Review
Clinical Neurology
Yanjuan Song, Tong Li, Chunlian Ma, Hui Liu, Fengxia Liang, Yi Yang
Summary: This study conducted a network meta-analysis to compare the effects of acupuncture-related therapy for migraine. The results suggest that acupuncture-related therapy, especially conventional acupuncture, can effectively improve migraine symptoms. However, more high-quality studies are needed to confirm these findings.
FRONTIERS IN NEUROLOGY
(2022)
Review
Multidisciplinary Sciences
Pingping Su, Xiuzhen Xie, Yingqi Xu, Xinxin Luo, Jianli Niu, Zhuqing Jin
Summary: This study systematically evaluated the effectiveness and potential mechanisms of acupuncture in treating an experimental migraine model in rats. The findings showed that acupuncture significantly reduced behavioral scores in rats with migraine and downregulated the expression of CGRP, SP, and NO in serum, as well as stimulated Gsa in the brainstem. Acupuncture also increased the content of Gia in the brainstem and 50%PWT. In conclusion, acupuncture effectively improves the behavioral performance in rats with migraine, potentially through its inhibition of meningeal vasodilation, inflammatory factors, and neurogenic inflammation.
Article
Clinical Neurology
Hui Zheng, Tao Gao, Qian-Hua Zheng, Ling-Yun Lu, Ting-Hui Hou, Shu-Sen Zhang, Si-Yuan Zhou, Xin-Yu Hao, Lu Wang, Ling Zhao, Fan-Rong Liang, Ying Li
Summary: This study aimed to investigate the effectiveness of acupuncture for chronic tension-type headache (CTTH) through a randomized controlled trial. The results showed that the responder rate at both 16 weeks and 32 weeks of follow-up was significantly higher in the true acupuncture (TA) group compared to the superficial acupuncture (SA) group. Additionally, the reduction in the number of headache days was greater in the TA group. Only a few mild adverse events were reported in the TA group.
Review
Neurosciences
Ma Peihong, Qu Yuzhu, Yin Tao, He Zhaoxuan, Cheng Shirui, Teng Yuke, Xie Kunnan, Li Shenghong, Sun Ruirui, Zeng Fang
Summary: With the advancement of neuroimaging techniques, the central mechanism of acupuncture analgesia has gained increasing attention. Analysis of 27 studies revealed that heat stimulation and electroacupuncture were commonly used pain modeling methods, with the anterior cingulate cortex and insula being frequently reported brain regions associated with acupuncture analgesia.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Adriana Della Pietra, Rashid Giniatullin, Juha R. Savinainen
Summary: This study suggests using the endogenous cannabinoid system to alleviate migraine pain by inhibiting enzymes degrading endocannabinoids for analgesic effects. The activity of MAGL was significantly higher than FAAH in trigeminal ganglia, suggesting it as a priority target for blocking peripheral mechanisms of migraine pain. In the central nervous system, both MAGL and FAAH could serve as potential targets for reducing migraine-related enhanced cortical excitability and pain transmission.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Clinical Neurology
Gianni Allais, Giulia Chiarle, Emma Sinatra, Gisella Airola, Fabiola Bergandi, Sara Rolando, Silvia Sinigaglia, Paola Schiapparelli, Chiara Benedetto
Summary: Preliminary data from this study suggest that acupuncture may be safe for pregnant women with migraines, with no significant side effects observed. Although there is limited data on acupuncture for migraines during pregnancy, there is ample evidence supporting the efficacy and safety of acupuncture for migraines in the general population.
NEUROLOGICAL SCIENCES
(2022)
Review
Cell Biology
Yingchen Li, Yi Yu, Yuhang Liu, Wei Yao
Summary: This review provides a scientific explanation of acupuncture analgesia, focusing on the relationship between mast cells and acupoints. It discusses how acupuncture can stimulate mast cells to release bioactive substances and activate nerve receptors to generate analgesic effects. It also highlights the importance of local mast cell density in the acupuncture effect.
Review
Oncology
Jaung-Geng Lin, Peddanna Kotha, Yi-Hung Chen
Summary: Acupuncture involves stimulating specific acupoints on the body to relieve pain. It has been proven effective for acute and chronic pain relief. The mechanisms of acupuncture involve modulation of neurotransmissions and the release of specific substances in the body.
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2022)
Review
Clinical Neurology
Shi-Qi Fan, Song Jin, Tai-Chun Tang, Min Chen, Hui Zheng
Summary: The study found that acupuncture is more effective in preventing migraines compared to sham acupuncture, and it is also a safer alternative to conventional drug therapy. In terms of responder rate, acupuncture was statistically significantly superior to sham acupuncture and conventional drugs. Acupuncture also resulted in fewer adverse events compared to prophylactic medication.
JOURNAL OF NEUROLOGY
(2021)
Article
Medicine, General & Internal
Taras Usichenko, Berthold Johannes Henkel, Catharina Klausenitz, Thomas Hesse, Guillermo Pierdant, Mike Cummings, Klaus Hahnenkamp
Summary: This study evaluated the efficacy and effectiveness of acupuncture as an adjunctive therapy for pain control after cesarean delivery. The results showed that acupuncture was safe and effective in reducing pain and accelerating the recovery of patients after cesarean delivery.
Article
Cell Biology
Li-Na Wang, Xue-Zhi Wang, Yu-Jia Li, Bing-Rong Li, Meng Huang, Xiao-Yu Wang, Ryszard Grygorczyk, Guang-Hong Ding, Wolfgang Schwarz
Summary: This review provides experimental evidence that subcutaneous mast cells play a role in the analgesic effects of acupuncture. The manipulation of acupuncture needles activates mast cells, leading to the release of various mediators that reduce the electrical activities of sensory neurons, resulting in analgesia. This finding is of great significance in further understanding the mechanisms of acupuncture.
Article
Rheumatology
Jian-Feng Tu, Jing-Wen Yang, Guang-Xia Shi, Zhang-Sheng Yu, Jin-Ling Li, Lu-Lu Lin, Yu-Zheng Du, Xiao-Gang Yu, Hui Hu, Zhi-Shun Liu, Chun-Sheng Jia, Li-Qiong Wang, Jing-Jie Zhao, Jun Wang, Tong Wang, Yang Wang, Tian-Qi Wang, Na Zhang, Xuan Zou, Yu Wang, Jia-Kai Shao, Cun-Zhi Liu
Summary: The study found that intensive EA can reduce pain and improve function in patients with knee OA, with long-lasting effects. Intensive MA, on the other hand, showed no benefit for knee OA at week 8, but exhibited some benefits during follow-up.
ARTHRITIS & RHEUMATOLOGY
(2021)
Review
Medicine, General & Internal
Qifu Li, Jialei Feng, Xinghe Zhang, Yanan Wang, Siwen Zhao, Chonghui Xing, Yongli Song, Xuanxiang Zeng, Meng Kong, Yunqiu Zheng, Ling Zhao, Taipin Guo
Summary: This is a clinical trial in China that aims to evaluate the efficacy of contralateral acupuncture (CAT) in women with unilateral migraine without aura (MwoA). The study will compare CAT with ipsilateral acupuncture (IAT) and sham acupuncture. The primary outcome is the changes in days of migraine attacks, and secondary outcomes include frequency, intensity, duration of migraines, medication intake, quality of life, disability assessment, headache impact, and sleep quality. The data will be collected at baseline, end of treatment, and follow-up visits. The study has received ethics approval and the results will be published and presented at conferences.
Article
Oncology
Chong Li, Xinyi Li, Ke He, Yang Wu, Xiaoming Xie, Jiju Yang, Fan Zhang, Yang Yue, Huifeng Hao, Shaokun Zhao, Xin Li, Guihua Tian
Summary: This study investigated the effect of acupuncture on migraine patients and found that acupuncture effectively relieved migraine symptoms in a way different from sham acupuncture. The anti-migraine mechanism of acupuncture involves a complex network related to the regulation of the response to hypoxic stress, reversal of brain energy imbalance, and regulation of inflammation. Acupuncture affected brain regions including the lingual gyrus, default mode network, and cerebellum.
FRONTIERS OF MEDICINE
(2023)
Article
Neurosciences
Lu Liu, Claire-Shuiqing Zhang, Hui-Lin Liu, Fan He, Tian-Li Lyu, Lin Zeng, Luo-Peng Zhao, Mi-Na Wang, Zheng-Yang Qu, Li-Min Nie, Jia Guo, Xiao-Zhe Zhang, Yong-Hui Lu, Ke-Lun Wang, Bin Li, Xiang-Hong Jing, Lin-Peng Wang
Summary: This study indicates that acupuncture can reduce the number of migraine days experienced by patients with menstruation-related migraine compared to medication. The preventive effect of acupuncture treatment can be sustained for six cycles for patients who received the treatment over three cycles.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Oncology
Denise Shuk Ting Cheung, Wing Fai Yeung, Pui Hing Chau, Tai Chung Lam, Mingxiao Yang, Kithelia Lai, Chun Yat Ip, Lixing Lao, Chia-Chin Lin
Summary: The study suggests that patient-centred self-administered acupressure is feasible and acceptable among advanced cancer patients receiving treatment. Although there were improvements in some outcomes, only the difference in anxiety post-intervention was significant.
EUROPEAN JOURNAL OF CANCER CARE
(2022)
Meeting Abstract
Oncology
Rui Wang, Mingxiao Yang, Iris Zhi, Ting Bao
Article
Engineering, Electrical & Electronic
Yuchen Tang, Robert C. Roberts, Cheuk Him Michael Lam, Wai Shan Wong, Mingxiao Yang, Lixing Lao, Wei-Ning Lee
Summary: Wrist-site pulse-sensing devices have gained attention for monitoring human body conditions, but their accuracy has not been validated against medical imaging. This study proposed the use of high-frequency and high frame-rate ultrasound imaging to substantiate human pulse-taking. A prototype device was developed and validated in vitro and in vivo. The results showed a high correlation between the pulse waveforms detected by the prototype and those obtained from ultrasound imaging.
IEEE SENSORS JOURNAL
(2022)
Article
Pharmacology & Pharmacy
Mingxiao Yang, Raymond E. Baser, Susan Q. Li, Yen-Nien Hou, Kamyar Chong, Yi Lily Zhang, Irfan Hoque, Ting Bao, Jun J. Mao
Summary: This article describes a clinical trial on the use of Tibetan herbal pain-relieving plaster for chronic musculoskeletal pain in cancer survivors. The trial will assess the safety and efficacy of the plaster and monitor adverse events during the treatment period. With rigorous design and implementation, the trial aims to provide initial evidence on the effectiveness and safety of the pain-relieving plaster for cancer survivors with chronic musculoskeletal pain.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Pan Zhang, Yalan Chen, Furong Zhang, Hong Pei, Mingsheng Sun, Yuzhu Qu, Jiyao Chen, Ting Du, Xiaoguo He, Fanrong Liang, Weiguo Jia, Mingxiao Yang
Summary: This study aims to evaluate the antihypertensive effect of acupuncture and determine the associated metabolic improvements among patients with essential hypertension. It is a randomized clinical trial that will collect biospecimens for metabolic profiling. The study results will provide important clinical data regarding the efficacy of acupuncture for essential hypertension and offer insights into its effect on metabolism.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Engineering, Biomedical
Qingyun Huang, Cong Wu, Senlin Hou, Kuanming Yao, Hui Sun, Yufan Wang, Yikai Chen, Junhui Law, Mingxiao Yang, Ho-yin Chan, Vellaisamy A. L. Roy, Yuliang Zhao, Dong Wang, Enming Song, Xinge Yu, Lixing Lao, Yu Sun, Wen Jung Li
Summary: This article introduces a 3D graphene-based ear-conformable sensing device with embedded and distributed 3D electrodes for full-auricle physiological monitoring. By studying more than 30 ears, specific AESR changes in the auricular region after cycling exercise were observed and clustered into four groups through machine learning-based data analysis. Furthermore, correlations between AESR and heart rate and blood pressure were studied.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Oncology
Mingxiao Yang, Raymond E. Baser, Kevin T. Liou, Susan Q. Li, Lauren Piulson, Katherine S. Panageas, Jun J. Mao
Summary: This study analyzed the sleep quality data from a randomized clinical trial and found that acupuncture provided greater improvements in sleep quality for cancer survivors with pain compared to usual care. The improvement in sleep quality was sustained after the treatment ended.
Article
Clinical Neurology
Mingxiao Yang, Raymond E. Baser, Raya Khanin, Isidora Autuori, Qing S. Li, Katherine S. Panageas, Irene Orlow, Jun J. Mao
Summary: The COMT Val158Met genetic polymorphism influences the analgesic response to electroacupuncture, but has less impact on the response to auricular acupuncture and usual care. This finding provides new insights into personalized nonpharmacologic pain management tailored to individual genetic backgrounds.
Article
Materials Science, Multidisciplinary
ManFu Wang, JinGang Zhang, WeiJia Tang, MingXiao Yang, SiFan Wang, GuiBing Pang, ZhiHua Zhang, Zhong Lan
Summary: In this study, the high-precision surface of 201 stainless steel was investigated using electrochemical micro-machining with and without magnetic field-assisted. The results showed that the surface roughness of the samples was reduced to 0.40μm after 18 min of electrochemical micro-machining, and further improved to 0.20μm with the introduction of the magnetic field. The magnetic field-assisted electrochemical micro-machining provided lower surface roughness, indicating the favorable impact of the magnetic field on machining efficiency. The simulation results demonstrated that the existence of the magnetic field enhanced the current density on the anode surface and the mass transfer rate of the electrolyte, leading to accelerated electrochemical reaction behavior and improved processing efficiency.
JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE
(2023)
Review
Integrative & Complementary Medicine
Xiaotong Li, Mingxiao Yang, Yi Lily Zhang, Yen-Nien Hou, Colleen M. Smith, Deborah Korenstein, Jun J. Mao
Summary: This study aimed to assess the efficacy and safety of ginseng and ginseng herbal formulas for fatigue in randomized clinical trials. The findings showed that ginseng herbal formulas significantly improved fatigue severity, especially among patients with chronic fatigue, although the effect size was small. Rigorous trials and standardized guidelines for ginseng usage are needed for further evaluation.
JOURNAL OF INTEGRATIVE AND COMPLEMENTARY MEDICINE
(2023)
Review
Oncology
Mingxiao Yang, Hui Wang, Yi Lily Zhang, Furong Zhang, Xiaotong Li, Soo-Dam Kim, Yalan Chen, Jiyao Chen, Susan Chimonas, Deborah Korenstein, Jun J. Mao
Summary: This study systematically searched randomized trials of Suanzaoren for improving sleep outcomes and found that Suanzaoren was associated with significant improvements in subjective sleep quality in insomnia and sleep disturbance patients compared to placebo. However, due to small sample size and variable study quality, the clinical benefits and harms of Suanzaoren, particularly in the long term, should be further assessed.
INTEGRATIVE CANCER THERAPIES
(2023)
Review
Health Care Sciences & Services
Mingxiao Yang, Ting Du, Hulin Long, Mingsheng Sun, Fanrong Liang, Lixing Lao
Summary: This study aimed to evaluate the efficacy of acupuncture on menstrual migraine. The results showed that acupuncture did not significantly reduce the frequency and pain intensity of menstrual migraine. Although there was some improvement in headache intensity compared to drugs, all studies had small sample sizes and risk of bias.
BMJ SUPPORTIVE & PALLIATIVE CARE
(2022)
Review
Oncology
Hui Wang, Yen-Nien Hou, Mingxiao Yang, Ye Feng, Yi Lily Zhang, Colleen M. Smith, Wei Hou, Jun J. Mao, Gary Deng
Summary: This study evaluated the efficacy and safety of Shenling Baizhu San (SBS), a Chinese herbal formula, in treating chronic diarrhea. The results showed that SBS, either combined with or without conventional medicine, significantly improved patient-reported satisfaction and had no increased risk of adverse events. However, more rigorous and powered research is needed to confirm the effects of SBS in specific populations with chronic diarrhea symptoms.
INTEGRATIVE CANCER THERAPIES
(2022)
Review
Biochemistry & Molecular Biology
Soo-Dam Kim, Eun-Bin Kwag, Ming-Xiao Yang, Hwa-Seung Yoo
Summary: The study investigated the effectiveness and safety of using ginger to treat CINV in breast cancer patients. The results showed that ginger can reduce the occurrence of CINV and is effective in managing both acute and delayed CINV.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Integrative & Complementary Medicine
Chen Haiyong, Yeung Wing-Fai, Yang Mingxiao, Mu Jinglan, Ziea Tat-Chi, Ng Bacon Fung-Leung, Lao Lixing
Summary: The study aims to develop a clinical practice guideline for the treatment of low back pain using acupuncture. An integrative approach, including systematic review of literature, clinical evidence classification, expert opinion surveying, and consensus establishing, was utilized. The guideline takes into consideration evidence-based practice standards and personalized features of acupuncture, providing recommendations for diagnosis, treatment, rehabilitation, and follow-ups.
JOURNAL OF TRADITIONAL CHINESE MEDICINE
(2022)