A site of varicella-zoster virus vulnerability identified by structural studies of neutralizing antibodies bound to the glycoprotein complex gHgL

Proof of principle for epitope-focused vaccine design

(2014) Bruno E. Correia et al.   NATURE

Molecular mechanisms of varicella zoster virus pathogenesis

(2014) Leigh Zerboni et al.   NATURE REVIEWS MICROBIOLOGY

The Cytoplasmic Domain of Varicella-Zoster Virus Glycoprotein H Regulates Syncytia Formation and Skin Pathogenesis

(2014) Edward Yang et al.   PLoS Pathogens

Cytomegalovirus vaccine: phase II clinical trial results

(2013) F. Rieder et al.   CLINICAL MICROBIOLOGY AND INFECTION

The Large Groove Found in the gH/gL Structure Is an Important Functional Domain for Epstein-Barr Virus Fusion

(2013) J. Chen et al.   JOURNAL OF VIROLOGY

An immunoreceptor tyrosine-based inhibition motif in varicella-zoster virus glycoprotein B regulates cell fusion and skin pathogenesis

(2013) S. L. Oliver et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alphaherpesvirinae and Gammaherpesvirinae glycoprotein L and CMV UL130 originate from chemokines

(2013) Maja Malkowska et al.   Virology Journal

Regulation of Herpes Simplex Virus gB-Induced Cell-Cell Fusion by Mutant Forms of gH/gL in the Absence of gD and Cellular Receptors

(2013) D. Atanasiu et al.   mBio

A Phase 1/2 Clinical Trial Evaluating Safety and Immunogenicity of a Varicella Zoster Glycoprotein E Subunit Vaccine Candidate in Young and Older Adults

(2012) Isabel Leroux-Roels et al.   JOURNAL OF INFECTIOUS DISEASES

Human Anti-Varicella-Zoster Virus (VZV) Recombinant Monoclonal Antibody Produced after Zostavax Immunization Recognizes the gH/gL Complex and Neutralizes VZV Infection

(2012) M. Birlea et al.   JOURNAL OF VIROLOGY

Structure-function analysis of varicella-zoster virus glycoprotein H identifies domain-specific roles for fusion and skin tropism

(2011) S. E. Vleck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of the conserved herpesvirus fusion regulator complex gH–gL

(2010) Tirumala K Chowdary et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structure of the Epstein-Barr virus (EBV) glycoprotein H/glycoprotein L (gH/gL) complex

(2010) H. Matsuura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of a core fragment of glycoprotein H from pseudorabies virus in complex with antibody

(2010) M. Backovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cross Talk among the Glycoproteins Involved in Herpes Simplex Virus Entry and Fusion: the Interaction between gB and gH/gL Does Not Necessarily Require gD

(2009) E. Avitabile et al.   JOURNAL OF VIROLOGY

Functional Analysis of Glycoprotein L (gL) from Rhesus Lymphocryptovirus in Epstein-Barr Virus-Mediated Cell Fusion Indicates a Direct Role of gL in gB-Induced Membrane Fusion

(2009) A. E. Plate et al.   JOURNAL OF VIROLOGY

Anti-Glycoprotein H Antibody Impairs the Pathogenicity of Varicella-Zoster Virus in Skin Xenografts in the SCID Mouse Model

(2009) S. E. Vleck et al.   JOURNAL OF VIROLOGY

Myelin-associated glycoprotein mediates membrane fusion and entry of neurotropic herpesviruses

(2009) T. Suenaga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of a trimeric variant of the Epstein–Barr virus glycoprotein B

(2009) Marija Backovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of Neutralizing Epitopes of Varicella-Zoster Virus Glycoprotein H

(2008) Y. Akahori et al.   JOURNAL OF VIROLOGY