Screening for tumor suppressors: Loss of ephrin receptor A2 cooperates with oncogenicKRasin promoting lung adenocarcinoma
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Title
Screening for tumor suppressors: Loss of ephrin receptor A2 cooperates with oncogenicKRasin promoting lung adenocarcinoma
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 112, Issue 47, Pages E6476-E6485
Publisher
Proceedings of the National Academy of Sciences
Online
2015-11-06
DOI
10.1073/pnas.1520110112
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Note: Only part of the references are listed.- Eph Receptors and Ephrins: Therapeutic Opportunities
- (2015) Antonio Barquilla et al. Annual Review of Pharmacology and Toxicology
- Cancer statistics, 2015
- (2015) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Proteolysis of EphA2 Converts It from a Tumor Suppressor to an Oncoprotein
- (2015) N. Koshikawa et al. CANCER RESEARCH
- Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis
- (2015) Sidi Chen et al. CELL
- Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
- (2015) Silvana Konermann et al. NATURE
- Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis
- (2015) Zhen Zhao et al. NATURE GENETICS
- How do K-RAS-activated cells evade cellular defense mechanisms?
- (2015) Y-S Lee et al. ONCOGENE
- EphB6 promotes anoikis by modulating EphA2 signaling
- (2014) Mai Akada et al. CELLULAR SIGNALLING
- Genetic and pharmacologic inhibition of EPHA2 promotes apoptosis in NSCLC
- (2014) Katherine R. Amato et al. JOURNAL OF CLINICAL INVESTIGATION
- Comprehensive molecular profiling of lung adenocarcinoma
- (2014) Eric A. Collisson et al. NATURE
- Rapid modelling of cooperating genetic events in cancer through somatic genome editing
- (2014) Francisco J. Sánchez-Rivera et al. NATURE
- In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer
- (2014) Ramona Rudalska et al. NATURE MEDICINE
- In vivo shRNA screens in solid tumors
- (2014) Gaetano Gargiulo et al. Nature Protocols
- EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties
- (2014) H Miao et al. ONCOGENE
- Direct in Vivo RNAi Screen Unveils Myosin IIa as a Tumor Suppressor of Squamous Cell Carcinomas
- (2014) D. Schramek et al. SCIENCE
- Sleeping Beauty mutagenesis: exploiting forward genetic screens for cancer gene discovery
- (2013) Michael B Mann et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- EphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion
- (2013) Nami Sugiyama et al. JOURNAL OF CELL BIOLOGY
- Mouse models for lung cancer
- (2013) Min-chul Kwon et al. Molecular Oncology
- RNAi screens in mice identify physiological regulators of oncogenic growth
- (2013) Slobodan Beronja et al. NATURE
- Unraveling the therapeutic potential of the Hedgehog pathway in cancer
- (2013) Dereck Amakye et al. NATURE MEDICINE
- The mechanisms of Hedgehog signalling and its roles in development and disease
- (2013) James Briscoe et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Gli1 Mediates Lung Cancer Cell Proliferation and Sonic Hedgehog-Dependent Mesenchymal Cell Activation
- (2013) Olga Bermudez et al. PLoS One
- Eph Receptor Signaling and Ephrins
- (2013) E. M. Lisabeth et al. Cold Spring Harbor Perspectives in Biology
- Ephexin4-mediated promotion of cell migration and anoikis resistance is regulated by serine 897 phosphorylation of EphA2
- (2013) Hiromu Kawai et al. FEBS Open Bio
- The GATA2 Transcriptional Network Is Requisite for RAS Oncogene-Driven Non-Small Cell Lung Cancer
- (2012) Madhu S. Kumar et al. CELL
- Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing
- (2012) Marcin Imielinski et al. CELL
- Higher expression of EphA2 and ephrin-A1 is related to favorable clinicopathological features in pathological stage I non-small cell lung carcinoma
- (2012) Masashi Ishikawa et al. LUNG CANCER
- Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model
- (2012) Yifeng Xia et al. NATURE CELL BIOLOGY
- A Small Molecule Agonist of EphA2 Receptor Tyrosine Kinase Inhibits Tumor Cell Migration In Vitro and Prostate Cancer Metastasis In Vivo
- (2012) Aaron Petty et al. PLoS One
- Oncogenic and Wild-type Ras Play Divergent Roles in the Regulation of Mitogen-Activated Protein Kinase Signaling
- (2012) Amy Young et al. Cancer Discovery
- Ephexin4 and EphA2 mediate resistance to anoikis through RhoG and phosphatidylinositol 3-kinase
- (2011) Kohei Harada et al. EXPERIMENTAL CELL RESEARCH
- Identification of ER Proteins Involved in the Functional Organisation of the Early Secretory Pathway in Drosophila Cells by a Targeted RNAi Screen
- (2011) Vangelis Kondylis et al. PLoS One
- Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism
- (2010) Nao Hiramoto-Yamaki et al. JOURNAL OF CELL BIOLOGY
- Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models
- (2010) Silvestre Vicent et al. JOURNAL OF CLINICAL INVESTIGATION
- Stage-specific sensitivity to p53 restoration during lung cancer progression
- (2010) David M. Feldser et al. NATURE
- EphA2 Mediates Ligand-Dependent Inhibition and Ligand-Independent Promotion of Cell Migration and Invasion via a Reciprocal Regulatory Loop with Akt
- (2009) Hui Miao et al. CANCER CELL
- Expression of the Receptor Tyrosine Kinase EphA2 Is Increased in Smokers and Predicts Poor Survival in Non-Small Cell Lung Cancer
- (2009) J. M. Brannan et al. CLINICAL CANCER RESEARCH
- Positive- and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway
- (2009) S.-Y. Shin et al. JOURNAL OF CELL SCIENCE
- Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase
- (2009) Michel DuPage et al. Nature Protocols
- Pten Inactivation Accelerates Oncogenic K-ras-Initiated Tumorigenesis in a Mouse Model of Lung Cancer
- (2008) K. Iwanaga et al. CANCER RESEARCH
- Somatic mutations affect key pathways in lung adenocarcinoma
- (2008) Li Ding et al. NATURE
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