Article
Radiology, Nuclear Medicine & Medical Imaging
Ieun Yoon, Jae Seok Bae, Jeongin Yoo, Dong Ho Lee, Se Hyung Kim
Summary: Studies suggest that compared to MDCT alone, MDCT combined with [F-18]FDG PET/MRI can improve the diagnostic accuracy for preoperative M staging and resectability in patients with recurrent gastric cancer, with a significant advantage in evaluating M staging.
EUROPEAN RADIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Kotaro Nomura, Mariko Fukui, Aritoshi Hattori, Takeshi Matsunaga, Kazuya Takamochi, Kenji Suzuki
Summary: Preoperative staging of lymph node metastasis in patients with non-small cell lung cancer and usual interstitial pneumonia is difficult due to false-positive imaging findings and clinical upstaging caused by inflammation. This study showed that the diagnostic performance of PET/CT in patients with interstitial pneumonia was lower than that in patients without interstitial pneumonia, and the accuracy of nodal staging was further decreased in patients with FDG uptake.
ANNALS OF THORACIC SURGERY
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Seyed Ali Mirshahvalad, Andres Kohan, Ur Metser, Ricarda Hinzpeter, Claudia Ortega, Adam Farag, Patrick Veit-Haibach
Summary: This study conducted a diagnostic meta-analysis to evaluate the performance of [F-18]FDG PET/MR in M staging of [F-18]FDG-avid cancer entities. The results showed that [F-18]FDG PET/MR is highly accurate in detecting distant metastasis and has high sensitivity and specificity in various malignancy types. These findings provide clinicians and patients with confidence in the performance of [F-18]FDG PET/MR in clinical practice.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Francesca Marturano, Priscilla Guglielmo, Andrea Bettinelli, Fabio Zattoni, Giacomo Novara, Alessandra Zorz, Matteo Sepulcri, Michele Gregianin, Marta Paiusco, Laura Evangelista
Summary: Radiomic analysis can assist in predicting biochemical recurrence in intermediate and high-risk prostate cancer patients. Combining clinical data with radiomic features improves the accuracy of prediction.
EUROPEAN RADIOLOGY
(2023)
Article
Medicine, General & Internal
Roelof J. Beukinga, Floris B. Poelmann, Gursah Kats-Ugurlu, Alain R. Viddeleer, Ronald Boellaard, Robbert J. De Haas, John Th M. Plukker, Jan Binne Hulshoff
Summary: This study demonstrates that a radiomic model using baseline F-18-FDG PET can predict non-response to neoadjuvant chemoradiotherapy in esophageal cancer patients, providing a potential clinical benefit.
Article
Surgery
Jessie R. Elliott, Sheraz Markar, Fredrik Klevebro, Asif Johar, Lucas Goense, Pernilla Lagergren, Giovanni Zaninotto, Richard I. van Hillegersberg, Mark van Berge Henegouwen, Magnus B. Nilsson, George V. Hanna, John Reynolds
Summary: Regular surveillance after curative surgery for esophageal cancer has a significant impact on the recurrence pattern, treatment, survival, and quality of life. Intensive surveillance reduces symptomatic recurrence and increases tumor-directed therapy, particularly in patients with early-stage disease or favorable pathological stage. No overall survival benefit was observed, but improved survival was seen in select patient cohorts.
Editorial Material
Oncology
Hannah M. Linden, David A. Mankoff
Summary: [F-18]fluoroestradiol (FES) PET is an FDA-approved imaging biomarker that predicts clinical benefit of endocrine therapy and measures target activity in drug development. A recent study showed that tumor heterogeneity of expression predicts clinical benefit, and serial FES monitoring can assess estrogen receptor blockade and posttreatment release.
CLINICAL CANCER RESEARCH
(2023)
Article
Medicine, General & Internal
Tae Hoon Lee, Hyun Gee Ryoo, Reeree Lee, Jin Chul Paeng, Hyunsoo Chung, Hak Jae Kim
Summary: This study aimed to compare the longitudinal location of endoscopically-defined gross tumor volume (GTV) and positron emission tomography-based metabolic tumor volume (MTV) of esophageal cancer. The results showed that the fixed absolute threshold method was more consistent and SUV of 2.5 was appropriate for esophageal tumors with a maximum SUV > 20. Endoscopic hemoclips were stable enough for use as fiducial markers.
Article
Oncology
Michael P. Flood, Joseph C. Kong, Toan Pham, Peadar S. Waters, Mikael Soucisse, Robert Ramsay, Hui-Li Wong, Catherine Mitchell, Michael Michael, Jacob J. McCormick, Satish K. Warrier, Tim Akhurst, Alexander G. Heriot
Summary: The study aimed to assess the ability of preoperative PET in predicting the histological grade of pseudomyxoma peritonei (PMP). The results showed that preoperative PET had a positive correlation with high-grade PMP and acceptable sensitivity and specificity as a diagnostic tool. Therefore, PET should be considered a useful adjunct to predict the histological grade in the staging of PMP patients.
Review
Radiology, Nuclear Medicine & Medical Imaging
Bandar Alwadani, Sergio Dall'Angelo, Ian N. Fleming
Summary: Lung cancer has the highest mortality rate among all tumor types, largely due to uncontrolled cellular proliferation. [F-18]FLT-PET offers a non-invasive method to accurately assess cell proliferation rates, improving the accuracy of diagnosis, staging, and therapy response evaluation for lung cancer.
INSIGHTS INTO IMAGING
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Kristine E. Fasmer, Ankush Gulati, Julie A. Dybvik, Kari S. Wagner-Larsen, Njal Lura, Oyvind Salvesen, David Forsse, Jone Trovik, Johanna M. A. Pijnenborg, Camilla Krakstad, Ingfrid S. Haldorsen
Summary: This study evaluated the diagnostic performance of four different preoperative imaging workups for predicting lymph node metastases in endometrial cancer. The results showed that selective use of [F-18]FDG-PET/CT in patients with high-risk MRI findings detected lymph node metastases better than MRI alone.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Nils Martin Bruckmann, Julian Kirchner, Lale Umutlu, Wolfgang Peter Fendler, Robert Seifert, Ken Herrmann, Ann-Kathrin Bittner, Oliver Hoffmann, Svjetlana Mohrmann, Christina Antke, Lars Schimmoeller, Marc Ingenwerth, Katharina Breuckmann, Andreas Stang, Christian Buchbender, Gerald Antoch, Lino M. Sawicki
Summary: This study compared the diagnostic performance of different imaging techniques in detecting bone metastases in patients with primary breast cancer. [F-18]FDG PET/MRI and MRI alone showed significantly higher sensitivity and specificity than CT and bone scintigraphy; CT and bone scintigraphy had lower sensitivity in detecting bone metastases and were prone to false-positive results.
EUROPEAN RADIOLOGY
(2021)
Article
Multidisciplinary Sciences
Ou Yamaguchi, Kyoichi Kaira, Ichiro Naruse, Yukihiro Umeda, Takeshi Honda, Satoshi Watanabe, Kosuke Ichikawa, Kazunari Tateishi, Norimitsu Kasahara, Tetsuya Higuchi, Kosuke Hashimoto, Shun Shinomiya, Yu Miura, Ayako Shiono, Atsuto Mouri, Hisao Imai, Kunihiko Iizuka, Tamotsu Ishizuka, Koichi Minato, Satoshi Suda, Hiroshi Kagamu, Keita Mori, Ichiei Kuji, Nobuhiko Seki
Summary: This study aimed to investigate the clinical relevance of F-18-FDG PET/CT compared to CT in predicting the response to PD-1 blockade in the early phase. The results showed that metabolic assessment by MTV or TLG was superior to morphological changes on CT for predicting the therapeutic response and survival.
SCIENTIFIC REPORTS
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Sangwon Han, Joon Young Choi
Summary: The systematic review and meta-analysis found that the use of F-18-FDG PET, PET/CT, or PET/MRI during the initial staging of breast cancer can significantly modify staging and treatment plans for patients. Factors such as age, initial stage, and histologic grade were identified as significant factors affecting the heterogeneity in changes in stage or management. Routine clinical use of PET imaging for initial staging of breast cancer may be beneficial based on current literature.
CLINICAL NUCLEAR MEDICINE
(2021)
Review
Oncology
Felix T. Kurz, Heinz -Peter Schlemmer
Summary: This review aims to present recent advancements in translational cancer imaging research, specifically focusing on novel, recently established, or soon to be established cross-sectional imaging techniques such as computed tomography (CT), magnetic resonance imaging (MRI), and positron-emission tomography (PET), as well as computational investigations based on machine-learning techniques.
CANCER BIOLOGY & MEDICINE
(2022)
Article
Gastroenterology & Hepatology
A. M. Horgan, G. Darling, R. Wong, M. Guindi, G. Liu, D. J. Jonker, J. Lister, W. Xu, H. M. MacKay, R. Dinniwell, J. Kim, A. Pierre, Y. Shargall, T. R. Asmis, O. Agboola, A. J. Seely, J. Ringash, J. Wells, E. C. Marginean, M. Haider, J. J. Knox
DISEASES OF THE ESOPHAGUS
(2017)
Article
Cardiac & Cardiovascular Systems
Biniam Kidane, Joanne Sulman, Wei Xu, Qin Kong, Rebecca Wong, Jennifer J. Knox, Gail E. Darling
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2017)
Letter
Oncology
Edward Chow, Ralph M. Meyer, Keyue Ding, Abdenour Nabid, Pierre Chabot, Philip Wong, Shahida Ahmed, Joda Kuk, A. Rashid Dar, Aamer Mahmud, Alysa Fairchild, Carolyn F. Wilson, Jackson S. Y. Wu, Kristopher Dennis, Michael Brundage, Carlo DeAngelis, Rebecca K. S. Wong
Article
Health Care Sciences & Services
Srinivas Raman, Keyue Ding, Edward Chow, Ralph M. Meyer, Abdenour Nabid, Pierre Chabot, Genevieve Coulombe, Shahida Ahmed, Joda Kuk, A. Rashid Dar, Aamer Mahmud, Alysa Fairchild, Carolyn F. Wilson, Jackson S. Y. Wu, Kristopher Dennis, Carlo DeAngelis, Rebecca K. S. Wong, Liting Zhu, Michael Brundage
QUALITY OF LIFE RESEARCH
(2016)
Article
Oncology
Edward Chow, Keyue Ding, Wendy R. Parulekar, Rebecca K. S. Wong, Yvette M. van der Linden, Daniel Roos, William F. Hartsell, Peter Hoskin, Jackson S. Y. Wu, Abdenour Nabid, Jan Willem Leer, Ernest Vonk, Scott Babington, William F. Demas, Carolyn F. Wilson, Michael Brundage, Liting Zhu, Ralph M. Meyer
RADIOTHERAPY AND ONCOLOGY
(2016)
Article
Oncology
Lachlan J. McDowell, Shao Hui Huang, Wei Xu, Jiahua Che, Rebecca K. S. Wong, James Brierley, John Kim, Bernard Cummings, John Waldron, Andrew Bayley, Aaron Hansen, Ian Witterick, Jolie Ringash
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
(2017)
Article
Oncology
Andrew McPartlin, Anand Swaminath, Ri Wang, Melania Pintilie, James Brierley, John Kim, Jolie Ringash, Rebecca Wong, Rob Dinniwell, Tim Craig, Laura A. Dawson
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
(2017)
Article
Oncology
Michael Velec, Carol R. Haddad, Tim Craig, Lisa Wang, Patricia Lindsay, James Brierley, Anthony Brade, Jolie Ringash, Rebecca Wong, John Kim, Laura A. Dawson
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
(2017)
Article
Oncology
Rebecca B. Goody, Anthony M. Brade, Lisa Wang, Tim Craig, James Brierley, Robert Dinniwell, Rebecca K. S. Wong, Charles Cho, John Kim, Zahra Kassam, Jolie Ringash, Jennifer J. Knox, Laura A. Dawson
RADIOTHERAPY AND ONCOLOGY
(2017)
Article
Oncology
Rachel McDonald, Keyue Ding, Michael Brundage, Ralph M. Meyer, Abdenour Nabid, Pierre Chabot, Genevieve Coulombe, Shahida Ahmed, Joda Kuk, A. Rashid Dar, Aamer Mahmud, Alysa Fairchild, Carolyn F. Wilson, Jackson S. Y. Wu, Kristopher Dennis, Carlo DeAngelis, Rebecca K. S. Wong, Liting Zhu, Stephanie Chan, Edward Chow
Article
Oncology
Ronald Chow, Keyue Ding, Vithusha Ganesh, Ralph M. Meyer, Yvette M. van der Linden, Daniel Roos, William F. Hartsell, Peter Hoskin, Jackson S. Y. Wu, Abdenour Nabid, Manouk van Acht, Rinus Wanders, Scott Babington, William F. Demas, Carolyn F. Wilson, Rebecca K. S. Wong, Michael Brundage, Liting Zhu, Edward Chow
RADIOTHERAPY AND ONCOLOGY
(2018)
Article
Oncology
Stephen Lutz, Tracy Balboni, Joshua Jones, Simon Lo, Joshua Petit, Shayna E. Rich, Rebecca Wong, Carol Hahn
PRACTICAL RADIATION ONCOLOGY
(2017)
Article
Oncology
S. Singh, D. Sivajohanathan, T. Asmis, C. Cho, N. Hammad, C. Law, R. Wong, K. Zbuk
Article
Oncology
Aisling Barry, Andrew McPartlin, Patricia Lindsay, Lisa Wang, James Brierley, John Kim, Jolie Ringash, Rebecca Wong, Rob Dinniwell, Tim Craig, Laura A. Dawson
PRACTICAL RADIATION ONCOLOGY
(2017)
Review
Medicine, General & Internal
May N. Tsao, Wei Xu, Rebecca K. S. Wong, Nancy Lloyd, Normand Laperriere, Arjun Sahgal, Eileen Rakovitch, Edward Chow
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2018)