Prediction of brain clozapine and norclozapine concentrations in humans from a scaled pharmacokinetic model for rat brain and plasma pharmacokinetics

Published 2014 View Full Article

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Title
Prediction of brain clozapine and norclozapine concentrations in humans from a scaled pharmacokinetic model for rat brain and plasma pharmacokinetics
Authors
Keywords
Clozapine, Norclozapine, Receptor occupancy, Population pharmacokinetics, Translational modeling, NONMEM
Journal
Journal of Translational Medicine
Volume 12, Issue 1, Pages 203
Publisher
Springer Nature
Online
2014-08-20
DOI
10.1186/1479-5876-12-203

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