The abnormal proplatelet formation in MYH9-related macrothrombocytopenia results from an increased actomyosin contractility and is rescued by myosin IIA inhibition

Microtubule and cortical forces determine platelet size during vascular platelet production

(2012) Jonathan N Thon et al.   Nature Communications

RUNX1-induced silencing of non-muscle myosin heavy chain IIB contributes to megakaryocyte polyploidization

(2012) Larissa Lordier et al.   Nature Communications

Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A

(2011) Y. Zhang et al.   BLOOD

Enucleation of human erythroblasts involves non-muscle myosin IIB

(2011) K. Ubukawa et al.   BLOOD

Recent advances in the understanding and management of MYH9-related inherited thrombocytopenias

(2011) Carlo L. Balduini et al.   BRITISH JOURNAL OF HAEMATOLOGY

A new micropatterning method of soft substrates reveals that different tumorigenic signals can promote or reduce cell contraction levels

(2011) Qingzong Tseng et al.   LAB ON A CHIP

Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes

(2011) J.-W. Shin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations responsible for MYH9-related thrombocytopenia impair SDF-1-driven migration of megakaryoblastic cells

(2011) Valeria Bozzi et al.   THROMBOSIS AND HAEMOSTASIS

Advances in the understanding of MYH9 disorders

(2010) Shinji Kunishima et al.   CURRENT OPINION IN HEMATOLOGY

Proplatelet formation deficit and megakaryocyte death contribute to thrombocytopenia in Myh9 knockout mice

(2010) A. ECKLY et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9

(2009) L. Gilles et al.   BLOOD

MYH9related disease: four novel mutations of the tail domain of myosin-9 correlating with a mild clinical phenotype

(2009) Alessandro Pecci et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Regulation of megakaryocyte maturation and platelet formation

(2009) D. BLUTEAU et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

MYH9-Related Platelet Disorders

(2009) Karina Althaus et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Abnormal megakaryocyte morphology and proplatelet formation in mice with megakaryocyte-restricted MYH9 inactivation

(2008) A. Eckly et al.   BLOOD

Differential expression of wild-type and mutant NMMHC-IIA polypeptides in blood cells suggests cell-specific regulation mechanisms in MYH9 disorders

(2008) S. Kunishima et al.   BLOOD

Multiple Regulatory Steps Control Mammalian Nonmuscle Myosin II Assembly in Live Cells

(2008) Mark T. Breckenridge et al.   MOLECULAR BIOLOGY OF THE CELL

Position of nonmuscle myosin heavy chain IIA (NMMHC-IIA) mutations predicts the natural history ofMYH9-related disease

(2007) Alessandro Pecci et al.   HUMAN MUTATION