Nimotuzumab promotes radiosensitivity of EGFR-overexpression esophageal squamous cell carcinoma cells by upregulating IGFBP-3

Decreased expression of zinc-alpha2-glycoprotein in hepatocellular carcinoma associates with poor prognosis

(2012) Yan Huang et al.   Journal of Translational Medicine

The overexpression of IGFBP-3 is involved in the chemosensitivity of esophageal squamous cell carcinoma cells to nimotuzumab combined with cisplatin

(2012) Lei Zhao et al.   TUMOR BIOLOGY

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Bivalent binding by intermediate affinity of nimotuzumab: A contribution to explain antibody clinical profile

(2011) Greta Garrido et al.   CANCER BIOLOGY & THERAPY

IGFBP3 and BAG1 enhance radiation-induced apoptosis in squamous esophageal cancer cells

(2010) Kei Yoshino et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Chk1 inhibitor Gö6976 enhances the sensitivity of nasopharyngeal carcinoma cells to radiotherapy and chemotherapy in vitro and in vivo

(2010) Zizhen Feng et al.   CANCER LETTERS

Insulin-like growth factor-binding protein-3 promotes transforming growth factor-β1-mediated epithelial-to-mesenchymal transition and motility in transformed human esophageal cells

(2010) Mitsuteru Natsuizaka et al.   CARCINOGENESIS

Radiosensitisation of U87MG brain tumours by anti-epidermal growth factor receptor monoclonal antibodies

(2009) A Diaz Miqueli et al.   BRITISH JOURNAL OF CANCER

Nimotuzumab, an Antitumor Antibody that Targets the Epidermal Growth Factor Receptor, Blocks Ligand Binding while Permitting the Active Receptor Conformation

(2009) A. Talavera et al.   CANCER RESEARCH

Epidermal growth factor receptor in relation to tumor development: EGFR-targeted anticancer therapy

(2009) Isamu Okamoto   FEBS Journal

Enhancement of the antitumor activity of ionising radiation by nimotuzumab, a humanised monoclonal antibody to the epidermal growth factor receptor, in non-small cell lung cancer cell lines of differing epidermal growth factor receptor status

(2008) Y Akashi et al.   BRITISH JOURNAL OF CANCER

ApoG2, a novel inhibitor of antiapoptotic Bcl-2 family proteins, induces apoptosis and suppresses tumor growth in nasopharyngeal carcinoma xenografts

(2008) Zhe-Yu Hu et al.   INTERNATIONAL JOURNAL OF CANCER

Phase III Trial of Trimodality Therapy With Cisplatin, Fluorouracil, Radiotherapy, and Surgery Compared With Surgery Alone for Esophageal Cancer: CALGB 9781

(2008) Joel Tepper et al.   JOURNAL OF CLINICAL ONCOLOGY

Structural Basis for EGF Receptor Inhibition by the Therapeutic Antibody IMC-11F8

(2008) Shiqing Li et al.   STRUCTURE