Poly(ADP-ribose) polymerase 1 is a novel target to promote axonal regeneration

Regulation of NAD biosynthetic enzymes modulates NAD-sensing processes to shape mammalian cell physiology under varying biological cues

(2015) Silverio Ruggieri et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

PARP inhibitors: A new era of targeted therapy

(2015) Shifalika Tangutoori et al.   MATURITAS

NAD+ and SIRT3 control microtubule dynamics and reduce susceptibility to antimicrotubule agents

(2014) W. T. Harkcom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis

(2014) S. A. Andrabi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ARTD1/PARP1 Negatively Regulates Glycolysis by Inhibiting Hexokinase 1 Independent of NAD + Depletion

(2014) Elise Fouquerel et al.   Cell Reports

MicroRNA-138 and SIRT1 form a mutual negative feedback loop to regulate mammalian axon regeneration

(2013) C.-M. Liu et al.   GENES & DEVELOPMENT

Specific Acetylation of p53 by HDAC Inhibition Prevents DNA Damage-Induced Apoptosis in Neurons

(2013) C. Brochier et al.   JOURNAL OF NEUROSCIENCE

HspB1 silences translation of PDZ-RhoGEF by enhancing miR-20a and miR-128 expression to promote neurite extension

(2013) Xiankui Sun et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Chromatin Modifications Associated with DNA Double-strand Breaks Repair as Potential Targets for Neurological Diseases

(2013) Camille Brochier et al.   Neurotherapeutics

Sirtuin Deacetylases as Therapeutic Targets in the Nervous System

(2013) Brett Langley et al.   Neurotherapeutics

Scar-mediated inhibition and CSPG receptors in the CNS

(2012) Kartavya Sharma et al.   EXPERIMENTAL NEUROLOGY

NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans

(2012) Travis L Dickendesher et al.   NATURE NEUROSCIENCE

Functional Complexity of the Axonal Growth Cone: A Proteomic Analysis

(2012) Adriana Estrada-Bernal et al.   PLoS One

Leukocyte Common Antigen-Related Phosphatase Is a Functional Receptor for Chondroitin Sulfate Proteoglycan Axon Growth Inhibitors

(2011) D. Fisher et al.   JOURNAL OF NEUROSCIENCE

Sirt1 overexpression in neurons promotes neurite outgrowth and cell survival through inhibition of the mTOR signaling

(2011) Wenjing Guo et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Poly(ADP-Ribose) (PAR) Binding to Apoptosis-Inducing Factor Is Critical for PAR Polymerase-1-Dependent Cell Death (Parthanatos)

(2011) Y. Wang et al.   Science Signaling

Mitochondria and Neuroplasticity

(2010) Aiwu Cheng et al.   ASN Neuro

PTEN/mTOR and axon regeneration

(2010) Kevin K. Park et al.   EXPERIMENTAL NEUROLOGY

Protein deacetylase SIRT1 in the cytoplasm promotes nerve growth factor-induced neurite outgrowth in PC12 cells

(2010) Toshiya Sugino et al.   FEBS LETTERS

MAG and OMgp Synergize with Nogo-A to Restrict Axonal Growth and Neurological Recovery after Spinal Cord Trauma

(2010) W. B. J. Cafferty et al.   JOURNAL OF NEUROSCIENCE

Long-Distance Axon Regeneration in the Mature Optic Nerve: Contributions of Oncomodulin, cAMP, and pten Gene Deletion

(2010) T. Kurimoto et al.   JOURNAL OF NEUROSCIENCE

PARP1 ADP-ribosylates lysine residues of the core histone tails

(2010) Simon Messner et al.   NUCLEIC ACIDS RESEARCH

Poly(ADP-ribose) signals to mitochondrial AIF: A key event in parthanatos

(2009) Yingfei Wang et al.   EXPERIMENTAL NEUROLOGY

Parthanatos, a messenger of death

(2009) Karen Kate David   Frontiers in Bioscience-Landmark

Nicotinamide Mononucleotide Adenylyltransferase Expression in Mitochondrial Matrix Delays Wallerian Degeneration

(2009) N. Yahata et al.   JOURNAL OF NEUROSCIENCE

Reassessment of Corticospinal Tract Regeneration in Nogo-Deficient Mice

(2009) J. K. Lee et al.   JOURNAL OF NEUROSCIENCE

Nicotinamide Mononucleotide Adenylyl Transferase-Mediated Axonal Protection Requires Enzymatic Activity But Not Increased Levels of Neuronal Nicotinamide Adenine Dinucleotide

(2009) Y. Sasaki et al.   JOURNAL OF NEUROSCIENCE

Nmnat2 delays axon degeneration in superior cervical ganglia dependent on its NAD synthesis activity

(2009) Tingting Yan et al.   NEUROCHEMISTRY INTERNATIONAL

HDAC6 is a target for protection and regeneration following injury in the nervous system

(2009) M. A. Rivieccio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PTP  Is a Receptor for Chondroitin Sulfate Proteoglycan, an Inhibitor of Neural Regeneration

(2009) Y. Shen et al.   SCIENCE

Blockade of hexokinase activity and binding to mitochondria inhibits neurite outgrowth in cultured adult rat sensory neurons

(2008) Zuocheng Wang et al.   NEUROSCIENCE LETTERS

PirB is a Functional Receptor for Myelin Inhibitors of Axonal Regeneration

(2008) J. K. Atwal et al.   SCIENCE

The role of cyclic AMP signaling in promoting axonal regeneration after spinal cord injury

(2007) Sari S. Hannila et al.   EXPERIMENTAL NEUROLOGY