Cardiac protective effects of irbesartan via the PPAR-gamma signaling pathway in angiotensin-converting enzyme 2-deficient mice

Losartan protects liver against ischaemia/reperfusion injury through PPAR-γ activation and receptor for advanced glycation end-products down-regulation

(2013) Eun-Ji Koh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Multiple Functions of Angiotensin-Converting Enzyme 2 and Its Relevance in Cardiovascular Diseases

(2013) Keiji Kuba et al.   CIRCULATION JOURNAL

Peroxisome Proliferator–Activated Receptor-γ Activation Prevents Sepsis-Related Cardiac Dysfunction and Mortality In Mice

(2013) Konstantinos Drosatos et al.   Circulation-Heart Failure

A Lectin-EGF antibody promotes regulatory T cells and attenuates nephrotoxic nephritis via DC-SIGN on dendritic cells

(2013) Minchao Cai et al.   Journal of Translational Medicine

Cardiac and Renal Protective Effects of Irbesartan via Peroxisome Proliferator‐Activated Receptorγ–Hepatocyte Growth Factor Pathway Independent of Angiotensin II Type 1a Receptor Blockade in Mouse Model of Salt‐Sensitive Hypertension

(2013) Hiroshi Kusunoki et al.   Journal of the American Heart Association

Cardioprotective Effects Mediated by Angiotensin II Type 1 Receptor Blockade and Enhancing Angiotensin 1-7 in Experimental Heart Failure in Angiotensin-Converting Enzyme 2–Null Mice

(2012) Vaibhav B. Patel et al.   HYPERTENSION

Possible Involvement of Angiotensin-Converting Enzyme 2 and Mas Activation in Inhibitory Effects of Angiotensin II Type 1 Receptor Blockade on Vascular Remodeling

(2012) Masaru Iwai et al.   HYPERTENSION

Proteome changes in the myocardium of experimental chronic diabetes and hypertension

(2012) S. Ares-Carrasco et al.   Journal of Proteomics

Altered serum levels of IL-33 in patients with advanced systolic chronic heart failure: correlation with oxidative stress

(2012) Hai-Feng Zhang et al.   Journal of Translational Medicine

ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation

(2012) Tatsuo Hashimoto et al.   NATURE

ACE2 Deficiency Enhances Angiotensin II-Mediated Aortic Profilin-1 Expression, Inflammation and Peroxynitrite Production

(2012) Hai-Yan Jin et al.   PLoS One

Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47phox NADPH oxidase subunit

(2011) Sreedhar Bodiga et al.   CARDIOVASCULAR RESEARCH

Mice With Cardiac Overexpression of Peroxisome Proliferator–Activated Receptor γ Have Impaired Repolarization and Spontaneous Fatal Ventricular Arrhythmias

(2011) John P. Morrow et al.   CIRCULATION

Elevated Expression of Connective Tissue Growth Factor in Human Atrial Fibrillation and Angiotensin II-Treated Cardiomyocytes

(2011) Wen-Chin Ko et al.   CIRCULATION JOURNAL

Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction

(2010) JiuChang Zhong et al.   CIRCULATION

Potential Therapeutic Targets for Cardiac Fibrosis

(2010) Andrew Leask   CIRCULATION RESEARCH

Mitogen-Activated Protein Kinase–Activated Protein Kinase 2 in Angiotensin II–Induced Inflammation and Hypertension

(2010) Talin Ebrahimian et al.   HYPERTENSION

Prevention of Angiotensin II–Mediated Renal Oxidative Stress, Inflammation, and Fibrosis by Angiotensin-Converting Enzyme 2

(2010) JiuChang Zhong et al.   HYPERTENSION

Involvement of NADPH oxidase in age-associated cardiac remodeling

(2010) Mingyi Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Telmisartan attenuates aortic hypertrophy in hypertensive rats by the modulation of ACE2 and profilin-1 expression

(2010) Jiu-Chang Zhong et al.   REGULATORY PEPTIDES

Loss of Angiotensin-Converting Enzyme 2 Accelerates Maladaptive Left Ventricular Remodeling in Response to Myocardial Infarction

(2009) Zamaneh Kassiri et al.   Circulation-Heart Failure

Defective peroxisomal proliferators activated receptor gamma activity due to dominant-negative mutation synergizes with hypertension to accelerate cardiac fibrosis in mice

(2009) Adrienn Kis et al.   EUROPEAN JOURNAL OF HEART FAILURE

Signal transduction involved in CTGF-induced production of chemokines in mesangial cells

(2008) Sheng-Hua Wu et al.   GROWTH FACTORS

Enhanced angiotensin converting enzyme 2 regulates the insulin/Akt signalling pathway by blockade of macrophage migration inhibitory factor expression

(2007) J-C Zhong et al.   BRITISH JOURNAL OF PHARMACOLOGY