Structural insights into mis-regulation of protein kinase A in human tumors

Genomic analysis of fibrolamellar hepatocellular carcinoma

(2014) Lei Xu et al.   HUMAN MOLECULAR GENETICS

Recurrent activating mutation in PRKACA in cortisol-producing adrenal tumors

(2014) Gerald Goh et al.   NATURE GENETICS

Constitutive Activation of PKA Catalytic Subunit in Adrenal Cushing's Syndrome

(2014) Felix Beuschlein et al.   NEW ENGLAND JOURNAL OF MEDICINE

Activating hotspot L205R mutation in PRKACA and adrenal Cushing's syndrome

(2014) Y. Cao et al.   SCIENCE

Detection of a Recurrent DNAJB1-PRKACA Chimeric Transcript in Fibrolamellar Hepatocellular Carcinoma

(2014) J. N. Honeyman et al.   SCIENCE

Recurrent somatic mutations underlie corticotropin-independent Cushing's syndrome

(2014) Y. Sato et al.   SCIENCE

Combining crystallography and EPR: crystal and solution structures of the multidomain cochaperone DnaJ

(2013) Thomas R. M. Barends et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Localization and quaternary structure of the PKA RI  holoenzyme

(2012) R. Ilouz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Allostery of the PKA RII  Tetrameric Holoenzyme

(2012) P. Zhang et al.   SCIENCE

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A Myristoyl/Phosphoserine Switch Controls cAMP-Dependent Protein Kinase Association to Membranes

(2011) Ece C. Gaffarogullari et al.   JOURNAL OF MOLECULAR BIOLOGY

Phosphatase-Coupled Universal Kinase Assay and Kinetics for First-Order-Rate Coupling Reaction

(2011) Zhengliang L. Wu   PLoS One

Realizing the Allosteric Potential of the Tetrameric Protein Kinase A RIα Holoenzyme

(2011) Angela J. Boettcher et al.   STRUCTURE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A-kinase-interacting Protein 1 (AKIP1) Acts as a Molecular Determinant of PKA in NF-κB Signaling

(2010) Nan Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How does cAMP/protein kinase A signaling lead to tumors in the adrenal cortex and other tissues?

(2010) Madson Q. Almeida et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Novel Isoform-Specific Interfaces Revealed by PKA RIIβ Holoenzyme Structures

(2009) Simon H.J. Brown et al.   JOURNAL OF MOLECULAR BIOLOGY