Editorial Material
Biochemistry & Molecular Biology
Wendy P. Robinson, Giulia F. Del Gobbo
Summary: Mutations occurring early in human development are often seen in the placenta, providing insights into normal developmental processes leading to a healthy placenta. Despite similarities with cancer, these mutations are mainly confined to the placenta and not the embryo.
TRENDS IN MOLECULAR MEDICINE
(2021)
Article
Medicine, General & Internal
Nerea Lopez Perez, Philippe Reymond, Mustafa Cikirikcioglu, Mathieu van Steenberghe, Tornike Sologashvili, Nicolas Murith, Thomas Perneger, Christoph Huber
Summary: This study examines the ratio between ascending and descending aorta diameters as a potential surrogate marker for decision making in cases of ascending aortic dilatation. A retrospective observational cohort study was conducted on 50 patients who underwent surgery for acute type A aorta dissection. The results suggest that the ratio between descending and ascending aorta diameters may be a useful tool for stratifying the risk of dissection.
JOURNAL OF CLINICAL MEDICINE
(2023)
News Item
Multidisciplinary Sciences
Liam Drew
Summary: Researchers state that devices capable of recording and altering brain activity will present privacy concerns that question current human rights laws.
Article
Economics
Iryna Sotnyk, Tetiana Kurbatova, Andra Blumberga, Oleksandr Kubatko, Olha Prokopenko
Summary: The prosumerism of self-consuming green energy generated by small power producers plays a significant role in energy transition and sustainable development. This study fills the research gap on business solar self-consumption in a transitioning economy using Ukraine as an example, confirming the positive outcomes of the solar power sector.
Article
Critical Care Medicine
G. Luengo-Alonso, L. Garcia Lamas, V Jimenez Diaz, J. Ferrero Recasens, M. A. Porras Moreno, D. Cecilia Lopez
Summary: Proper surgical treatment of trans-olecranon fracture dislocations should focus on addressing any associated radial head and coronoid injuries, achieving proper ulnar fixation with dorsal angulation restoration. Clinical and functional outcomes suggest good results and functional recovery in patients post-surgery.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2021)
Article
Cardiac & Cardiovascular Systems
Jose M. Siurana, Anna Sabate-Rotes, Ariadna Ayerza, Lorenzo Jimenez, Marc Figueras-Coll, Maria Aranzazu Gonzalez
Summary: This study aimed to find the best reference tool to define dilation of the aortic root and the ascending aorta in BAV adolescents with an adult body surface area (BSA). The results indicate that in the ascending aorta, it is advisable to switch to BSA-IV when children are older than 10 years old and have a BSA >= 1.5 m2.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Review
Gastroenterology & Hepatology
Rebecca Dunn, Aaron Wetten, Stuart McPherson, Mhairi C. Donnelly
Summary: This article highlights the ongoing challenge of viral hepatitis worldwide and the ambitious goal set by the World Health Organization. It also summarizes the resolved and unresolved issues in the field, and suggests future directions for problem solving and research.
WORLD JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Surgery
Malek Barka, Mohamed Salah Jarrar, Jihene Sahli, Zied Ben Abdessalem, Fehmi Hamila, Sabri Youssef
Summary: This study aimed to evaluate the outcomes of early laparoscopic cholecystectomy (ELC) in patients with acute calculous cholecystitis (ACC) who had symptoms for more than 7 days. The results showed that there were no significant differences in conversion rate, intra- and postoperative complications, and length of stay between the two groups. Therefore, ELC could be considered as a treatment option for patients with ACC even after 7 days of symptoms.
LANGENBECKS ARCHIVES OF SURGERY
(2023)
Article
Clinical Neurology
Cheng-Fu Ni, Sho-Jen Cheng, Cheng-Yu Chen, Tu-Hsueh Yeh, Kevin Li-Chun Hsieh
Summary: This study demonstrates that rescue stent retriever therapy improves reperfusion rate in patients with acute ischemic stroke. However, patients requiring rescue therapy have lower likelihood of achieving functional independence. Large vessel occlusion in the anterior circulation responds better to rescue stent retriever therapy resulting in better functional outcomes compared to posterior circulation lesions.
FRONTIERS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Cheng-Fu Ni, Sho-Jen Cheng, Cheng-Yu Chen, Tu-Hsueh Yeh, Kevin Li-Chun Hsieh
Summary: The study demonstrates that rescue stent retriever therapy improves reperfusion rates, but patients requiring rescue therapy are less likely to achieve functional independence. Anterior circulation LVO responds better to rescue stent retriever therapy and results in better outcomes than posterior circulation lesions.
FRONTIERS IN NEUROLOGY
(2021)
Article
Transportation
Jung Eun Park
Summary: Cost overruns and schedule delays are common reasons for project failure. Despite efforts in project controls in the U.S. and U.K. over the last two decades, project performance has not improved from a schedule perspective. The study suggests using reference class forecasting for more realistic and reliable schedule estimates.
Article
Medicine, Research & Experimental
Chunhua Wang, Bo Wang, Zanmei Lv, Jia Zhi, Jie Yang, Yuqing Hao
Summary: Aortic dissection is a serious cardiovascular disease with complex and diverse symptoms, including severe tearing pain and atypical symptoms. The objective of this study is to enhance clinical understanding of painless aortic dissection, improve the ability for accurate diagnosis and timely treatment, and enhance patient outcomes.
EXPERIMENTAL AND THERAPEUTIC MEDICINE
(2022)
Review
Biochemistry & Molecular Biology
Wil Prall, Diep R. Ganguly, Brian D. Gregory
Summary: Although covalent nucleotide modifications were first identified on tRNAs and rRNAs, they have also been found on mRNAs. These modifications have significant effects on the processing and functionality of these protein-encoding molecules. This article focuses on the understanding, detection, and study of covalent nucleotide modifications on mRNAs in plants, as well as the outstanding future questions in this field.
Article
Cardiac & Cardiovascular Systems
Piergiorgio Tozzi, Ziyad Gunga, Lars Niclauss, Dominique Delay, Aurelian Roumy, Raymond Pfister, Sebastien Colombier, Francesco Patella, Salah Dine Qanadli, Matthias Kirsch
Summary: This study reviewed patients who underwent surgery for TAAD and found that 87.7% of patients experienced acute Type A aortic dissection (TAAD) at an aortic diameter below 45mm. The current aortic diameter threshold of 55mm excludes around 99% of TAAD patients from prophylactic ascending aorta replacement. The study suggests a need to reconsider the maximum diameter of the ascending aorta as part of a personalized decision-making process for preventive aorta replacement.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2021)
Review
Endocrinology & Metabolism
Everardo Josue Diaz-Lopez, Rocio Villar-Taibo, Gemma Rodriguez-Carnero, Antia Fernandez-Pombo, Roberto Garcia-Peino, Manuel Narciso Blanco-Freire, Alberto Pena-Dubra, Teresa Prado-Morana, Irea- Fernandez-Xove, Edurne Perez-Beliz, Jose Manuel Cameselle-Teijeiro, Alvaro Hermida-Ameijeiras, Miguel Angel Martinez-Olmos
Summary: This article reviews the rare presentation of hypokalaemic rhabdomyolysis as a result of primary aldosteronism (PA). A systematic review of the literature identified 37 cases of hypokalaemic rhabdomyolysis due to PA. It highlights the importance of suspecting PA when severe hypokalaemia and hypertension are present.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Domenico Spinelli, Fred A. Weaver, Ali Azizzadeh, Gregory A. Magee, Gabriele Piffaretti, Filippo Benedetto, Charles C. Miller, Harleen K. Sandhu, Dennis R. Gable, Santi Trimarchi
Summary: The study aimed to analyze the outcomes of thoracic endovascular aortic repair for complicated and uncomplicated acute type B aortic dissections. The data from WL Gore's Global Registry for Endovascular Aortic Treatment showed that the 30-day mortality and perioperative complications were equally low for both complicated and uncomplicated type B aortic dissections, and the midterm outcome was positive.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Surgery
Daniele Bissacco, Chiara Malloggi, Chiara Lomazzi, Maurizio Domanin, Andrea Odero, Santi Trimarchi, Renato Casana
Summary: This study aims to investigate the role of quality of life assessment in patients treated with RFA of the great saphenous vein and phlebectomies, and compare the differences between recanalized and non-recanalized patients.
Article
Radiology, Nuclear Medicine & Medical Imaging
Aldo Paolucci, Anna Maria Ierardi, Sophia Hohenstatt, Viviana Grassi, Silvia Romagnoli, Lorenzo Pignataro, Santi Trimarchi, Gianpaolo Carrafiello
Summary: In this study, the authors reported the first experience of direct percutaneous puncture technique using the low-viscosity formula of SQUID-12 for pre-operative embolization of carotid body paragangliomas. The additional use of a transitory balloon-blockage at the origin of the external carotid artery aims to provide higher protection and reduce the risk of non-target embolization and subsequent neurological sequelae. The results showed that this technique is safe and efficient with few complications.
Article
Peripheral Vascular Disease
Daniele Bissacco, Chiara Malloggi, Maurizio Domanin, Chiara Lomazzi, Valerio Tolva, Andrea Odero, Santi Trimarchi, Renato Casana
Summary: The study found that the recanalization rates of GSV at 1 week, 1, 3, and 5 years were 2.4%, 4.3%, 9.3%, and 17.5% respectively. Factors such as CEAP classification C4 and 5, preoperative GSV diameter >6 mm, and smoking history were independent predictors of recanalization. Age >61 years and postoperative complications like pigmentation, edema, and paresthesia were dependent risk factors.
Article
Cardiac & Cardiovascular Systems
Arnoud V. Kamman, Pieter A. J. van Bakel, Bo Yang, David M. Williams, Karen M. Kim, Minhaj S. Khaja, Frans L. Moll, Joost A. van Herwaarden, Santi Trimarchi, Kim A. Eagle, Jonathan L. Eliason, Himanshu J. Patel
SEMINARS IN THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Engineering, Biomedical
Daniele Bianchi, Michele Conti, Daniele Bissacco, Maurizio Domanin, Santi Trimarchi, Ferdinando Auricchio
Summary: This study aims to elucidate the biomechanical mechanisms of TEVAR by combining ex vivo and in silico analysis. The results show an increase in pulse wave velocity after TEVAR, and the numerical analysis demonstrates that oversized stent-grafts lead to an increase in local stress.
INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING
(2023)
Article
Cardiac & Cardiovascular Systems
Michele Di Mauro, Giorgia Bonalumi, Ilaria Giambuzzi, Guglielmo Mario Actis Dato, Paolo Centofanti, Alessandro Della Corte, Ester Della Ratta, Diego Cugola, Maurizio Merlo, Francesco Santini, Antonio Salsano, Mauro Rinaldi, Samuel Mancuso, Giangiuseppe Cappabianca, Cesare Beghi, Carlo De Vincentiis, Andrea Biondi, Ugolino Livi, Sandro Sponga, Davide Pacini, Giacomo Murana, Roberto Scrofani, Carlo Antona, Giovanni Cagnoni, Francesco Nicolini, Filippo Benassi, Michele De Bonis, Alberto Pozzoli, Marco Pano, Salvatore Nicolardi, Giosue Falcetta, Andrea Colli, Francesco Musumeci, Riccardo Gherli, Enrico Vizzardi, Loris Salvador, Marco Piciche, Domenico Paparella, Vito Margari, Giovanni Troise, Emmanuel Villa, Yudit Dossena, Carla Lucarelli, Francesco Onorati, Giuseppe Faggian, Giovanni Mariscalco, Daniele Maselli, Fabio Barili, Alessandro Parolari, Roberto Lorusso
Summary: This study aims to compare the early and late mortality of acute isolated tricuspid valve infective endocarditis (TVIE) treated with valve repair or replacement. The results indicate that TV repair has a lower mortality and major complication rate compared with TV replacement, but statistical significance was not reached. Long-term follow-up shows that regardless of the type of surgery used to treat TVIE, the patients have excellent survival and low recurrence rate of IE.
JOURNAL OF CARDIOVASCULAR MEDICINE
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Gabriele Piffaretti, Tim J. Mandigers, Robin H. Heijmen, Santi Trimarchi
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Tim J. Mandigers, Santi Trimarchi, Gabriele Piffaretti
JOURNAL OF CARDIAC SURGERY
(2022)
Article
Biophysics
Anna Ramella, Francesco Migliavacca, Tim J. Mandigers, Daniele Bissacco, Maurizio Domanin, Santi Trimarchi, Giulia Luraghi
Summary: Thoracic Endovascular Aortic Repair (TEVAR) is a minimally invasive technique for treating thoracic aorta pathologies. Computational models, such as finite element analysis, can be used to predict clinical procedure outcomes or conduct in-silico clinical trials. This study applies a validated TEVAR methodology to a patient-specific case and assesses the overall applicability of the TEVAR modeling using the ASME V&V40 protocol. Validation evidence sources are identified and adopted to demonstrate the reliability and applicability of the numerical procedure.
JOURNAL OF BIOMECHANICS
(2023)
Article
Surgery
Mario D'Oria, Santi Trimarchi, Chiara Lomazzi, Gilbert R. Upchurch Jr, Velipekka Suominen, Daniele Bissacco, Jacopo Taglialavoro, Sandro Lepidi
Summary: This study aimed to identify the factors associated with in-hospital serious adverse events in older patients undergoing elective endovascular aortic repair. The analysis of data from older patients aged 75 and above who underwent the procedure revealed that the occurrence of in-hospital complications was related to age, history of chronic obstructive pulmonary disease, and prior requirement for dialysis.
Article
Medicine, General & Internal
Francesco Secchi, Davide Capra, Caterina Beatrice Monti, Nazanin Mobini, Maria Del Mar Galimberti Ortiz, Santi Trimarchi, Daniela Mazzaccaro, Paolo Righini, Giovanni Nano, Francesco Sardanelli
Summary: This study aimed to investigate the use of unenhanced magnetic resonance imaging (MRI) as a safe and highly sensitive tool for endoleak screening in patients treated with endovascular aneurysm repair (EVAR). The study found that unenhanced MRI has perfect sensitivity for endoleak detection, but subpar specificity.
Review
Surgery
Gianmarco Zuccon, Mario D'Oria, Frederico Bastos Goncalves, Carlota Fernandez-Prendes, Kevin Mani, Daniel Caldeira, Mark Koelemay, Daniele Bissacco, Santi Trimarchi, Isabelle Van Herzeele, Anders Wanhainen
Summary: This scoping review assessed the rate and risk factors of type Ib endoleak in patients undergoing endovascular aneurysm repair (EVAR) for abdominal aortic aneurysm (AAA), and evaluated the evidence linking type Ib endoleak to short and long term outcomes. The study found that the frequency of type Ib endoleak ranged from 0% to 8%, and it was associated with certain anatomical features. In some cases, type Ib endoleak can be corrected by endovascular means.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Maurizio Domanin, Lorenzo Bennati, Christian Vergara, Daniele Bissacco, Chiara Malloggi, Vincenzo Silani, Gianfranco Parati, Santi Trimarchi, Renato Casana
Summary: In asymptomatic carotid stenosis (ACS), different plaque types, i.e. lipidic (LP), fibrous (FP), and calcific (CP), could have different hemodynamic and structural behaviors.
JOURNAL OF CARDIOVASCULAR SURGERY
(2023)
Article
Health Care Sciences & Services
Eugenio Martelli, Matilde Zamboni, Giovanni Sotgiu, Laura Saderi, Massimo Federici, Giuseppe M. Sangiorgi, Mariangela V. Puci, Allegra R. Martelli, Teresa Messina, Paolo Frigatti, Maria Pia Borrelli, Carlo Ruotolo, Ilaria Ficarelli, Paolo Rubino, Francesco Pezzo, Luciano Carbonari, Andrea Angelini, Edoardo Galeazzi, Luca Calia Di Pinto, Franco M. Fiore, Armando Palmieri, Giorgio Ventoruzzo, Giulia Mazzitelli, Franco Ragni, Antonio Bozzani, Enzo Forliti, Claudio Castagno, Pietro Volpe, Mafalda Massara, Diego Moniaci, Elisa Pagliasso, Tania Peretti, Mauro Ferrari, Nicola Troisi, Piero Modugno, Maurizio Maiorano, Umberto M. Bracale, Marco Panagrosso, Mario Monaco, Giovanni Giordano, Giuseppe Natalicchio, Antonella Biello, Giovanni M. Celoria, Alessio Amico, Mauro Di Bartolo, Massimiliano Martelli, Roberta Munao, Davide Razzano, Giovanni Colacchio, Francesco Bussetti, Gaetano Lanza, Antonio Cardini, Bartolomeo Di Benedetto, Mario De Laurentis, Maurizio Taurino, Pasqualino Sirignano, Pierluigi Cappiello, Andrea Esposito, Santi Trimarchi, Silvia Romagnoli, Andrea Padricelli, Giorgio Giudice, Adolfo Crinisio, Giovanni Di Nardo, Giuseppe Battaglia, Rosario Tringale, Salvatore De Vivo, Rita Compagna, Valerio S. Tolva, Ilenia D'Alessio, Ruggiero Curci, Simona Giovannetti, Giuseppe D'Arrigo, Giusi Basile, Dalmazio Frigerio, Gian Franco Veraldi, Luca Mezzetto, Arnaldo Ippoliti, Fabio M. Oddi, Alberto M. Settembrini
Summary: This is a study on the sex-related differences in 30-day/1-year mortality in patients with chronic limb-threatening ischemia (CLTI). The results showed that women had a higher proportion of CLTI cases above the age of 75, while men had a higher proportion of smokers, dialysis patients, and comorbidities such as diabetes. There was no difference in mortality statistics between the sexes.
JOURNAL OF PERSONALIZED MEDICINE
(2023)