In-depth physiological characterization of primary human hepatocytes in a 3D hollow-fiber bioreactor

Lidocaine/Monoethylglycinexylidide Test, Galactose Elimination Test, and Sorbitol Elimination Test for Metabolic Assessment of Liver Cell Bioreactors

(2010) Jörg C. Gerlach et al.   ARTIFICIAL ORGANS

HepaRG human hepatic cell line utility as a surrogate for primary human hepatocytes in drug metabolism assessment in vitro

(2010) Marc Lübberstedt et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Effect of human patient plasma ex vivo treatment on gene expression and progenitor cell activation of primary human liver cells in multi-compartment 3D perfusion bioreactors for extra-corporeal liver support

(2009) Eva Schmelzer et al.   BIOTECHNOLOGY AND BIOENGINEERING

Serum-free collagen sandwich cultures of adult rat hepatocytes maintain liver-like properties long term: A valuable model for in vitro toxicity and drug–drug interaction studies

(2009) Gregor Tuschl et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Nitric Oxide and Redox Regulation in the Liver: Part I. General Considerations and Redox Biology in Hepatitis

(2009) Diana L. Diesen et al.   JOURNAL OF SURGICAL RESEARCH

Perfused multiwell plate for 3D liver tissue engineering

(2009) Karel Domansky et al.   LAB ON A CHIP

Oxygen-mediated enhancement of primary hepatocyte metabolism, functional polarization, gene expression, and drug clearance

(2009) S. Kidambi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic 3D Culture Promotes Spontaneous Embryonic Stem Cell Differentiation In Vitro

(2009) Jörg C. Gerlach et al.   TISSUE ENGINEERING PART C-METHODS

Effects of drugs in subtoxic concentrations on the metabolic fluxes in human hepatoma cell line Hep G2

(2009) Jens Niklas et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

An integrated approach to improved toxicity prediction for the safety assessment during preclinical drug development using Hep G2 cells

(2009) Fozia Noor et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

High throughput, non-invasive and dynamic toxicity screening on adherent cells using respiratory measurements

(2009) Simone Beckers et al.   TOXICOLOGY IN VITRO

Species-specific toxicity of diclofenac and troglitazone in primary human and rat hepatocytes

(2008) Birthe Lauer et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Drug-induced liver injury through mitochondrial dysfunction: mechanisms and detection during preclinical safety studies

(2008) Gilles Labbe et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Differentiation of mouse and human embryonic stem cells into hepatic lineages

(2008) Nobuaki Shiraki et al.   GENES TO CELLS

Species-specific differences in coumarin-induced hepatotoxicity as an example toxicogenomics-based approach to assessing risk of toxicity to humans

(2008) T Uehara et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Isolation and Characterization of Adult Human Liver Progenitors from Ischemic Liver Tissue Derived from Therapeutic Hepatectomies

(2008) Harald Stachelscheid et al.   TISSUE ENGINEERING PART A

Arginase release by primary hepatocytes and liver slices results in rapid conversion of arginine to urea in cell culture media

(2008) Stephan J.A.C. Peters et al.   TOXICOLOGY IN VITRO

Construction and Performance of a Minibioreactor Suitable as Experimental Bioartificial Liver

(2007) Joaquín V. Rodriguez et al.   ARTIFICIAL ORGANS