Chelating behavior, thermal studies and biocidal efficiency of tioconazole and its complexes with some transition metal ions

New seven metal complexes of tioconazole drug with the general formulae [MCl2(L)(2)(H2O)(x)].yH(2)O (where, x = 0 and y = 1 for M = Mn(II) or x = 2, y = 2 for M = Co(II)), and x = 0, y = 3 for M = Cu(II), Ni(II), Zn(II)) and [MCl2(L)(2)(H2O)(2)]Cl.3H(2)O (where M = Cr(III) and Fe(III)) have been prepared and characterized based on elemental analyses, IR, magnetic moment, molar conductance, and thermal analyses techniques. From molar conductance data bivalent metal chelates are non-electrolytes while Cr(III) and Fe(III) chelates are electrolytes and of 1:1 type. According to the IR spectral data, TCNZ is coordinated to the metal ions in a neutral unidentate manner with N donor site of the imidazole-N. All the complexes are octahedral except Mn(II) complex has tetrahedral structure. TCNZ drug and its metal complexes were also screened for their biological activity.