Review
Plant Sciences
Alfonsina Milito, Moritz Aschern, Josie L. McQuillan, Jae-Seong Yang
Summary: This review focuses on Chlamydomonas reinhardtii, a microalgal species commonly used in bioengineering research, and discusses the key obstacles and potential solutions in synthetic promoter development. Microalgae have great potential as carbon-fixing biofactories to provide safe and sustainable high-value compounds, but optimizing their metabolic outputs and making them competitive with established industrial hosts requires precise control over transgene expression. However, the current repertoire of functional synthetic promoters for microalgae, especially for C. reinhardtii, is limited compared to other commercial chassis. The review highlights the need to expand the microalgal gene expression toolbox and proposes novel approaches and perspectives for synthetic promoter development in microalgae.
JOURNAL OF EXPERIMENTAL BOTANY
(2023)
Article
Materials Science, Multidisciplinary
Yang Yang, Yuqing Ren, Wei Song, Bohong Yu, Hongzhuo Liu
Summary: Hydrogels are widely used in the biomedical field, but selecting appropriate functional materials and design strategies for optimizing their biological performance remains challenging. This review outlines the principles of hydrogel system functionality, explores the relationship between basic properties of hydrogels and biological functions, and discusses the prospects of advanced applications. The principles and understanding presented in this article will facilitate the improvement of therapeutic performance and the development of functional biomaterials.
MATERIALS & DESIGN
(2022)
Article
Chemistry, Multidisciplinary
Yu-An Xiong, Zhu-Xiao Gu, Xian-Jiang Song, Jie Yao, Qiang Pan, Zi-Jie Feng, Guo-Wei Du, Hao-Ran Ji, Tai-Ting Sha, Ren-Gen Xiong, Yu-Meng You
Summary: CDWs are a special microstructure in molecular ferroelectric materials that greatly improve conductivity, piezoelectricity, and photovoltaic efficiency. This study successfully achieved charge diffusion of CDWs at variable temperatures in molecular ferroelectrics for the first time, providing a new design strategy for n-type molecular ferroelectrics and shedding light on their applications in flexible electronics and microsensors.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Physical
Daniela Millan, Cristian Malebran, Rodrigo Ormazabal-Toledo
Summary: In this study, a task-specific medium for ultrasound extraction of polyphenols from Luma apiculata was designed and analyzed using experimental and theoretical methods. The results indicate that choline chloride-based deep eutectic solvents (DESs) are suitable for this extraction. Molecular dynamics simulations revealed that an adequate DES should contain organic acids, amines or quaternary ammonium salts, an appropriate amount of water for eutectic mixture formation, and acidic anions. The synergetic solvation of polyphenols by each component was found to be crucial for their extraction efficiency.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Multidisciplinary
G. George, O. A. Stasyuk, M. Sola, A. J. Stasyuk
Summary: Belt-shaped aromatic compounds are among the most attractive classes of radial pi-conjugated nanocarbon molecules. We propose rules for their design with improved electron-donating properties.
Article
Multidisciplinary Sciences
Lorenzo Olivi, Mareike Berger, Ramon N. P. Creyghton, Nicola De Franceschi, Cees Dekker, Bela M. Mulder, Nico J. Claassens, Pieter Rein ten Wolde, John van der Oost
Summary: Recent developments in synthetic biology may bring the generation of a synthetic cell within reach, with a key feature being a functional cell cycle. While progress has been made in establishing individual machineries, integrating and controlling them in a synthetic cell cycle is still a challenge to be addressed. This Perspective discusses potential paths towards achieving an integrated synthetic cell cycle.
NATURE COMMUNICATIONS
(2021)
Review
Chemistry, Inorganic & Nuclear
Hiroaki Tada
Summary: This article provides an overview of the fundamentals and recent progress of Au NP-based HET-type plasmonic photocatalysts for OER. It discusses the rational design and concrete design of plasmonic photocatalysts, as well as recent advanced studies on plasmonic photocatalysts for OER. The article concludes with a direction for future research on plasmonic photocatalysts.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Inorganic & Nuclear
Xing Liu, Hui Li, Ting Zhang, Lei Zhang, Ming Li, Rongxing He
Summary: A zero-dimensional (0D) (H5O2)(C4H14N2S2)(2)BiCl8: Sb3+ single crystal is obtained by the cooling crystallization method, which shows reversible photoluminescence (PL) upon H5O2+Cl- removal and insertion. The significant distortion of [SbCl6](3-) octahedron induced by guest (H5O2+Cl-) removal at the ground state, especially at the excited state, is responsible for the disparate PL performance. Moreover, (C4H14N2S2)(2)BiCl7: Sb3+ exhibits a fast response (<3 s) to dilute hydrochloric acid with naked-eye perceivable PL color changes, making it a potential sensing material for hydrochloric acid.
INORGANIC CHEMISTRY
(2023)
Editorial Material
Chemistry, Multidisciplinary
Ivan Huc, Sunbum Kwon, Hee-Seung Lee
Summary: The Special Collection "Fruitful Foldamers" is curated by guest editors Ivan Huc, Sunbum Kwon, and Hee-Seung Lee, featuring top-quality multidisciplinary research and review articles on the synthesis, properties, and applications of foldamers, including design, self-assembly, guest recognition, catalytic activity, optical, and biological properties.
Review
Chemistry, Inorganic & Nuclear
Cunfa Sun, Boon K. Teo, Chenglong Deng, Jinqing Lin, Geng-Geng Luo, Chen-Ho Tung, Di Sun
Summary: This paper summarizes the catalytic properties, fundamental concepts, particle growth processes, and catalytic processes of hydrido-coinage-metal clusters at the atomic level. Isolation and characterization of these atomically precise hydrido-coinage-metal nanoclusters are essential for better understanding of their structure-property correlations.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Biotechnology & Applied Microbiology
Viktor Haellman, Pratik Saxena, Yanrui Jiang, Martin Fussenegger
Summary: This study presents a framework for implementing synthetic gene switches in PSCs by combining different elements. By multiplexing the VanA and rtTA systems, independent control of the expression of different transcription factors in human induced PSCs was achieved to enhance lineage specification towards early pancreatic progenitors.
METABOLIC ENGINEERING
(2021)
Review
Chemistry, Multidisciplinary
Hongzhu Jiang, Zheng Chen, Yuanyuan Yang, Cheng Fan, Jingwen Zhao, Guanglei Cui
Summary: This review discusses the challenges, progress, and future research directions of electrolytes for dual-ion batteries (DIBs). The composition of electrolytes has a significant impact on battery performance, making the study of electrolyte properties crucial.
Article
Chemistry, Multidisciplinary
Anirban Das, Anju Yadav, Mona Gupta, R. Purushotham, Vishram L. Terse, Vicky Vishvakarma, Sameer Singh, Tathagata Nandi, Arkadeep Banerjee, Kalyaneswar Mandal, Shachi Gosavi, Ranabir Das, Sri Rama Koti Ainavarapu, Sudipta Maiti
Summary: By constructing a xenonucleus based on specific design principles, the refolding speed of ubiquitin protein can be increased. This method provides a new approach for constructing specific folding catalysts for proteins with well-defined folding nuclei.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Mathematics
Gradimir Milovanovic, Abdullah Mir
Summary: Various versions of Bernstein and Turan-type inequalities have been generalized for rational functions in the complex plane, inspired by classical inequalities. The results obtained in this study extend many inequalities for polynomials as special cases.
REVISTA DE LA REAL ACADEMIA DE CIENCIAS EXACTAS FISICAS Y NATURALES SERIE A-MATEMATICAS
(2021)
Article
Biochemical Research Methods
Marcio Gameiro, Tomas Gedeon, Shane Kepley, Konstantin Mischaikow
Summary: This research introduces a modeling and computational framework to efficiently screen thousands of potential network designs and create a database for constructing robust switches. Evaluating network capabilities for specific dynamic behaviors, it offers guidance for synthetic biologists to focus on experimental and modeling tools.
PLOS COMPUTATIONAL BIOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Jinny X. Zhang, John Z. Fang, Wei Duan, Lucia R. Wu, Angela W. Zhang, Neil Dalchau, Boyan Yordanov, Rasmus Petersen, Andrew Phillips, David Yu Zhang
Article
Nanoscience & Nanotechnology
Gourab Chatterjee, Neil Dalchau, Richard A. Muscat, Andrew Phillips, Georg Seelig
NATURE NANOTECHNOLOGY
(2017)
Article
Biochemical Research Methods
Luca Cardelli, Rosa D. Hernansaiz-Ballesteros, Neil Dalchau, Attila Csikasz-Nagy
PLOS COMPUTATIONAL BIOLOGY
(2017)
Article
Multidisciplinary Sciences
Stephen Smith, Neil Dalchau
JOURNAL OF THE ROYAL SOCIETY INTERFACE
(2018)
Article
Computer Science, Artificial Intelligence
Neil Dalchau, Gregory Szep, Rosa Hernansaiz-Ballesteros, Chris P. Barnes, Luca Cardelli, Andrew Phillips, Attila Csikasz-Nagy
Article
Computer Science, Artificial Intelligence
Neil Dalchau, Gregory Szep, Rosa Hernansaiz-Ballesteros, Chris P. Barnes, Luca Cardelli, Andrew Phillips, Attila Csikasz-Nagy
Article
Immunology
Denise S. M. Boulanger, Ruth C. Eccleston, Andrew Phillips, Peter Coveney, Tim Elliott, Neil Dalchau
FRONTIERS IN IMMUNOLOGY
(2018)
Article
Multidisciplinary Sciences
Niall Murphy, Rasmus Petersen, Andrew Phillips, Boyan Yordanov, Neil Dalchau
JOURNAL OF THE ROYAL SOCIETY INTERFACE
(2018)
Article
Computer Science, Artificial Intelligence
Yiyu Xiang, Neil Dalchau, Baojun Wang
Article
Nanoscience & Nanotechnology
Alex Joesaar, Shuo Yang, Bas Bogels, Ardjan van der Linden, Pascal Pieters, B. V. V. S. Pavan Kumar, Neil Dalchau, Andrew Phillips, Stephen Mann, Tom F. A. de Greef
NATURE NANOTECHNOLOGY
(2019)
Article
Multidisciplinary Sciences
Eugene Nadezhdin, Niall Murphy, Neil Dalchau, Andrew Phillips, James C. W. Locke
NATURE COMMUNICATIONS
(2020)
Article
Biology
Andrew L. Krause, Vaclav Klika, Jacob Halatek, Paul K. Grant, Thomas E. Woolley, Neil Dalchau, Eamonn A. Gaffney
BULLETIN OF MATHEMATICAL BIOLOGY
(2020)
Article
Multidisciplinary Sciences
Trevor Y. H. Ho, Alexander Shao, Zeyu Lu, Harri Savilahti, Filippo Menolascina, Lei Wang, Neil Dalchau, Baojun Wang
Summary: Split inteins are powerful tools for designing synthetic split proteins. Here the authors use a mini-Mu transposon screen to map split sites, enabling the development of protein-based logic gates and fine control of protein activity.
NATURE COMMUNICATIONS
(2021)
Article
Multidisciplinary Sciences
Jinny X. Zhang, Boyan Yordanov, Alexander Gaunt, Michael X. Wang, Peng Dai, Yuan-Jyue Chen, Kerou Zhang, John Z. Fang, Neil Dalchau, Jiaming Li, Andrew Phillips, David Yu Zhang
Summary: A deep learning model is developed to predict NGS depth using DNA probe sequences, applied to both human and non-human sequencing panels. The model shows high accuracy in cross-validation for different panels.
NATURE COMMUNICATIONS
(2021)
Article
Multidisciplinary Sciences
Paul K. Grant, Gregory Szep, Om Patange, Jacob Halatek, Valerie Coppard, Attila Csikasz-Nagy, Jim Haseloff, James C. W. Locke, Neil Dalchau, Andrew Phillips
NATURE COMMUNICATIONS
(2020)