Engineered cellular gene-replacement platform for selective and inducible proteolytic profiling

Regulated Cell Death: Signaling and Mechanisms

(2014) Avi Ashkenazi et al.   Annual Review of Cell and Developmental Biology

Auxin-induced Rapid Degradation of Inhibitor of Caspase-activated DNase (ICAD) Induces Apoptotic DNA Fragmentation, Caspase Activation, and Cell Death

(2014) Kumiko Samejima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isolation of single-base genome-edited human iPS cells without antibiotic selection

(2014) Yuichiro Miyaoka et al.   NATURE METHODS

Proapoptotic Bak and Bax guard against fatal systemic and organ-specific autoimmune disease

(2013) K. D. Mason et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Functional Interplay between Caspase Cleavage and Phosphorylation Sculpts the Apoptotic Proteome

(2012) Melissa M. Dix et al.   CELL

Conservation of caspase substrates across metazoans suggests hierarchical importance of signaling pathways over specific targets and cleavage site motifs in apoptosis

(2012) E D Crawford et al.   CELL DEATH AND DIFFERENTIATION

Complementary Proteomic Tools for the Dissection of Apoptotic Proteolysis Events

(2012) Victoria C. Pham et al.   JOURNAL OF PROTEOME RESEARCH

Global kinetic analysis of proteolysis via quantitative targeted proteomics

(2012) N. J. Agard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of Specific Apoptotic Caspases with an Engineered Small-Molecule-Activated Protease

(2010) Daniel C. Gray et al.   CELL

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Caspases and Kinases in a Death Grip

(2009) Manabu Kurokawa et al.   CELL

Double-strand DNA breaks recruit the centromeric histone CENP-A

(2009) S. G. Zeitlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global Sequencing of Proteolytic Cleavage Sites in Apoptosis by Specific Labeling of Protein N Termini

(2008) Sami Mahrus et al.   CELL

Global Mapping of the Topography and Magnitude of Proteolytic Events in Apoptosis

(2008) Melissa M. Dix et al.   CELL

Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognition

(2008) S Yang et al.   GENE THERAPY

Caspases in apoptosis and beyond

(2008) J Li et al.   ONCOGENE

Apoptosis: controlled demolition at the cellular level

(2007) Rebecca C. Taylor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY