Genetic analysis of the contribution of LTBP-3 to thoracic aneurysm in Marfan syndrome

Dimorphic Effects of Transforming Growth Factor-β Signaling During Aortic Aneurysm Progression in Mice Suggest a Combinatorial Therapy for Marfan SyndromeSignificance

(2015) Jason R. Cook et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Latent TGF-β binding protein-2 is essential for the development of ciliary zonule microfibrils

(2014) Tadashi Inoue et al.   HUMAN MOLECULAR GENETICS

Function of Latent TGFβ Binding Protein 4 and Fibulin 5 in Elastogenesis and Lung Development

(2014) Branka Dabovic et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis

(2014) Wei Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanotransduction and extracellular matrix homeostasis

(2014) Jay D. Humphrey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TGF-β Activation and Function in Immunity

(2013) Mark A. Travis et al.   Annual Review of Immunology

Angiotensin II–dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis

(2013) Elena M. Gallo et al.   JOURNAL OF CLINICAL INVESTIGATION

GM-CSF contributes to aortic aneurysms resulting from SMAD3 deficiency

(2013) Ping Ye et al.   JOURNAL OF CLINICAL INVESTIGATION

The fibrillin-1 hypomorphic mgR/mgR murine model of Marfan syndrome shows severe elastolysis in all segments of the aorta

(2013) Simon Schwill et al.   JOURNAL OF VASCULAR SURGERY

Latent TGF-  binding protein 4 promotes elastic fiber assembly by interacting with fibulin-5

(2013) K. Noda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MMP-2 Regulates Erk1/2 Phosphorylation and Aortic Dilatation in Marfan Syndrome

(2012) Wanfen Xiong et al.   CIRCULATION RESEARCH

Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis

(2012) Laura S. Danielson et al.   FASEB JOURNAL

Matrix-dependent perturbation of TGFβ signaling and disease

(2012) Jefferson J. Doyle et al.   FEBS LETTERS

Specificity of latent TGF-β binding protein (LTBP) incorporation into matrix: Role of fibrillins and fibronectin

(2012) Lior Zilberberg et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Loss-of-function mutations in TGFB2 cause a syndromic presentation of thoracic aortic aneurysm

(2012) Mark E Lindsay et al.   NATURE GENETICS

TGFB2 mutations cause familial thoracic aortic aneurysms and dissections associated with mild systemic features of Marfan syndrome

(2012) Catherine Boileau et al.   NATURE GENETICS

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Noncanonical TGF  Signaling Contributes to Aortic Aneurysm Progression in Marfan Syndrome Mice

(2011) T. M. Holm et al.   SCIENCE

Angiotensin II Type 2 Receptor Signaling Attenuates Aortic Aneurysm in Mice Through ERK Antagonism

(2011) J. P. Habashi et al.   SCIENCE

Absence of TGFβ signaling in embryonic vascular smooth muscle leads to reduced lysyl oxidase expression, impaired elastogenesis, and aneurysm

(2009) Bibha Choudhary et al.   GENESIS

Perturbation of transforming growth factor (TGF)-ss1 association with latent TGF-  binding protein yields inflammation and tumors

(2008) K. Yoshinaga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA