Journal
JOURNAL OF THEORETICAL BIOLOGY
Volume 292, Issue -, Pages 86-92Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jtbi.2011.09.032
Keywords
Bone modelling; Piezoelectricity; Finite element modelling; Mechanosensor mechanism; Mechano-electrical modelling
Categories
Funding
- Spanish Ministry of Science and Technology [DPI2009-14115-C03-01, MTM2006-13981]
- FPI
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We have developed a mathematical approach for modelling the piezoelectric behaviour of bone tissue in order to evaluate the electrical surface charges in bone under different mechanical conditions. This model is able to explain how bones change their curvature, where osteoblasts or osteoclasts could detect in the periosteal/endosteal surfaces the different electrical charges promoting bone formation or resorption. This mechanism also allows to understand the BMU progression in function of the electromechanical bone behaviour. (C) 2011 Elsevier Ltd. All rights reserved.
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