Current knowledge on the genetics of incident venous thrombosis

A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis

(2013) Nicolas Greliche et al.   BMC Medical Genetics

Genetic Associations for Activated Partial Thromboplastin Time and Prothrombin Time, their Gene Expression Profiles, and Risk of Coronary Artery Disease

(2012) Weihong Tang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

ABO Blood Group and von Willebrand Factor Levels Partially Explained the Incomplete Penetrance of Congenital Thrombophilia

(2012) William Cohen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A Genome-Wide Association Study Identifies KNG1 as a Genetic Determinant of Plasma Factor XI Level and Activated Partial Thromboplastin Time

(2012) Maria Sabater-Lleal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Broadening the factor V Leiden paradox: pulmonary embolism and deep-vein thrombosis as 2 sides of the spectrum

(2012) K. van Langevelde et al.   BLOOD

The endothelial protein C receptor (PROCR) Ser219Gly variant and risk of common thrombotic disorders: a HuGE review and meta-analysis of evidence from observational studies

(2012) J. Dennis et al.   BLOOD

Multiple SNP testing improves risk prediction of first venous thrombosis

(2012) H. G. de Haan et al.   BLOOD

Identification of genetic risk variants for deep vein thrombosis by multiplexed next-generation sequencing of 186 hemostatic/pro-inflammatory genes

(2012) Luca A Lotta et al.   BMC Medical Genomics

Genome wide association study for plasma levels of natural anticoagulant inhibitors and protein C anticoagulant pathway: the MARTHA project

(2012) Tiphaine Oudot-Mellakh et al.   BRITISH JOURNAL OF HAEMATOLOGY

Venous Thrombosis in Blacks

(2012) Tyler W. Buckner et al.   CIRCULATION

Novel common and rare genetic determinants of paraoxonase activity:FTO,SERPINA12, andITGAL

(2012) Daniel S. Kim et al.   JOURNAL OF LIPID RESEARCH

Low borderline plasma levels of antithrombin, protein C and protein S are risk factors for venous thromboembolism

(2012) P. BUCCIARELLI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q

(2012) J. A. HEIT et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Large-scale association analysis identifies new risk loci for coronary artery disease

(2012) Panos Deloukas et al.   NATURE GENETICS

Low-Dose Aspirin for Preventing Recurrent Venous Thromboembolism

(2012) Timothy A. Brighton et al.   NEW ENGLAND JOURNAL OF MEDICINE

Aspirin for Preventing the Recurrence of Venous Thromboembolism

(2012) Cecilia Becattini et al.   NEW ENGLAND JOURNAL OF MEDICINE

Thrombosis from a Prothrombin Mutation Conveying Antithrombin Resistance

(2012) Yuhri Miyawaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effect of Genetic Variation in STXBP5 and STX2 on von Willebrand Factor and Bleeding Phenotype in Type 1 von Willebrand Disease Patients

(2012) Janine E. van Loon et al.   PLoS One

Pregnancy-related venous thromboembolism: Risk and the effect of thromboprophylaxis

(2012) Federico Lussana et al.   THROMBOSIS RESEARCH

Assessment of Genetic Determinants of the Association of γ′ Fibrinogen in Relation to Cardiovascular Disease

(2011) Rehana S. Lovely et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

KNG1 Ile581Thr and susceptibility to venous thrombosis

(2011) P.-E. Morange et al.   BLOOD

Age- and Gender-Specific Familial Risks for Venous Thromboembolism

(2011) Bengt Zöller et al.   CIRCULATION

Association of Variation at the ABO Locus With Circulating Levels of Soluble Intercellular Adhesion Molecule-1, Soluble P-selectin, and Soluble E-selectin

(2011) Stefan Kiechl et al.   Circulation-Cardiovascular Genetics

New gene variants associated with venous thrombosis: a replication study in White and Black Americans

(2011) H. AUSTIN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Genetic variation within the anticoagulant, procoagulant, fibrinolytic and innate immunity pathways as risk factors for venous thromboembolism

(2011) J. A. HEIT et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Racial differences in venous thromboembolism

(2011) N. A. ZAKAI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

(2011) Manuel A Rivas et al.   NATURE GENETICS

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

(2011) Heribert Schunkert et al.   NATURE GENETICS

Genetics of Venous Thrombosis: Insights from a New Genome Wide Association Study

(2011) Marine Germain et al.   PLoS One

A Genome-Wide Association Study of the Protein C Anticoagulant Pathway

(2011) Georgios Athanasiadis et al.   PLoS One

Common Variants of Large Effect in F12, KNG1, and HRG Are Associated with Activated Partial Thromboplastin Time

(2010) Lorna M. Houlihan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Follow-Up Study of a Genome-wide Association Scan Identifies a Susceptibility Locus for Venous Thrombosis on Chromosome 6p24.1

(2010) Pierre-Emmanuel Morange et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo

(2010) Q. Cheng et al.   BLOOD

Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis

(2010) N. L. Smith et al.   BLOOD

Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study

(2010) W. Tang et al.   BLOOD

C4BPB/C4BPA is a new susceptibility locus for venous thrombosis with unknown protein S-independent mechanism: results from genome-wide association and gene expression analyses followed by case-control studies

(2010) A. Buil et al.   BLOOD

Clinical guidelines for testing for heritable thrombophilia

(2010) Trevor Baglin et al.   BRITISH JOURNAL OF HAEMATOLOGY

Once and Only Once

(2010) F.R. Rosendaal   CIRCULATION

Novel Associations of Multiple Genetic Loci With Plasma Levels of Factor VII, Factor VIII, and von Willebrand Factor

(2010) Nicholas L. Smith et al.   CIRCULATION

Effect of Genetic Variations in Syntaxin-Binding Protein-5 and Syntaxin-2 on von Willebrand Factor Concentration and Cardiovascular Risk

(2010) Janine E. van Loon et al.   Circulation-Cardiovascular Genetics

Updated Analysis of Gene Variants Associated With Deep Vein Thrombosis

(2010) Irene D. Bezemer   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A multi-stage multi-design strategy provides strong evidence that the BAI3 locus is associated with early-onset venous thromboembolism

(2010) G. ANTONI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The minor allele of GP6 T13254C is associated with decreased platelet activation and a reduced risk of recurrent cardiovascular events and mortality: results from the SMILE-Platelets project

(2010) J. D. SNOEP et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Impact on venous thrombosis risk of newly discovered gene variants associated with FVIII and VWF plasma levels

(2010) P.-E. MORANGE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The Value of Family History as a Risk Indicator for Venous Thrombosis

(2009) Irene D. Bezemer et al.   ARCHIVES OF INTERNAL MEDICINE

FVII, FVIIa, and Downstream Markers of Extrinsic Pathway Activation Differ by EPCR Ser219Gly Variant in Healthy Men

(2009) Helen A. Ireland et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Common susceptibility alleles are unlikely to contribute as strongly as the FV and ABO loci to VTE risk: results from a GWAS approach

(2009) D.-A. Tregouet et al.   BLOOD

Expression of terminal  2-6-linked sialic acid on von Willebrand factor specifically enhances proteolysis by ADAMTS13

(2009) R. T. McGrath et al.   BLOOD

Functional consequences of the prothrombotic SERPINC1 rs2227589 polymorphism on antithrombin levels

(2009) A. I. Anton et al.   HAEMATOLOGICA

Recommendations on Testing for Thrombophilia in Venous Thromboembolic Disease: a French Consensus Guideline

(2009)   JOURNAL DES MALADIES VASCULAIRES

APC resistance: biological basis and acquired influences

(2009) E. CASTOLDI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Targeted capture and massively parallel sequencing of 12 human exomes

(2009) Sarah B. Ng et al.   NATURE

Exome sequencing identifies the cause of a mendelian disorder

(2009) Sarah B Ng et al.   NATURE GENETICS

Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer

(2009) Laufey Amundadottir et al.   NATURE GENETICS

X-Linked Thrombophilia with a Mutant Factor IX (Factor IX Padua)

(2009) Paolo Simioni et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic diagnosis by whole exome capture and massively parallel DNA sequencing

(2009) Murim Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect Against Type 1 Diabetes

(2009) S. Nejentsev et al.   SCIENCE

Screening for thrombophilia and antithrombotic prophylaxis in pregnancy: Guidelines of the Italian Society for Haemostasis and Thrombosis (SISET)

(2009) Federico Lussana et al.   THROMBOSIS RESEARCH

Effects of race and ethnicity on the incidence of venous thromboembolism

(2009) Richard H. White et al.   THROMBOSIS RESEARCH

The Epidemiology of Venous Thromboembolism in the Community

(2008) John A. Heit   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Advances in understanding pathogenic mechanisms of thrombophilic disorders

(2008) B. Dahlback   BLOOD

Gene Variants Associated With Deep Vein Thrombosis

(2008) Irene D. Bezemer   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

PROC,PROCRandPROS1polymorphisms, plasma anticoagulant phenotypes, and risk of cardiovascular disease and mortality in older adults: the Cardiovascular Health Study

(2008) A. P. REINER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Proof of principle of potential clinical utility of multiple SNP analysis for prediction of recurrent venous thrombosis

(2008) A. VAN HYLCKAMA VLIEG et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

African-American ethnicity is associated with higher plasma levels of D-dimer in adults with hypertension

(2008) M. KHALEGHI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Triggers, targets and treatments for thrombosis

(2008) Nigel Mackman   NATURE

Alternative mRNA is favored by the A3 haplotype of the EPCR gene PROCR and generates a novel soluble form of EPCR in plasma

(2007) B. Saposnik et al.   BLOOD