Single-molecule view of basal activity and activation mechanisms of the G protein-coupled receptor β2AR

Structural Insights into the Dynamic Process of β 2 -Adrenergic Receptor Signaling

(2015) Aashish Manglik et al.   CELL

Demystifying PIFE: The Photophysics Behind the Protein-Induced Fluorescence Enhancement Phenomenon in Cy3

(2015) Elana M. S. Stennett et al.   Journal of Physical Chemistry Letters

Conformational dynamics of a class C G-protein-coupled receptor

(2015) Reza Vafabakhsh et al.   NATURE

Fine tuning of sub-millisecond conformational dynamics controls metabotropic glutamate receptors agonist efficacy

(2014) Linnea Olofsson et al.   Nature Communications

β2-Adrenergic Receptor Activation by Agonists Studied with19F NMR Spectroscopy

(2013) Reto Horst et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Dynamic Process of β2-Adrenergic Receptor Activation

(2013) Rie Nygaard et al.   CELL

Protein induced fluorescence enhancement (PIFE) for probing protein–nucleic acid interactions

(2013) Helen Hwang et al.   CHEMICAL SOCIETY REVIEWS

Dynamics of Site Switching in DNA Polymerase

(2013) Rajan Lamichhane et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Role of Ligands on the Equilibria Between Functional States of a G Protein-Coupled Receptor

(2013) Tae Hun Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single-Molecule Förster Resonance Energy Transfer Reveals an Innate Fidelity Checkpoint in DNA Polymerase I

(2012) Svitlana Y. Berezhna et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biased Signaling Pathways in  2-Adrenergic Receptor Characterized by 19F-NMR

(2012) J. J. Liu et al.   SCIENCE

Efficacy of the β2-adrenergic receptor is determined by conformational equilibrium in the transmembrane region

(2012) Yutaka Kofuku et al.   Nature Communications

Conformational Dynamics of Single G Protein-Coupled Receptors in Solution

(2011) Samuel Bockenhauer et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

Activation mechanism of the  2-adrenergic receptor

(2011) R. O. Dror et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein induced fluorescence enhancement as a single molecule assay with short distance sensitivity

(2011) H. Hwang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The selectivity of β-adrenoceptor agonists at human β1-, β2- and β3-adrenoceptors

(2010) Jillian G Baker   BRITISH JOURNAL OF PHARMACOLOGY

Differential Signaling of the Endogenous Agonists at the β2-Adrenergic Receptor

(2010) Susanne Reiner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single-molecule FRET of protein–nucleic acid and protein–protein complexes: Surface passivation and immobilization

(2010) Rajan Lamichhane et al.   METHODS

Membrane protein assembly into Nanodiscs

(2009) Timothy H. Bayburt et al.   FEBS LETTERS

The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex

(2009) X. J. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stabilization of the Human β2-Adrenergic Receptor TM4–TM3–TM5 Helix Interface by Mutagenesis of Glu1223.41, A Critical Residue in GPCR Structure

(2007) Christopher B. Roth et al.   JOURNAL OF MOLECULAR BIOLOGY