Article
Surgery
S. Lau, J. Kong, S. Bell, A. Heriot, A. Stevenson, J. Moloney, J. Hayes, A. Merrie, T. Eglinton, G. Guest, D. Clark, S. Warrier
Summary: This study demonstrated that skilled minimally invasive rectal cancer surgeons in Australia and New Zealand can achieve similar pathological and oncological outcomes with taTME as compared to open and laparoscopic surgeries, indicating high safety levels with appropriate training and supervision.
BRITISH JOURNAL OF SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Supreet P. Marathe, Ajay J. Iyengar, Kim S. Betts, Karin du Plessis, Gananjay G. Salve, Robert N. Justo, Prem Venugopal, David S. Winlaw, Yves d'Udekem, Nelson Alphonso
Summary: Fontan takedown is a rare but high-risk procedure, with majority of cases occurring within 6 months post-surgery and highest mortality between 3 weeks and 6 months. A small proportion of survivors may undergo a second Fontan procedure.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Review
Surgery
Supreet P. Marathe, Jessica Suna, Kim S. Betts, Greg Merlo, Igor E. Konstantinov, Ajay J. Iyengar, Prem Venugopal, Nelson Alphonso
Summary: There is a lack of a database for congenital cardiac surgery in Australia and New Zealand (ANZ), leading to the establishment of ANZ Congenital Outcomes Registry for Surgery (ANZCORS). An analysis of data from 2015 to 2019 showed a low 30-day mortality rate and similar surgical outcomes among the participating centers.
ANZ JOURNAL OF SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Kim S. Betts, Supreet P. Marathe, Kevin Chai, Igor Konstantinov, Ajay Iyengar, Jessica Suna, Prem Venugopal, Nelson Alphonso
Summary: The study aims to develop a risk prediction model for 30-day mortality in the Australian and New Zealand patient populations and compare the performance of machine learning algorithms with traditional statistical methods. The gradient-boosted tree method showed the best performance, outperforming penalized logistic regression and artificial neural networks. The strongest predictors of mortality in the gradient boosting trees were patient weight, STAT score, age, and gender.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Puja Gaur Khaitan, Andrew M. Vekstein, Dylan Thibault, Andrzej Kosinski, Matthew G. Hartwig, Mark Block, Henning Gaissert, Andrea S. Wolf
Summary: A recent study evaluated the trends in esophagectomy and found that minimally invasive and robotic-assisted surgeries have become the dominant approach. While these approaches have higher rates of complications, there is no significant difference in operative mortality. Further studies are needed to assess long-term outcomes and cancer treatment effects.
ANNALS OF THORACIC SURGERY
(2023)
Article
Endocrinology & Metabolism
Marilyne Daher, Jeena Varghese, Stephen K. Gruschkus, Camilo Jimenez, Steven G. Waguespack, Sara Bedrose, Lina Altameemi, Hadil Bazerbashi, Aung Naing, Vivek Subaiah, Matthew T. Campbell, Amishi Y. Shah, Miao Zhang, Rahul A. Sheth, Jose A. Karam, Christopher G. Wood, Nancy D. Perrier, Paul H. Graham, Jeffery E. Lee, Mouhammed Amir Habra
Summary: This study reports that the disease burden and clinical outcomes of adrenocortical carcinoma (ACC) have improved over the past two decades. More patients underwent complete surgical resection and received multiple lines of systemic therapy, indicating the importance of these advancements for guiding management strategies.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Medicine, General & Internal
Odette Hart, Shirley Jansen, Robert Fitridge, Manar Khashram
Summary: Diabetic foot disease is a common and serious condition globally, especially among indigenous populations, leading to concerns about limb amputation. This multicentre study aims to prospectively report on the presentation, management, and outcomes of diabetic foot disease, validate existing scoring systems, and assess long-term outcomes, particularly in relation to major limb amputation.
Article
Medicine, General & Internal
Nasser Sakran, Shiri Sherf-Dagan, Keren Hod, Uri Kaplan, Bella Azaria, Asnat Raziel, Assuta Bariatric Surg Collaborative
Summary: This study investigated the <= 30-day outcomes of one-anastomosis gastric bypass (OAGB) used in primary (pOAGB) and revisional (rOAGB) procedures, and identified predictors of early complications. The results showed that OAGB is a safe procedure with common complications including bleeding, leaks, and obstruction/stricture.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Kathleen Colman, Tarek Alsaied, Adam Lubert, Harry B. Rossiter, Wayne A. Mays, Adam W. Powell, Sandra Knecht, Danielle Poe, Nicholas Ollberding, Zhiqian Gao, Clifford Chin, Gruschen R. Veldtman
Summary: The study demonstrates a strong association between elevated peripheral venous pressure (PVP) during exercise and adverse outcomes in Fontan patients. Monitoring PVP during exercise could be a useful tool for identifying individuals at higher risk for Fontan-related morbidities.
Article
Cardiac & Cardiovascular Systems
Evaldas Girdauskas, Johannes Petersen, Uemniye Balaban, Eva Herrmann, Timm Bauer, Andreas Beckmann, Raffi Bekeredjian, Stephan Ensminger, Christian Frerker, Helge Moellmann, Thomas Walther, Sabine Bleiziffer
Summary: AV repair/AV-sparing root surgery is an effective strategy for treating young patients with aortic regurgitation and/or aortic root aneurysm. This study analyzed real-world data from the German Aortic Valve Registry and found that the surgical procedure resulted in satisfactory clinical outcomes, including high survival rates and freedom from cardiac adverse events at one year. Additionally, the specific surgical technique used did not significantly impact the outcomes.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Medicine, General & Internal
Antonio Maria Fea, Martina Menchini, Alessandro Rossi, Chiara Posarelli, Lorenza Malinverni, Michele Figus
Summary: The study investigated the efficacy and safety of the XEN63 implant in open-angle glaucoma patients, showing significant reduction in intraocular pressure and the need for hypotensive medications, with good short-term safety profile.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Clinical Neurology
Carlos Garcia-Esperon, Teddy Y. Wu, Vinicius Carraro do Nascimento, Bernard Yan, Craig Kurunawai, Tim Kleinig, Gregory Selkirk, David Blacker, P. Alan Barber, Annemarei Ran, Alvaro Cervera, Andrew Wong, Peter Mitchell, Claire Muller, Hal Rice, Laetitia De Villiers, Jim Jannes, Jae Beom Hong, Peter Bailey, Helen Brown, Bruce C. Campbell, Duncan Wilson, John Fink, Timothy Ang, Christopher Bladin, Tim Phillip, Md Golam Hasnain, Kenneth Butcher, Ferdinand Miteff, Christopher R. Levi, Neil J. Spratt, Mark W. Parsons
Summary: This study retrospectively analyzed patients transferred for endovascular thrombectomy (EVT) and found that patients transferred over 300 miles can benefit from EVT, and the use of computed tomography perfusion (CTP) at the referring hospital can reduce poorer outcomes at 3 months.
Article
Cardiac & Cardiovascular Systems
Masaki Funamoto, Chandra Kunavarapu, Michael D. Kwan, Yuichi Matsuzaki, Mahek Shah, Masahiro Ono
Summary: This study retrospectively analyzed 70 patients who underwent Impella 5.5 implantation and showed that Impella 5.5 provides favorable survival in the management of acute decompensated heart failure and cardiogenic shock, particularly used as a bridge to heart transplant or LVAD.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Ophthalmology
Juliette A. Meyer, Robyn Troutbeck, Genevieve F. Oliver, Lynn K. Gordon, Helen V. Danesh-Meyer
Summary: The surveys commissioned by RANZCO revealed a high prevalence of DBSH among members, with female ophthalmologists being more likely to experience such behaviors. Low reporting rates were attributed to fear of impacting future career options, fear of victimization, and fear of not being believed.
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2021)
Article
Surgery
Swarna Vishwanath, Breanna Pellegrini, Emily Parker, Arul Earnest, Saeid Kalbasi, Pragya Gartoulla, Elisabeth Elder, Gillian Farrell, Colin Moore, Rodney D. Cooter, Susannah Ahern, John J. McNeil, Ingrid Hopper
Summary: The study reported on the characteristics of breast device surgery in Australia, including patient proportions, surgical techniques, and revision rates for complications post-surgery. High levels of patient satisfaction were reported, and early data from the ABDR indicate a promising development trend for the registry.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Jacob Y. Cao, Supreet P. Marathe, Diana Zannino, David S. Celermajer, Robert N. Justo, Nelson Alphonso, Yves d'Udekem, David S. Winlaw
Summary: Early Fontan operation does not pose a risk factor for short- or long-term adverse outcomes in our cohort.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Review
Pediatrics
Derek L. Tran, Hannah Gibson, Andrew J. Maiorana, Charlotte E. Verrall, David W. Baker, Melanie Clode, David R. Lubans, Diana Zannino, Andrew Bullock, Suzie Ferrie, Julie Briody, Peter Simm, Vishva Wijesekera, Michelle D'Almeida, Sally E. Gosbell, Glen M. Davis, Robert Weintraub, Anthony C. Keech, Rajesh Puranik, Martin Ugander, Robert Justo, Dominica Zentner, Avik Majumdar, Leeanne Grigg, Jeff S. Coombes, Yves d'Udekem, Norman R. Morris, Julian Ayer, David S. Celermajer, Rachael Cordina
Summary: Despite advancements in surgical techniques and medical care, people with a Fontan circulation still face long-term complications, indicating a need for non-invasive therapies to optimize circulation. Exercise intolerance is common among this population, but exercise training may be important for improving aerobic capacity and circulatory function in the setting of Fontan physiology. Further research is needed to fully understand the mechanisms behind these improvements and to determine optimal methods of exercise prescription.
FRONTIERS IN PEDIATRICS
(2022)
Review
Cardiac & Cardiovascular Systems
S. Watkins, O. Isichei, T. L. Gentles, R. Brown, T. Percival, L. Sadler, R. Gorinski, S. Crengle, E. Cloete, M. W. M. de Laat, F. H. Bloomfield, K. Ward
Summary: The experience of diagnosis, decision-making and management in critical congenital heart disease is complex and has a significant impact on families. This study synthesised the current evidence and identified three themes related to the family experience.
PEDIATRIC CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Jessica M. Suna, Supreet P. Marathe, Prem Venugopal, Robert Justo, Nelson Alphonso, Gregory Merlo, Lisa Hall
Summary: This study examined stakeholder preferences for paediatric cardiac surgery performance data in Australia and New Zealand, finding that mortality information was of greatest interest and that most preferred hospital-level reporting and annual reports distributed electronically.
CARDIOLOGY IN THE YOUNG
(2023)
Review
Cardiac & Cardiovascular Systems
David S. Celermajer, David W. Baker, Rachael L. Cordina, Michael Gatzoulis, Craig S. Broberg
Summary: Due to advances in cardiac care, more patients with congenital heart disease are able to reach adulthood. It is important for general cardiologists to have a good understanding of adult congenital heart disease, including common errors and when to refer to a specialist center. This review provides case studies to help healthcare providers address common issues in adult congenital heart disease.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Alexander D. Hussey, Thomas L. Gentles, Fiona Perelini, John Beca, Kirsten Finucane
Summary: The outcomes of emergency arterial switch operation (ASO) for infants with d-loop transposition of the great arteries and persistent pulmonary hypertension of the newborn were analyzed retrospectively. The emergency ASO group had higher 30-day postoperative mortality, but there was no significant difference in abnormal neurodevelopmental outcome among the survivors compared to the nonemergency group. The emergency group required more treatments for low cardiac output syndrome, experienced more postoperative seizures, and had a longer length of stay.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Nutrition & Dietetics
Nicholas A. Koemel, Alistair M. Senior, David S. Celermajer, Amanda Grech, Tim P. Gill, Stephen J. Simpson, David Raubenheimer, Michael R. Skilton
Summary: This study evaluated the associations between macronutrient intake and all-cause, cardiovascular, and cancer mortality. It found that a high-calorie diet consisting of moderately high protein, moderate fat, and moderate carbohydrate levels was associated with the highest mortality risk. Lower mortality risk was observed in two separate regions consisting of higher protein, higher carbohydrate, and lower fat levels or lower protein, moderate carbohydrate, and higher fat levels. These findings highlight the complex nonlinear and interactive association between macronutrients and all-cause mortality.
Article
Cardiac & Cardiovascular Systems
Benjamin Anderson, Robert Justo, Cameron Ward
Summary: This retrospective study analyzed the outcomes of using the Bentley BeGraft Aortic stent for the treatment of aortic arch pathology in children. The results showed that the stent can be safely deployed in children and has acceptable medium-term patency. However, larger and long-term follow-up studies are needed to assess its performance.
HEART LUNG AND CIRCULATION
(2023)
Article
Medicine, General & Internal
Natalie Soszyn, Elza Cloete, Lynn Sadler, Monique W. M. de laat, Sue Crengle, Frank Bloomfield, Kirsten Finucane, Thomas L. Gentles
Summary: This study retrospectively analyzed the relative influence of fetal and maternal factors on the choice-of-care pathway (CCP) and outcome in fetuses with hypoplastic left heart syndrome (HLHS). The study found that delayed diagnosis and ethnic disparities were related to prenatal decisions and postnatal outcomes, suggesting systemic inequity and the need for further investigation.
Review
Psychology, Developmental
Karen J. Eagleson, Desiree McCombs, Tiffany M. Gerlich, Robert N. Justo, Nadine A. Kasparian, Samudragupta Bora
Summary: This systematic review aims to identify instruments that quantitatively assess psychosocial adaptation and outcomes in families of children with congenital heart disease (CHD) and evaluate the psychometric properties of these instruments. The results show that there is a wide variation in the instruments used to assess psychosocial adaptation and outcomes among families of children with CHD. It is recommended to use instruments with robust key psychometrics for assessment and to improve the quality of psychometric reporting. The development of both a toolkit approach and a comprehensive CHD-specific family instrument are also among the key recommendations.
JOURNAL OF PEDIATRIC PSYCHOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Rachel Webb, Nicola Culliford-Semmens, Andrew ChanMow, Robert Doughty, Elizabeth Tilton, Briar Peat, John Stirling, Thomas L. Gentles, Nigel J. Wilson
Summary: A screening study conducted in an urban area of South Auckland, New Zealand, revealed a high prevalence of rheumatic heart disease (RHD) in adults, comparable to lower-middle-income countries in Africa. Non-rheumatic cardiac abnormalities were also identified.
Review
Medicine, Research & Experimental
Robyn W. May, Gonzalo Maso D. Talou, Alys R. Clark, Jonathan P. Mynard, Joseph J. Smolich, Pablo J. Blanco, Lucas O. Mueller, Thomas L. Gentles, Frank H. Bloomfield, Soroush Safaei
Summary: Computational modeling is widely used in the study of cardiovascular hemodynamics for medical research and improving the diagnosis and treatment of cardiovascular diseases. Most existing cardiovascular models focus on the adult circulatory system, but the perinatal period is unique as cardiovascular physiology undergoes significant changes. This review discusses computational models of the cardiovascular system in early life, their applications, and proposes a roadmap for developing an open-source model spanning fetal, perinatal, and postnatal periods.
WIRES MECHANISMS OF DISEASE
(2023)
Review
Clinical Neurology
Bridget R. Abell, Karen Eagleson, Benjamin Auld, Samudragupta Bora, Robert Justo, William Parsonage, Pakhi Sharma, Sanjeewa Kularatna, Steven M. McPhail
Summary: This scoping review identified and mapped the components of neurodevelopmental follow-up care for children with congenital heart disease (CHD). Common attributes of care pathways included enrolling high-risk children, centralized clinics, referral before discharge, periodic follow-up, standardized assessments, and multidisciplinary teams. Implementation barriers included financial resources, patient burden, and lack of knowledge. Stakeholder engagement and integration with other services were key drivers of success.
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Gautham Shetty, Jason Zouki, Geraldine Lee, Aditya Patukale, Kim S. Betts, Robert N. Justo, Supreet P. Marathe, Prem Venugopal, Nelson QPCR Grp, Nelson Alphonso
Summary: The study aimed to determine the incidence of pneumothorax and/or pleural effusion after chest drain removal following pediatric cardiac surgery. The results showed a low incidence of clinically significant pneumothorax/pleural effusion, with most patients not requiring chest drain reinsertion, suggesting that routine chest radiographs following chest drain removal may not be necessary for most pediatric cardiac surgical patients.
INTERDISCIPLINARY CARDIOVASCULAR AND THORACIC SURGERY
(2023)
Correction
Cardiac & Cardiovascular Systems
Gerald F. Watts, David R. Sullivan, David L. Hare, Karam M. Kostner, Ari E. Horton, Damon A. Bell, Tom Brett, Ronald J. Trent, Nicola K. Poplawski, Andrew C. Martin, Shubha Srinivasan, Robert N. Justo, Clara K. Chow, Jing Pang
AMERICAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2022)