. Teres et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cleavage and functional loss of human apolipoprotein E by digestion of matrix metalloproteinase-14

(2008) Jun Hyoung Park et al.   PROTEOMICS

Metalloproteinase inhibition ameliorates hypertension and prevents vascular dysfunction and remodeling in renovascular hypertensive rats

(2007) Michele M. Castro et al.   ATHEROSCLEROSIS

Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease

(2007) Joseph D. Raffetto et al.   BIOCHEMICAL PHARMACOLOGY

Should We Target the Sympathetic Nervous System in the Treatment of Obesity-Associated Hypertension?

(2007) Italo Biaggioni   HYPERTENSION