Influence of the paraoxonase-1 Q192R genetic variant on clopidogrel responsiveness and recurrent cardiovascular events: a systematic review and meta-analysis
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Influence of the paraoxonase-1 Q192R genetic variant on clopidogrel responsiveness and recurrent cardiovascular events: a systematic review and meta-analysis
Authors
Keywords
-
Journal
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
Volume 10, Issue 7, Pages 1242-1251
Publisher
Wiley
Online
2012-04-22
DOI
10.1111/j.1538-7836.2012.04756.x
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The paraoxonase-1 pathway is not a major bioactivation pathway of clopidogrel in vitro
- (2012) V Ancrenaz et al. BRITISH JOURNAL OF PHARMACOLOGY
- Clarifying the importance of CYP2C19 and PON1 in the mechanism of clopidogrel bioactivation and in vivo antiplatelet response
- (2012) Inna Y. Gong et al. EUROPEAN HEART JOURNAL
- The influence of CYP2C19*2 and *17 on on-treatment platelet reactivity and bleeding events in patients undergoing elective coronary stenting
- (2012) Ankie M. Harmsze et al. Pharmacogenetics and Genomics
- Prevalence of poor biological response to clopidogrel
- (2012) Carine Labruyère et al. THROMBOSIS AND HAEMOSTASIS
- 332 Genetic testing for cyp2c19*2 but not for pon-1 qq carrier status predicts high on-clopidogrel platelet reactivity in patients undergoing percutaneous coronary interventions
- (2011) D. So et al. CANADIAN JOURNAL OF CARDIOLOGY
- Cytochromes P450 Catalyze Both Steps of the Major Pathway of Clopidogrel Bioactivation, whereas Paraoxonase Catalyzes the Formation of a Minor Thiol Metabolite Isomer
- (2011) Patrick M. Dansette et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Paraoxonase-1 Q192R Polymorphism and Antiplatelet Effects of Clopidogrel in Patients Undergoing Elective Coronary Stent Placement
- (2011) Dietmar Trenk et al. Circulation-Cardiovascular Genetics
- CYP2C19 But Not PON1 Genetic Variants Influence Clopidogrel Pharmacokinetics, Pharmacodynamics, and Clinical Efficacy in Post–Myocardial Infarction Patients
- (2011) Jean-Sébastien Hulot et al. Circulation-Cardiovascular Interventions
- PON1 Q192R and Clopidogrel: A Case of the Winner’s Curse or Inadequate Replication?
- (2011) J A Talameh et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Effect of Paraoxonase-1 Polymorphism on Clinical Outcomes in Patients Treated With Clopidogrel After an Acute Myocardial Infarction
- (2011) T Simon et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Predicting Clopidogrel Response Using DNA Samples Linked to an Electronic Health Record
- (2011) J T Delaney et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Paraoxonase 1 (PON1) Gene Variants Are Not Associated With Clopidogrel Response
- (2011) J P Lewis et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Impact of Genetic Polymorphisms and Drug – Drug Interactions on Clopidogrel and Prasugrel Response Variability
- (2011) V. Ancrenaz et al. CURRENT DRUG METABOLISM
- Antiplatelet agents for the treatment and prevention of atherothrombosis
- (2011) Carlo Patrono et al. EUROPEAN HEART JOURNAL
- No association of paraoxonase-1 Q192R genotypes with platelet response to clopidogrel and risk of stent thrombosis after coronary stenting
- (2011) D. Sibbing et al. EUROPEAN HEART JOURNAL
- CYP2C19 Genotype, Clopidogrel Metabolism, Platelet Function, and Cardiovascular Events
- (2011) Michael V. Holmes et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Clinical, Angiographic, and Genetic Factors Associated With Early Coronary Stent Thrombosis
- (2011) Guillaume Cayla et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- TCT-171: Cytochrome P450 2C19 Loss-Of-Function Genetic Variants but not Paraoxonase-1 Activity Modulate P2Y12 Blockade in Response to Clopidogrel Therapy
- (2011) JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- TCT-151: Paraoxonase-1 (PON1) Activity And PON1 Polymorphisms Have No Effect On Platelet Reactivity In Patients Treated With Clopidogrel
- (2011) JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- TCT-155: Genetic Determinants of Clopidogrel Responsiveness in Koreans
- (2011) JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- 2011 ACCF/AHA Focused Update Incorporated Into the ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction
- (2011) R. Scott Wright et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Influence of high-density lipoprotein and paraoxonase-1 on platelet reactivity in patients with acute coronary syndromes receiving clopidogrel therapy
- (2011) A. D. TSELEPIS et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Relationship between paraoxonase Q192R gene polymorphism and on-clopidogrel platelet reactivity over time in patients treated with percutaneous coronary intervention
- (2011) G. CAMPO et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Relationship between paraoxonase-1 activity, its Q192R genetic variant and clopidogrel responsiveness in the ADRIE study
- (2011) P. FONTANA et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Paraoxonase-1 and clopidogrel efficacy
- (2011) Thomas Cuisset et al. NATURE MEDICINE
- Impact of genetic variants on post-clopidogrel platelet reactivity in patients after elective percutaneous coronary intervention
- (2011) Orsolya Rideg et al. PHARMACOGENOMICS
- Reduced-Function CYP2C19 Genotype and Risk of Adverse Clinical Outcomes Among Patients Treated With Clopidogrel Predominantly for PCI
- (2010) Jessica L. Mega et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- The Effect of St Johnʼs Wort on the Pharmacodynamic Response of Clopidogrel in Hyporesponsive Volunteers and Patients: Increased Platelet Inhibition by Enhancement of CYP3A4 Metabolic Activity
- (2010) Wei C Lau et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Impact of Cytochrome P450 2C19 Loss-of-Function Polymorphism and of Major Demographic Characteristics on Residual Platelet Function After Loading and Maintenance Treatment With Clopidogrel in Patients Undergoing Elective Coronary Stent Placement
- (2010) Willibald Hochholzer et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Paraoxonase-1 is a major determinant of clopidogrel efficacy
- (2010) Heleen J Bouman et al. NATURE MEDICINE
- Proton Pump Inhibitors and Clopidogrel
- (2009) David N. Juurlink CIRCULATION
- Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite
- (2009) M. Kazui et al. DRUG METABOLISM AND DISPOSITION
- Association of Cytochrome P450 2C19 Genotype With the Antiplatelet Effect and Clinical Efficacy of Clopidogrel Therapy
- (2009) Alan R. Shuldiner JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Relationship of Paraoxonase 1 (PON1) Gene Polymorphisms and Functional Activity With Systemic Oxidative Stress and Cardiovascular Risk
- (2008) Tamali Bhattacharyya JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Influence of Omeprazole on the Antiplatelet Action of Clopidogrel Associated With Aspirin
- (2008) Martine Gilard et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started