Article
Urology & Nephrology
Reza Sari Motlagh, Mohammad Abufaraj, Lin Yang, Keiichiro Mori, Benjamin Pradere, Ekaterina Laukhtina, Hadi Mostafaei, Victor M. Schuettfort, Fahad Quhal, Francesco Montorsi, Mohsen Amjadi, Christian Gratzke, Shahrokh F. Shariat
Summary: This systematic review and network meta-analysis assessed the efficacy of different penile rehabilitation strategies post radical prostatectomy. The findings suggest that daily or nightly 100 mg sildenafil is the best strategy to improve erectile function recovery, while pelvic floor muscle training also shows effectiveness in increasing erectile function recovery rate.
JOURNAL OF UROLOGY
(2021)
Article
Urology & Nephrology
Francesco Chierigo, Mike Wenzel, Christoph Wuernschimmel, Rocco Simone Flammia, Benedikt Horlemann, Zhe Tian, Fred Saad, Felix K. H. Chun, Markus Graefen, Michele Gallucci, Shahrokh F. Shariat, Guglielmo Mantica, Marco Borghesi, Nazareno Suardi, Carlo Terrone, Pierre Karakiewicz
Summary: This study compared the survival rates between hormone therapy and hormone therapy plus chemotherapy in high-risk patients. The results showed that hormone therapy had a better cancer-specific survival rate in the overall NCCN high-risk cohort and the JH high-risk and very high-risk subgroup.
JOURNAL OF UROLOGY
(2022)
Article
Andrology
Jongsoo Lee, Hye Rim Kim, Ji Eun Heo, Won Sik Jang, Kwang Suk Lee, Sung Ku Kang, Hyunho Han, Young Deuk Choi
Summary: This study investigated the impact of phosphodiesterase-5 inhibitor (PDE5i) use on survival outcomes after robot-assisted radical prostatectomy (RARP). The results showed that PDE5i use was associated with improved overall survival and reduced risk of death.
WORLD JOURNAL OF MENS HEALTH
(2022)
Article
Urology & Nephrology
Praful Ravi, Lucia Kwak, Wanling Xie, Kaitlin Kelleher, Andres M. Acosta, Rana R. McKay, Adam S. Kibel, Mary-Ellen Taplin
Summary: This study compared the outcomes of neoadjuvant therapy with a novel hormonal agent (NHA) prior to radical prostatectomy (RP) and up-front RP in patients with high-risk prostate cancer (HRPC). After adjusting for potential confounding factors, the neoadjuvant RP group showed longer time to biochemical recurrence (BCR) and superior metastasis-free survival (MFS) compared to the up-front RP group. The rates of adjuvant and salvage therapy were also lower in the neoadjuvant RP cohort.
JOURNAL OF UROLOGY
(2022)
Article
Andrology
Yosuke Mitsui, Takuya Sadahira, Yuki Maruyama, Ryota Sato, Acosta Gonzalez Herik Rodrigo, Koichiro Wada, Motoo Araki, Masami Watanabe, Toyohiko Watanabe, Yasutomo Nasu
Summary: Sarcopenia may have a negative impact on erectile functional outcomes after nerve-sparing robot-assisted radical prostatectomy (RARP). Sarcopenia and a lower preoperative IIEF-5 score may predict postoperative erectile dysfunction.
WORLD JOURNAL OF MENS HEALTH
(2021)
Article
Urology & Nephrology
Mohammed Shahait, Ryan W. Dobbs, Jessica L. Kim, Nancy Eldred, Karren Liang, Linda M. Huynh, Thomas E. Ahlering, Vipul Patel, David I. Lee
Summary: The study suggests that robot-assisted radical prostatectomy is a feasible treatment option for octogenarian men with localized prostate cancer, showing favorable perioperative outcomes and functional recovery. Careful patient selection and counseling are essential in ensuring successful surgical outcomes for this age group.
JOURNAL OF ENDOUROLOGY
(2021)
Article
Urology & Nephrology
Maggie C. Lee, Tyler R. Erickson, Shannon Stock, Lauren E. Howard, Amanda M. De Hoedt, Christopher L. Amling, William J. Aronson, Matthew R. Cooperberg, Christopher J. Kane, Martha K. Terris, Zachary Klaassen, Stephen J. Freedland, Christopher J. D. Wallis
Summary: The study found that among men with intermediate/high-risk prostate cancer, delayed treatment up to 1 year following diagnosis did not significantly increase the risk of adverse long-term outcomes, including castration-resistant prostate cancer, metastasis, and death.
JOURNAL OF UROLOGY
(2022)
Article
Urology & Nephrology
Cameron J. Britton, Vidit Sharma, Anthony E. Fadel, Elizabeth Bearrick, Bridget L. Findlay, Igor Frank, Matthew K. Tollefson, R. Jeffrey Karnes, Boyd R. Viers
Summary: The study aims to identify risk factors for vesicourethral anastomotic stenosis after radical prostatectomy and further characterize its natural progression and treatment patterns. It was found that surgical technique, perioperative morbidity, and patient-related factors influence the risk of vesicourethral anastomotic stenosis, which is independently associated with increased risk of urinary incontinence.
JOURNAL OF UROLOGY
(2023)
Article
Urology & Nephrology
Mohammed Shahait, Joseph G. Cheaib, Elai Davicioni, Yang Liu, Ibrahim Abu Ghaida, Ryan W. Dobbs, Mohamed Alshalalfa, Priti Lal, Daniel J. Lee, David I. Lee
Summary: This study examined the correlation between perioperative testosterone levels and genomic risk scores in men undergoing radical prostatectomy. It found that there was no clinical correlation between pre-defined genomic risk score groups and testosterone groups, suggesting a limited role of endogenous testosterone in the development of de novo high-risk localized prostate cancer.
JOURNAL OF UROLOGY
(2022)
Article
Urology & Nephrology
Sagnjun Yoo, Bumjin Lim, Se Young Choi, Dalsan You, Choung-Soo Kim
Summary: This study investigated the relationship between the width of spared neurovascular bundle (NVB) during robot-assisted laparoscopic prostatectomy and postoperative sexual outcomes. The width of spared NVB was found to be a significant predictor for postoperative 6-month erectile hardness score >= 2. Measurement of the width of NVB during surgery could be an easy intraoperative method for assessing the quality of NVB sparing.
PROSTATE INTERNATIONAL
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mi Yeon Park, Kye Jin Park, Mi-hyun Kim, Jeong Kon Kim
Summary: A simplified MRI-based model was developed to predict the risk of positive surgical margins after radical prostatectomy in patients with prostate cancer. The model showed good prediction performance and calibration using tumor characteristics on MRI images. This scoring system can help estimate the risk of positive surgical margins after radical prostatectomy.
EUROPEAN RADIOLOGY
(2021)
Article
Urology & Nephrology
Justin D. Oake, Benjamin Shiff, Oksana Harasemiw, Navdeep Tangri, Thomas W. Ferguson, Bimal Bhindi, Jeff W. Saranchuk, Rahul K. Bansal, Darrel E. Drachenberg, Jasmir G. Nayak
Summary: The study compared outcomes of patients with nonmetastatic prostate cancer treated with radical prostatectomy or radiation therapy. It found that radical prostatectomy was associated with higher overall survival and lower prostate cancer specific mortality compared to radiation therapy.
JOURNAL OF UROLOGY
(2022)
Article
Urology & Nephrology
Rafael Castilho Borges, Rafael Rocha Tourinho-Barbosa, Sidney Glina, Petr Macek, Annick Mombet, Rafael Sanchez-Salas, Xavier Cathelineau
Summary: The study aimed to compare the impact of focal and whole gland ablation on erectile function and urinary continence for prostate cancer patients. Results showed that focal therapy is the key factor in improving sexual function and urinary continence recovery.
JOURNAL OF UROLOGY
(2021)
Article
Urology & Nephrology
Justin D. Oake, Benjamin Shiff, Oksana Harasemiw, Navdeep Tangri, Thomas W. Ferguson, Bimal Bhindi, Jeff W. Saranchuk, Rahul K. Bansal, Darrel E. Drachenberg, Jasmir G. Nayak
Summary: This study compared the outcomes of radiation therapy (RT) and radical prostatectomy (RP) for nonmetastatic prostate cancer patients. The findings showed that RT was associated with higher all-cause mortality and prostate cancer specific mortality rates compared to RP.
JOURNAL OF UROLOGY
(2022)
Article
Urology & Nephrology
Antonio Galfano, Stefano Tappero, Christopher Eden, Paolo Dell'oglio, Karen Fransis, Hongqian Guo, Keith Kowalczyk, Mattia Longoni, Rabii Madi, Koon H. Rha, Silvia Secco, Xuefeng Qiu, Rashid Sayyid, Aldo M. Bocciardi
Summary: This study retrospectively evaluated the results of Retzius-Sparing robot-assisted radical Prostatectomy (RSP) in high-risk prostate cancer (HR-PCa) patients, performed by expert surgeons in a multicentric setting. The study found that RSP achieved good urinary continence recovery and could predict the occurrence of positive surgical margins (PSMs) to some extent.
MINERVA UROLOGY AND NEPHROLOGY
(2022)