Essential roles of methionine andS-adenosylmethionine in the autarkic lifestyle ofMycobacterium tuberculosis

Target-Based Identification of Whole-Cell Active Inhibitors of Biotin Biosynthesis in Mycobacterium tuberculosis

(2015) Sae Woong Park et al.   CHEMISTRY & BIOLOGY

Methionine Metabolism Regulates Maintenance and Differentiation of Human Pluripotent Stem Cells

(2014) Nobuaki Shiraki et al.   Cell Metabolism

Folate Pathway Disruption Leads to Critical Disruption of Methionine Derivatives in Mycobacterium tuberculosis

(2014) Molly R. Nixon et al.   CHEMISTRY & BIOLOGY

Specialized Transduction Designed for Precise High-Throughput Unmarked Deletions in Mycobacterium tuberculosis

(2014) P. Jain et al.   mBio

Isocitrate lyase mediates broad antibiotic tolerance in Mycobacterium tuberculosis

(2014) Madhumitha Nandakumar et al.   Nature Communications

Mycobacterium tuberculosis Exploits Asparagine to Assimilate Nitrogen and Resist Acid Stress during Infection

(2014) Alexandre Gouzy et al.   PLoS Pathogens

Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing

(2013) Yanjia J. Zhang et al.   CELL

Sulfur Amino Acids Regulate Translational Capacity and Metabolic Homeostasis through Modulation of tRNA Thiolation

(2013) Sunil Laxman et al.   CELL

Methionine Inhibits Autophagy and Promotes Growth by Inducing the SAM-Responsive Methylation of PP2A

(2013) Benjamin M. Sutter et al.   CELL

Feast or famine: the host-pathogen battle over amino acids

(2013) Yanjia J. Zhang et al.   CELLULAR MICROBIOLOGY

Mycobacterium tuberculosis nitrogen assimilation and host colonization require aspartate

(2013) Alexandre Gouzy et al.   Nature Chemical Biology

Global methylation state at base-pair resolution of the Caulobacter genome throughout the cell cycle

(2013) J. B. Kozdon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of homocysteine metabolism by Mycobacterium tuberculosis S-adenosylhomocysteine hydrolase

(2013) Anshika Singhal et al.   Scientific Reports

Francisella tularensis Harvests Nutrients Derived via ATG5-Independent Autophagy to Support Intracellular Growth

(2013) Shaun Steele et al.   PLoS Pathogens

DNA Methylation Impacts Gene Expression and Ensures Hypoxic Survival of Mycobacterium tuberculosis

(2013) Scarlet S. Shell et al.   PLoS Pathogens

Amino Acid Starvation Induced by Invasive Bacterial Pathogens Triggers an Innate Host Defense Program

(2012) Ivan Tattoli et al.   Cell Host & Microbe

Discovery of Selective Menaquinone Biosynthesis Inhibitors against Mycobacterium tuberculosis

(2012) Joy Debnath et al.   JOURNAL OF MEDICINAL CHEMISTRY

Impact of methylations of m2G966/m5C967 in 16S rRNA on bacterial fitness and translation initiation

(2012) Dmitry E. Burakovsky et al.   NUCLEIC ACIDS RESEARCH

In vitro differentiation of human macrophages with enhanced antimycobacterial activity

(2011) Guillaume Vogt et al.   JOURNAL OF CLINICAL INVESTIGATION

Evaluating the Sensitivity of Mycobacterium tuberculosis to Biotin Deprivation Using Regulated Gene Expression

(2011) Sae Woong Park et al.   PLoS Pathogens

Exploitation of conserved eukaryotic host cell farnesylation machinery by an F-box effector ofLegionella pneumophila

(2010) Christopher T.D. Price et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NAD+auxotrophy is bacteriocidal for the tubercle bacilli

(2010) Catherine Vilchèze et al.   MOLECULAR MICROBIOLOGY

Vitamin B6 biosynthesis is essential for survival and virulence of Mycobacterium tuberculosis

(2010) Thomas Dick et al.   MOLECULAR MICROBIOLOGY

Methylthioadenosine/S-adenosylhomocysteine nucleosidase, a critical enzyme for bacterial metabolism

(2010) Nikhat Parveen et al.   MOLECULAR MICROBIOLOGY

Direct detection of DNA methylation during single-molecule, real-time sequencing

(2010) Benjamin A Flusberg et al.   NATURE METHODS

Carbon metabolism of intracellular bacterial pathogens and possible links to virulence

(2010) Wolfgang Eisenreich et al.   NATURE REVIEWS MICROBIOLOGY

Unique Flexibility in Energy Metabolism Allows Mycobacteria to Combat Starvation and Hypoxia

(2010) Michael Berney et al.   PLoS One

Mycolic Acid Cyclopropanation is Essential for Viability, Drug Resistance, and Cell Wall Integrity of Mycobacterium tuberculosis

(2009) Daniel Barkan et al.   CHEMISTRY & BIOLOGY

Menaquinone synthesis is critical for maintaining mycobacterial viability during exponential growth and recovery from non-replicating persistence

(2009) Rakesh K. Dhiman et al.   MOLECULAR MICROBIOLOGY

The aptamer core of SAM-IV riboswitches mimics the ligand-binding site of SAM-I riboswitches

(2008) Z. Weinberg et al.   RNA