Review
Surgery
Bathiya Ratnayake, Sayali A. Pendharkar, Saxon Connor, Jonathan Koea, Diana Sarfati, Elizabeth Dennett, Sanjay Pandanaboyana, John A. Windsor
Summary: Contemporary literature confirms a strong relationship between patient volume and clinical outcomes for pancreatic cancer resection, with high-volume centers showing lower mortality, morbidity, failure-to-rescue, and positive resection margin rates.
Article
Health Care Sciences & Services
Seung Hyun Baik, So Yeon Kim, Young Cheol Na, Jin Mo Cho
Summary: The study evaluates the survival benefits of additional resection, including lobectomy, in patients with glioblastoma undergoing supratotal resection (SupTR). The results show that SupTR with lobectomy leads to superior progression-free survival (PFS) and overall survival (OS) without negatively affecting patient performance. The O6-DNA-methylguanine methyltransferase (MGMT) promoter methylation status is identified as a predictor for both superior PFS and OS.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Gastroenterology & Hepatology
Remy Sindayigaya, Stylianos Tzedakis, Ecoline Tribillon, Chloe Gavignet, Alessandro Mazzotta, Alexandra Nassar, Ugo Marchese, Olivier Soubrane, David Fuks
Summary: This study found that achieving TO could serve as a relevant surrogate marker for improved oncological care following SLHCC resection in non-cirrhotic patients.
Article
Surgery
Felice Giuliante, Francesco Ardito, Luca Aldrighetti, Alessandro Ferrero, Antonio D. Pinna, Luciano De Carlis, Umberto Cillo, Elio Jovine, Nazario Portolani, Salvatore Gruttadauria, Vincenzo Mazzaferro, Marco Massani, Edoardo Rosso, Giuseppe M. Ettorre, Francesca Ratti, Alfredo Guglielmi, Matteo Cescon, Marco Colasanti, Stefano Di Sandro, Enrico Gringeri, Nadia Russolillo, Andrea Ruzzenente, Carlo Sposito, Matteo Zanello, Giuseppe Zimmitti
Summary: Preoperative biliary drainage is crucial in reducing the risk of postoperative liver failure for perihilar cholangiocarcinoma patients undergoing hepatectomy, but it may also increase the risk of postoperative mortality due to infectious complications. The failure rate of preoperative biliary drainage was significantly higher at community hospitals, and failure was identified as an independent predictor for postoperative outcomes.
Article
Multidisciplinary Sciences
Julia Fuchs, Martin Frueh, Alexandros Papachristofilou, Lukas Bubendorf, Pirmin Haeuptle, Lorenz Jost, Alfred Zippelius, Sacha Rothschild
Summary: The study investigated the prognosis of NSCLC patients with resected brain metastases and identified postoperative cerebral radiotherapy, multiple brain metastases, and extracerebral metastases as significant prognostic factors. Patients who underwent postoperative radiotherapy had better survival outcomes, while those with multiple brain metastases or extracerebral metastases had shorter survival times.
Review
Health Care Sciences & Services
Ashutosh Kumar Singh, Nikita Khanal, Nisha Acharya, Md Riasat Hasan, Takashi Saito
Summary: Autotransplantation of teeth shows high success rates, with a 1-year survival rate of 97.4-98.0% and a 5-year survival rate of 81-98.2%. Major complications such as ankylosis and infection-related root resorption have low rates. Well-designed comparative studies with long-term follow-up are recommended to validate the results.
Article
Medicine, General & Internal
Lea Penzkofer, Jens Mittler, Stefan Heinrich, Nicolas Wachter, Beate K. Straub, Roman Kloeckner, Fabian Stoehr, Simon Johannes Gairing, Fabian Bartsch, Hauke Lang
Summary: Liver cirrhosis is a common risk factor for hepatocellular carcinoma (HCC), but a small percentage of HCC cases occur in non-cirrhotic livers. This study found that liver resection for non-cirrhotic HCC is an acceptable treatment approach with relatively good outcomes, even for extensive tumors.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Pediatrics
Roberto Tambucci, Catherine de Magnee, Margot Szabo, Aniss Channaoui, Aurore Pire, Vanessa de Meester de Betzenbroeck, Isabelle Scheers, Xavier Stephenne, Francoise Smets, Etienne M. Sokal, Raymond Reding
Summary: The sequential strategy of performing KP followed by LT allows for liver transplantation in older patients with better clinical conditions compared to those without prior KP. Patient and graft survival rates were not affected by previous KP, supporting the current strategy based on sequential treatment.
FRONTIERS IN PEDIATRICS
(2021)
Article
Clinical Neurology
Stephen T. Magill, Minh P. Nguyen, Manish K. Aghi, Philip Theodosopoulos, Javier E. Villanueva-Meyer, Michael W. McDermott
Summary: A DWI signal > 1 cm is significantly associated with postoperative neurological deficits, both immediate and long-lasting. Greater estimated blood loss, older age, tumor location over the motor strip, and preoperative peri-tumoral edema increase the risk of having a postoperative DWI signal > 1 cm, reflective of perilesional ischemia. Most immediate postoperative deficits will improve over time.
JOURNAL OF NEUROSURGERY
(2021)
Article
Oncology
Franziska Willis, Julian Musa, Simon Schimmack, Ulf Hinz, Gunhild Mechtersheimer, Matthias Uhl, Thomas Schmidt, Stefan Froehling, Markus W. Buechler, Martin Schneider
Summary: LR and DM are common in RPS with longer time to recurrence and resection of recurrence associated with improved OS for first and second LR. Gross macroscopic incomplete resection of first, second, and third recurrences is an independent poor prognostic factor for OS. Patients benefit from tumor resection not only in case of first, but also in case of subsequent recurrences.
Article
Oncology
Floris S. Verheij, Kevin C. Soares, Geerard L. Beets, Niels F. M. Kok, Jonathan B. Yuval, Nancy E. Kemeny, T. Peter Kingham, William R. Jarnagin, Michael D'Angelica, Julio Garcia-Aguilar
Summary: Simultaneous HAIP implantation and colectomy is safe in patients with liver metastases of colon carcinoma, with higher rates of grade 1-2 complications but no difference in grade 3-4 complications compared to HAIP placement alone. The median interval between HAIP placement and start of HAIP chemotherapy was similar between the two groups, and infection of the pump causing delay of initiation of chemotherapy or pump explantation was not significantly different between the groups.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Article
Oncology
Gaya Spolverato, Giulia Capelli, Giulia Lorenzoni, Dario Gregori, Jin He, Irinel Popescu, Hugo P. Marques, Luca Aldrighetti, Shishir K. Maithel, Carlo Pulitano, Todd W. Bauer, Feng Shen, George A. Poultsides, Oliver Soubrane, Guillaume Martel, Bas Groot Koerkamp, Endo Itaru, Yi Lv, Timothy M. Pawlik
Summary: The study aimed to develop a dynamic prognostic model for patients undergoing curative-intent resection for intrahepatic cholangiocarcinoma (ICC) using landmark analysis. The model incorporated selected variables and their interaction with time to predict overall survival (OS) over time. The model demonstrated good discrimination ability and accuracy in internal validation.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Article
Surgery
Hyun Jin Bae, Hoyeon Ju, Han Hee Lee, Jinsu Kim, Bo-In Lee, Sung Hak Lee, Daeyoun David Won, Yoon Suk Lee, In Kyu Lee, Young-Seok Cho
Summary: This study compared the long-term outcomes of T1 colorectal cancer patients treated with different methods. It found that ER prior to surgery did not affect the prognosis of high-risk T1 CRC patients, and did not worsen the clinical outcomes of patients who required additional surgery. Lymphatic invasion was identified as the most important predictor of lymph node metastasis.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Multidisciplinary Sciences
Yixin Wen, Feng Xu, Yang Liu, Kaining Zhi, Junfeng Tan, Yong Jiang, Minghui Li, Hui Zhang
Summary: This study investigated the clinical outcomes of preserving or excising the infrapatellar fat pad (IPFP) during anterior cruciate ligament reconstruction (ACLR). The results showed that preserving IPFP led to more significant improvements in anterior knee pain and knee joint function compared to excising IPFP. Surgeons should avoid excising IPFP as much as possible to ensure the effectiveness of ACLR.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Han-Ki Lim, Minjung Kim, Ji Won Park, Seung-Bum Ryoo, Kyu Joo Park, Nam-Joon Yi, Kwang-Woong Lee, Kyung-Suk Suh, Heung-Kwon Oh, Duck-Woo Kim, Sung-Bum Kang, Jai Young Cho, Dong-Woon Lee, Sung Chan Park, Jae Hwan Oh, Aesun Shin, Seung-Yong Jeong
Summary: This study aimed to compare the short- and long-term outcomes of simultaneous laparoscopic, hybrid, and open resection for colorectal cancer and synchronous liver metastases. The results showed that simultaneous laparoscopic resection can be performed safely with enhanced postoperative recovery and comparable long-term outcomes compared to hybrid and open resection.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Asgeir Alexandersson, Thora Steingrimsdottir, Jeremy Terrien, Catherine Marque, Brynjar Karlsson
Article
Engineering, Biomedical
Malunoud Hassan, Jeremy Terrien, Charles Muszynski, Asgeir Alexandersson, Catherine Marque, Brynjar Karlsson
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2013)
Article
Biochemistry & Molecular Biology
Francesco Maria Petrini, Marko Bumbasirevic, Giacomo Valle, Vladimir Ilic, Pavle Mijovic, Paul Cvancara, Federica Barberi, Natalija Katic, Dario Bortolotti, David Andreu, Knut Lechler, Aleksandar Lesic, Sanja Mazic, Bogdan Mijovic, David Guiraud, Thomas Stieglitz, Asgeir Alexandersson, Silvestro Micera, Stanisa Raspopovic
Article
Cell Biology
Francesco Maria Petrini, Giacomo Valle, Marko Bumbasirevic, Federica Barberi, Dario Bortolotti, Paul Cvancara, Arthur Hiairrassary, Pavle Mijovic, Atli Orn Sverrisson, Alessandra Pedrocchi, Jean-Louis Divoux, Igor Popovic, Knut Lechler, Bogdan Mijovic, David Guiraud, Thomas Stieglitz, Asgeir Alexandersson, Silvestro Micera, Aleksandar Lesic, Stanisa Raspopovic
SCIENCE TRANSLATIONAL MEDICINE
(2019)
Review
Orthopedics
Vigdis Vala Valgeirsdottir, Jona Sigrun Sigurdardottir, Knut Lechler, Lisa Tronicke, Omar Johannesson, Asgeir Alexandersson, Arni Kristjansson
Summary: This review provides an overview of performance-based measures for lower-limb neuroprosthetic systems and evaluates their utility. The results indicate the urgent need for further development of performance tests, metrics, and strategies specifically designed for the evaluation of these systems.
JOURNAL OF PROSTHETICS AND ORTHOTICS
(2022)
Proceedings Paper
Engineering, Biomedical
Catherine Marque, Jeremy Laforet, Chiara Rabotti, Asgeir Alexandersson, Guy Germain, Jean Gondry, Brynjar Karlsson, Brane Leskosek, Massimo Mischi, Charles Muszinski, Guid Oei, Jan Peuscher, Drago Rudel
2013 35TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)
(2013)
Article
Medicine, General & Internal
Tomas Andri Axelsson, Martin Ingi Sigurosson, Asgeir Alexandersson, Hunbogi Porsteinsson, Guomundur Klemenzson, Steinn Jonsson, Tomas Guobjartsson
Article
Medicine, General & Internal
Asgeir Alexandersson, Steinn Jonsson, Helgi J. Isaksson, Tomas Guobjartsson