Structural asymmetry in a conserved signaling system that regulates division, replication, and virulence of an intracellular pathogen

The CtrA phosphorelay integrates differentiation and communication in the marine alphaproteobacterium Dinoroseobacter shibae

(2014) Hui Wang et al.   BMC GENOMICS

TheBrucella abortusvirulence regulator, LovhK, is a sensor kinase in the general stress response signalling pathway

(2014) Hye-Sook Kim et al.   MOLECULAR MICROBIOLOGY

Global analysis of cell cycle gene expression of the legume symbiontSinorhizobium meliloti

(2014) Nicole J. De Nisco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell cycle-dependent adaptor complex for ClpXP-mediated proteolysis directly integrates phosphorylation and second messenger signals

(2014) Stephen C. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Visualizing autophosphorylation in histidine kinases

(2014) Patricia Casino et al.   Nature Communications

Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation

(2014) Ariel E. Mechaly et al.   PLOS BIOLOGY

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

(2013) Sander Pronk et al.   BIOINFORMATICS

Determinants of specificity in two-component signal transduction

(2013) Anna I Podgornaia et al.   CURRENT OPINION IN MICROBIOLOGY

myo-Inositol and D-Ribose Ligand Discrimination in an ABC Periplasmic Binding Protein

(2013) J. Herrou et al.   JOURNAL OF BACTERIOLOGY

TheBrucella abortusGeneral Stress Response System Regulates Chronic Mammalian Infection and Is Controlled by Phosphorylation and Proteolysis

(2013) Hye-Sook Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordination of Division and Development Influences Complex Multicellular Behavior in Agrobacterium tumefaciens

(2013) Jinwoo Kim et al.   PLoS One

The CckA-ChpT-CtrA Phosphorelay System Is Regulated by Quorum Sensing and Controls Flagellar Motility in the Marine Sponge Symbiont Ruegeria sp. KLH11

(2013) Jindong Zan et al.   PLoS One

Full-Length Structure of a Sensor Histidine Kinase Pinpoints Coaxial Coiled Coils as Signal Transducers and Modulators

(2013) Ralph P. Diensthuber et al.   STRUCTURE

Branched Signal Wiring of an Essential Bacterial Cell-Cycle Phosphotransfer Protein

(2013) Jimmy A. Blair et al.   STRUCTURE

Specificity Residues Determine Binding Affinity for Two-Component Signal Transduction Systems

(2013) J. W. Willett et al.   mBio

Mechanistic Insights Revealed by the Crystal Structure of a Histidine Kinase with Signal Transducer and Sensor Domains

(2013) Chen Wang et al.   PLOS BIOLOGY

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

Structural insights into ChpT, an essential dimeric histidine phosphotransferase regulating the cell cycle inCaulobacter crescentus

(2012) Antonella Fioravanti et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Evolution of Two-Component Signal Transduction Systems

(2012) Emily J. Capra et al.   Annual Review of Microbiology

Polarity and cell fate asymmetry in Caulobacter crescentus

(2012) Christos G Tsokos et al.   CURRENT OPINION IN MICROBIOLOGY

Transcriptional regulation of the Rhodobacter capsulatus response regulator CtrA

(2012) M. M. Leung et al.   MICROBIOLOGY-SGM

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Structural basis of a protein partner switch that regulates the general stress response of  -proteobacteria

(2012) J. Herrou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polar growth in the Alphaproteobacterial order Rhizobiales

(2012) P. J. B. Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic and Biochemical Dissection of a HisKA Domain Identifies Residues Required Exclusively for Kinase and Phosphatase Activities

(2012) Jonathan W. Willett et al.   PLoS Genetics

Clinical Manifestations of Human Brucellosis: A Systematic Review and Meta-Analysis

(2012) Anna S. Dean et al.   PLoS Neglected Tropical Diseases

CrdS and CrdA Comprise a Two-Component System That Is Cooperatively Regulated by the Che3 Chemosensory System in Myxococcus xanthus

(2011) J. W. Willett et al.   mBio

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Interactions of the Human PathogenicBrucellaSpecies with Their Hosts

(2010) Vidya L. Atluri et al.   Annual Review of Microbiology

Electronic and Protein Structural Dynamics of a Photosensory Histidine Kinase

(2010) Maxime T. A. Alexandre et al.   BIOCHEMISTRY

The diversity and evolution of cell cycle regulation in alpha-proteobacteria: a comparative genomic analysis

(2010) Matteo Brilli et al.   BMC Systems Biology

Kinetic Characterization of the WalRKSpn (VicRK) Two-Component System of Streptococcus pneumoniae: Dependence of WalKSpn (VicK) Phosphatase Activity on Its PAS Domain

(2010) A. D. Gutu et al.   JOURNAL OF BACTERIOLOGY

The ecological coherence of high bacterial taxonomic ranks

(2010) Laurent Philippot et al.   NATURE REVIEWS MICROBIOLOGY

Improved side-chain torsion potentials for the Amber ff99SB protein force field

(2010) Kresten Lindorff-Larsen et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Systematic Dissection and Trajectory-Scanning Mutagenesis of the Molecular Interface That Ensures Specificity of Two-Component Signaling Pathways

(2010) Emily J. Capra et al.   PLoS Genetics

Structural Insight into Partner Specificity and Phosphoryl Transfer in Two-Component Signal Transduction

(2009) Patricia Casino et al.   CELL

System-level design of bacterial cell cycle control

(2009) Harley H. McAdams et al.   FEBS LETTERS

The MiST2 database: a comprehensive genomics resource on microbial signal transduction

(2009) Luke E. Ulrich et al.   NUCLEIC ACIDS RESEARCH

Structural plasticity and catalysis regulation of a thermosensor histidine kinase

(2009) D. Albanesi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Why and How Bacteria Localize Proteins

(2009) L. Shapiro et al.   SCIENCE

Broad-Host-Range Expression Vectors with Tightly Regulated Promoters and Their Use To Examine the Influence of TraR and TraM Expression on Ti Plasmid Quorum Sensing

(2008) S. R. Khan et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Rewiring the Specificity of Two-Component Signal Transduction Systems

(2008) Jeffrey M. Skerker et al.   CELL

An Improved Cryogen for Plunge Freezing

(2008) William F. Tivol et al.   MICROSCOPY AND MICROANALYSIS