Review
Medicine, General & Internal
Pau Sarrio-Sanz, Laura Martinez-Cayuelas, Blanca Lumberas, Laura Sanchez-Caballero, Antonio Palazon-Bru, Vicente F. Gil-Guillen, Luis Gomez-Perez
Summary: This study aimed to identify risk-predictive models for bladder-specific cancer mortality in patients undergoing radical cystectomy and assess their clinical utility and risk of bias. The findings showed that clinical predictors can be used to assess the risk of bladder-specific cancer mortality, but the studies had a high risk of bias and their applicability is uncertain.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2022)
Review
Cardiac & Cardiovascular Systems
Liang-Liang Hu, Zhong-Qiang Guo, Peng Dai, Gang Chen, Tao Tian
Summary: Pheochromocytomas are rare neuroendocrine tumors that produce catecholamines. Bladder involvement is uncommon, and common symptoms include hypertension, headache, hematuria, and syncope. While transurethral resection may be performed in some patients, most require partial or radical cystectomy.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, General & Internal
Kuo-Wei Kao, Weiming Cheng, Yi-Chin Chang
Summary: Bladder chondroma is a rare benign tumor that mainly affects older patients. It manifests as urinary symptoms and abdominal pain, and transurethral resection is the preferred treatment.
Article
Urology & Nephrology
Avril Lusty, R. Christopher Doiron, Christopher M. Booth, Marlo Whitehead, D. Robert Siemens
Summary: The study aimed to compare the survival outcomes of patients with muscle-invasive bladder cancer, and found that after adjustment, there were no clinically significant differences in survival rates between de novo cases and progressors undergoing radical cystectomy.
JOURNAL OF UROLOGY
(2021)
Article
Urology & Nephrology
Alberto Martini, Luca Afferi, Stefania Zamboni, Julianne G. Schultz, Chiara Lonati, Agostino Mattei, R. Jeffrey Karnes, Matteo Soligo, Armando Stabile, Ettore Di Trapani, Ottavio De Cobelli, Giuseppe Simone, Claudio Simeone, Mario Alvarez-Maestro, Giorgio Gandaglia, Andrea Gallina, Renzo Colombo, Alberto Briganti, Francesco Montorsi, Evanguelos Xylinas, Shahrokh F. Shariat, Marco Moschini
Summary: The study found that patients with variant histology bladder cancer have a higher risk of recurrence, requiring extended surveillance time, and different histological types have different risks of recurrence and metastasis.
JOURNAL OF UROLOGY
(2021)
Article
Oncology
Eunhye Yi, Yang-Sook Yoo, Sunhee Lee, Hanjong Park
Summary: This study aims to understand the experiences of illness among bladder cancer patients in Korea after radical cystectomy. Through interviews, six themes were derived, representing the emotional state and adaptation process after surgery.
Article
Oncology
Frederik Wessels, Isabelle Bussoff, Sophia Adam, Karl-Friedrich Kowalewski, Manuel Neuberger, Philipp Nuhn, Maurice S. Michel, Maximilian C. Kriegmair
Summary: This study evaluated the ability of comorbidity indices and their combination with clinical parameters in machine learning models to predict mortality and morbidity after radical cystectomy (RC). The results showed that certain comorbidity indices had significant predictive value for complications and mortality, but performed well only in predicting mortality. Combining clinical parameters in machine learning models improved the prediction accuracy.
Article
Urology & Nephrology
Francesco Alessandro Mistretta, Gennaro Musi, Claudia Colla Ruvolo, Andrea Conti, Stefano Luzzago, Michele Catellani, Ettore Di Trapani, Gabriele Cozzi, Roberto Bianchi, Matteo Ferro, Antonio Cioffi, Giovanni Cordima, Antonio Brescia, Fabrizio Verweij, Danilo Bottero, Deliu Victor Matei, Vincenzo Mirone, Ottavio De Cobelli
Summary: The study compared the outcomes and complication rates between ICNB and ECNB in patients, and found no statistically significant differences in surgical, oncologic, and functional outcomes as well as complication rates between the two methods.
JOURNAL OF ENDOUROLOGY
(2021)
Article
Urology & Nephrology
Victor M. Schuettfort, Kilian Gust, David D'Andrea, Fahad Quhal, Hadi Mostafaei, Ekaterina Laukhtina, Keiichiro Mori, Michael Rink, Mohammad Abufaraj, Pierre Karakiewicz, Stefano Luzzago, Morgan Roupret, Dmitry Enikeev, Kristin Zimmermann, Marina Deuker, Marco Moschini, Reza Sari Motlagh, Nico C. Grossmann, Satoshi Katayama, Benjamin Pradere, Shahrokh F. Shariat
Summary: This study confirmed the predictive and prognostic value of the preoperative modified Glasgow Prognostic Score (mGPS) in patients with UCB undergoing RC, showing its independent risk factor for non-organ confined disease and poor survival outcomes. However, the mGPS demonstrated limited value in enhancing the discriminatory ability of predictive and prognostic models that relied on either pre- or postoperative clinicopathological variables. Further evaluation of the mGPS in the era of immunotherapy is warranted.
MINERVA UROLOGY AND NEPHROLOGY
(2022)
Article
Urology & Nephrology
Riccardo Mastroianni, Mariaconsiglia Ferriero, Gabriele Tuderti, Umberto Anceschi, Alfredo Maria Bove, Aldo Brassetti, Leonardo Misuraca, Ashanti Zampa, Giulia Torregiani, Edoardo Ghiani, Diana Giannarelli, Salvatore Guaglianone, Michele Gallucci, Giuseppe Simone
Summary: This study compared perioperative and 6-month outcomes between open radical cystectomy (ORC) and robot-assisted radical cystectomy (RARC) with totally intracorporeal urinary diversion (UD). Results showed that RARC with intracorporeal UD had a significantly lower overall perioperative transfusion rate compared to ORC. However, perioperative complications, hospital stay, and 6-month health-related quality of life were similar between the two groups. Long-term follow-up is needed to assess oncologic and functional outcomes.
JOURNAL OF UROLOGY
(2022)
Article
Medical Laboratory Technology
Polat Turker, Mona-Lisa Wernroth, Per-Uno Malmstrom, Ulrika Segersten, Tammer Hemdan
Summary: A study demonstrated that CCTa biomarker could serve as a predictive tool for guiding the efficacy of neoadjuvant chemotherapy in bladder cancer patients, while the predictive value of other biomarkers was limited. Combining CCTa with other biomarkers might enhance the predictive ability of NAC efficacy in patients, potentially reducing the number needed to treat.
TRANSLATIONAL RESEARCH
(2021)
Article
Pediatrics
Sherif M. El-Desoky, Mai Banakhar, Khalid Khashoggi, Zaher Faisal Zaher, Amr S. Albanna, Jameela A. Kari
Summary: This study found that the survival rate and morbidity of bladder dysfunction in children are significantly influenced by factors such as the etiology of the dysfunction, baseline glomerular filtration rate, and age at presentation.
INDIAN JOURNAL OF PEDIATRICS
(2022)
Article
Oncology
Yinmeng Hou, Yiqian Chen, Shicong Lai, Samuel Seery, Ling Wang, Xiaodan Li, Huixin Liu, Caipeng Qin, Wei Li, Xiangyun Lu, Chunxia Liu, Jia Wang, Tao Xu
Summary: This study aims to explore decision regret after cystectomy among Chinese bladder cancer patients. The results indicate that decision regret is associated with decision conflict, quality of life, and perceptions of others' quality of life.
Article
Urology & Nephrology
Abhinav Khanna, Tanner Miest, Vidit Sharma, Rebecca Campbell, Patrick Hensley, Prabin Thapa, Andrew Zganjar, Matthew K. Tollefson, R. Houston Thompson, Igor Frank, R. J. Karnes, Prithvi B. Murthy, Georges P. Haber, Neema Navai, Ashish M. Kamat, Colin Dinney, Byron Lee, Stephen A. Boorjian
Summary: This study aimed to assess the association between the extent of lymph node dissection (LND) during radical cystectomy (RC) for nonmuscle-invasive bladder cancer (NMIBC) and survival outcomes. The results showed that a greater extent of LND was associated with improved local pelvic recurrence-free survival (LPRS), cancer-specific survival (CSS), and overall survival (OS). This suggests that the inclusion of LND in the treatment of NMIBC can enhance patient prognosis.
JOURNAL OF UROLOGY
(2022)
Article
Urology & Nephrology
Firas G. Petros, Woonyoung Choi, Yuan Qi, Tyler Moss, Roger Li, Xiaoping Su, Charles C. Guo, Bogdan Czerniak, Colin Dinney, David J. McConkey, Surena F. Matin
Summary: This study compared different types of urothelial carcinoma in the same patient and found that differences in gene expression may be associated with pathological features. Metachronous tumors largely maintained the molecular subtype membership of the initial tumor.
JOURNAL OF UROLOGY
(2021)