Journal
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
Volume 23, Issue 5, Pages 583-594Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jvir.2012.01.057
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Pancreatic islet cell transplantation is a promising cellular-based therapy for type I diabetes mellitus. This procedure involves portal venous injection of islet cells and affords I-year insulin independence in as many as 80% of recipients. Although transplant surgeons represent historical drivers of islet therapy, requirement for image guidance and transcatheter techniques has fostered collaboration with interventional radiologists, who are positioned to play a significant role in clinical performance of islet transplantation and in basic science research in this field. This review article aims to familiarize interventional radiologists with islet cell transplantation patient selection, procedure technique, clinical outcomes, and future clinical and research avenues.
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