Article
Medicine, General & Internal
Ipos Ngay Lukusa, Nick Van Reet, Dieudonne Mumba Ngoyi, Erick Mwamba Miaka, Justin Masumu, Pati Patient Pyana, Wilfried Mutombo, Digas Ngolo, Vincent Kobo, Felix Akwaso, Medard Ilunga, Lewis Kaninda, Sylvain Mutanda, Dieudonne Mpoyi Muamba, Olaf Valverde Mordt, Antoine Tarral, Sandra Rembry, Philippe Buscher, Veerle Lejone
Summary: The detection of spliced leader (SL)-RNA shows high specificity and sensitivity in the assessment of treatment outcomes for gambiense human African trypanosomiasis (HAT), allowing the detection of relapses without the need for lumbar puncture.
Article
Clinical Neurology
Ingo Fietze, Naima Laharnar, Panagiotis Bargiotas, Ozen K. Basoglu, Zoran Dogas, Marta Drummond, Francesco Fanfulla, Thorarinn Gislason, Haralampos Gouveris, Ludger Grote, Holger Hein, Poul Jennum, Pavol Joppa, Klaas van Kralingen, John Arthur Kvamme, Carolina Lombardi, Ondrej Ludka, Wolfgang Mallin, Oreste Marrone, Walter T. McNicholas, Stefan Mihaicuta, Josep Montserrat, Giora Pillar, Athanasia Pataka, Winfried Randerath, Renata L. Riha, Gabriel Roisman, Tarja Saaresranta, Sophia E. Schiza, Pawel Sliwinski, Juris Svaza, Paschalis Steiropoulos, Renauld Tamisier, Dries Testelmans, Georgia Trakada, Johan Verbraecken, Rolandas Zablockis, Thomas Penzel
Summary: This study conducted a questionnaire survey on European Sleep Centers and found that in the past decade, there have been improvements in the qualifications of sleep center personnel, a shift towards more automated approaches in OSA diagnosis and treatment procedures, and a more prominent use of telemedicine.
Article
Automation & Control Systems
Lingxiang Zheng, Han Wu, Lin Yang, Yonghua Lao, Qinyong Lin, Rongqian Yang
Summary: The study introduces a respiratory follow-up robotic system to improve accuracy and safety in thoracic-abdominal puncture surgery. By analyzing breathing motion in real-time, the system compensates for tissue deformation during puncture procedures, achieving outstanding experimental results.
IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS
(2021)
Article
Clinical Neurology
Nea Kalleinen, Jenni Aittokallio, Laura Lampio, Matti Kaisti, Paivi Polo-Kantola, Olli Polo, Olli J. Heinonen, Tarja Saaresranta
Summary: This 10-year observational study found that changes in sleep architecture in middle-aged women were more age-dependent rather than menopause-dependent. With aging, shorter sleep latency, decreased stage 2 sleep, and increased slow-wave sleep were observed.
Review
Medicine, General & Internal
Andres Alvarez-Rodriguez, Bo-Kyung Jin, Magdalena Radwanska, Stefan Magez
Summary: Human African Trypanosomiasis (HAT) is a disease caused by parasites of the genus Trypanosoma brucei. Different subspecies cause different infections. Diagnosing and treating HAT has improved, but further research and improvements are needed.
FRONTIERS IN MEDICINE
(2022)
Article
Medicine, General & Internal
Xiang Li, Jinzhu Bai, Yi Hong, Junwei Zhang, Hehu Tang, Zhen Lyu, Shujia Liu, Shizheng Chen, Jiesheng Liu
Summary: The study on long-term clinical outcomes of percutaneous endoscopic lumbar discectomy for lumbar degenerative disease showed favorable results, with limited discectomy preserving disc height well and minimizing the risk of residual back pain. The study concluded that postoperative dysesthesia is a common complication initially, but PELD using the transforaminal approach can provide good results in the long-term follow-up period.
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
(2021)
Article
Medicine, General & Internal
Takahiro Igari, Koji Otani, Miho Sekiguchi, Shin-ichi Konno
Summary: Lumbar spinal stenosis (LSS) is a significant health issue in aging societies, as it can greatly impact quality of life and daily activities. This study aimed to examine the 10-year progression of LSS symptoms in a community population of over 1000 individuals through prospective data collection. The findings revealed that the presence of LSS symptoms at the initial survey was a strong predictor of symptoms after 10 years. However, 60% of individuals who initially presented with LSS symptoms did not continue to show symptoms at the 10-year follow-up, consistent with the 1-year and 6-year findings.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Robert Siegel, Ricardo Niklas Werner, Stephan Koswig, Matthew Gaskins, Claus Roedel, Felix Aigner
Summary: The study provides detailed information on the development of the guidelines for the treatment of anal cancer. It recommends chemoradiotherapy as the standard treatment for stages II-III, with a suggestion against biopsy in complete clinical response. For stage IV anal cancer, there are only open recommendations, urging further research in this area.
DEUTSCHES ARZTEBLATT INTERNATIONAL
(2021)
Article
Medicine, General & Internal
Anna Zoellner, Klaus Herfarth, Michael Herold, Wolfram Klapper, Nicole Skoetz, Wolfgang Hiddemann
Summary: Follicular lymphoma primarily affects elderly individuals, with treatment options including radiotherapy, chemotherapy, or maintenance therapy depending on the severity of the disease. Thorough follow-up is necessary to detect late complications such as second malignancies or organ damage.
DEUTSCHES ARZTEBLATT INTERNATIONAL
(2021)
Review
Rheumatology
Fiona L. Coath, Chetan Mukhtyar
Summary: The study shows that Colour Doppler ultrasonography is an effective tool for objective assessment of giant cell arteritis, with good reliability and validity in determining ultrasonographic changes. Although not well-defined in follow-up, it has potential value in diagnosis.
Review
Medicine, General & Internal
Clara Carnicer-Caceres, Jose Antonio Arranz-Amo, Cristina Cea-Arestin, Maria Camprodon-Gomez, David Moreno-Martinez, Sara Lucas-Del-Pozo, Marc Molto-Abad, Ariadna Tigri-Santina, Irene Agraz-Pamplona, Jose F. Rodriguez-Palomares, Jorge Hernandez-Vara, Mar Armengol-Bellapart, Mireia del-Toro-Riera, Guillem Pintos-Morell
Summary: Fabry disease is a lysosomal storage disorder caused by mutations in the GLA gene, leading to gradual accumulation of globotriaosylceramide in different tissues, which can induce multiorgan lesions, especially in the kidney, heart, and nervous system. Enzyme replacement therapy can delay disease progression, but early diagnosis remains a clinical challenge, prompting the search for biomarkers to detect and predict disease evolution.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Oncology
Novella Pugliese, Marco Picardi, Roberta Della Pepa, Claudia Giordano, Francesco Muriano, Aldo Leone, Giuseppe Delle Cave, Alessandro D'Ambrosio, Violetta Marafioti, Maria Gabriella Rascato, Daniela Russo, Massimo Mascolo, Fabrizio Pane
Summary: This study focused on the management and treatment strategies of NLPHL based on risk stratification, confirming the benefit of Rituximab, particularly for advanced-stage patients. Larger cohort studies are needed for further validation.
Article
Medicine, General & Internal
Do Yeon Rhee, Yong Ahn
Summary: This study demonstrates the specific technique and clinical outcomes of full-endoscopic lumbar foraminotomy (FELF) for foraminal stenosis in patients with stable spondylolisthesis. Twenty-three patients were treated with FELF and followed up for 2 years. The results showed significant improvement in visual analog pain score (VAS) and Oswestry Disability Index (ODI) at the two-year follow-up, with a success rate of 90.5%. No significant surgical complications or signs of further instability were observed.
Article
Oncology
Xiaojuan Guo, Ling Gao, Jie Liu, Wenhui Lu, Jin Wang, Qiumin Qu
Summary: This study aimed to investigate the public acceptability of lumbar puncture in the diagnosis of Alzheimer's disease and identify the factors influencing patient decision. A questionnaire was administered to participants native to Xi'an using the Sojump application. The results showed that over 80% of the public had a positive attitude towards lumbar puncture for the diagnosis of Alzheimer's disease, but this attitude was influenced by factors such as age, education level, economic status, and type of occupation.
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2023)
Article
Surgery
Jin Tang, Ying Li, Congjun Wu, Wei Xie, Xugui Li, Xuewen Gan, Qilin Lu
Summary: This study retrospectively analyzed the mid-term clinical efficacy of TELD for single-level LDD and its effect on intervertebral disc degeneration with a minimum of 6-year follow-up.
FRONTIERS IN SURGERY
(2022)
Article
Clinical Neurology
Raymond Cespuglio
Article
Infectious Diseases
M. Desnos-Ollivier, S. Bretagne, A. Boullie, C. Gautier, F. Dromer, O. Lortholary, N. Brieu, T. Chouaki, M. Pihet, S. Bland, V. Blanc, A. P. Bellanger, F. Grenouillet, L. Millon, S. Brun, I. Poilane, F. Gabriel, A. L. Roux, D. Quinio, E. Moalic, J. Bonhomme, P. Poirier, C. Nourrisson, F. Botterel, N. Ait-Ammar, N. Fauchet, E. Forget, F. Dalle, P. Cahen, C. Lawrence, O. Faure, D. Maubon, M. Cornet, M. Nicolas, M. Demar, C. Nabet, A. Angoulvant, S. Picot, N. Traversier, O. Eloy, B. Sendid, B. Bouteille, F. Persat, M. Wallon, S. Ranque, H. Piarroux, N. Desbois, L. Collet, N. Bourgeois, F. Moriot, O. Mouquet, L. Hasseine, M. Gari-Toussaint, M. Sasso, D. Poisson, A. Minoza, C. Kauffman, D. Toubas, J. P. Gangneux, L. Favennec, N. Godineau, H. Raberin, V. Bru, S. Cassaing, E. Bailly, E. Chachaty, C. Bonnal, A. Paugam, B. Heym, M-E. Bougnoux, E. Sitterle, A. Alanio, D. Moissenet, S. Bonacorsi, P. Mariani
CLINICAL MICROBIOLOGY AND INFECTION
(2019)
Article
Infectious Diseases
M. Salse, J. -P. Gangneux, S. Cassaing, L. Delhaes, A. Fekkar, D. Dupont, F. Botterel, D. Costa, N. Bourgeois, B. Bouteille, S. Houze, E. Dannaoui, H. Guegan, E. Charpentier, F. Persat, L. Favennec, L. Lachaud, M. Sasso
CLINICAL MICROBIOLOGY AND INFECTION
(2019)
Article
Multidisciplinary Sciences
Raymond Cespuglio, Donia Amrouni, Elizabeth Raymond, Bernard Bouteille, Alain Buguet
Review
Clinical Neurology
A. Buguet, R. Gati Ouonkoye, P. Bogui, R. Cespuglio
REVUE NEUROLOGIQUE
(2019)
Article
Behavioral Sciences
Joao Pedro Costa-Nunes, Anna Gorlova, Dmitrii Paylov, Raymond Cespuglio, Anna Gorovaya, Andrei Proshin, Aleksei Umriukhin, Eugene D. Ponomarev, Alan Kalueff, Tatyana Strekalova, Careen A. Schroeter
STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS
(2020)
Article
Neurosciences
Ekaterina Veniaminova, Raymond Cespuglio, Irina Chernukha, Angelika G. Schmitt-Boehrer, Sergey Morozov, Allan V. Kalueff, Oxana Kuznetsova, Daniel C. Anthony, Klaus-Peter Lesch, Tatyana Strekalova
FRONTIERS IN NEUROSCIENCE
(2020)
Article
Mycology
A-P Bellanger, F. Persat, F. Foulet, C. Bonnal, I Accoceberry, C. Angebault, A. Angoulvant, O. Augereau, E. Bailly, F. Bert, J. Bonhomme, J-P Bouchara, M-E Bougnoux, P. Bourdeau, B. Bouteille, S. Brun, K. Brunet, A-M Camin-Ravenne, S. Cassaing, T. Chouaki, M. Cornet, D. Costa, N. Desbois, J. Dorin, A. Fekkar, A. Fiacre, E. Frealle, J-P Gangneux, J. Guillot, J. Guitard, L. Hasseine, A. Huguenin, L. Lachaud, S. Larreche, R-A Lavergne, S. Le Gal, Y. Le Govic, V Letscher-Bru, M. Machouart, E. Mazars, C. Nourrisson, A. Paugam, S. Ranque, V Risco-Castillo, M. Sasso, M. Sautour, B. Sendid, Y. Senghor, F. Botterel, Eric Dannaoui
JOURNAL DE MYCOLOGIE MEDICALE
(2020)
Article
Dermatology
Marie Desnos-Ollivier, Corinne Maufrais, Marc Pihet, Christine Aznar, Francoise Dromer
Article
Infectious Diseases
Didier Bronnimann, Dea Garcia-Hermoso, Francoise Dromer, Fanny Lanternier
Summary: The study found that different species of Scedosporium fungi lead to distinct clinical presentations and outcomes. Infections caused by S. apiospermum were associated with malignancies and cutaneous involvement, while S. boydii infections were more related to solid organ transplantation, cerebral infections, fungemia, and early death. Additionally, infections caused by L. prolificans exhibited a different clinical pattern, with more neutropenic patients, breakthrough infections, fungemia, and disseminated infections.
Letter
Clinical Neurology
Raymond Cespuglio, Tatyana Strekalova, Peter S. Spencer, Gustavo C. Roman, Jacques Reis, Bernard Bouteille, Alain Buguet
Article
Microbiology
A. Espinel-Ingroff, M. Sasso, J. Turnidge, M. Arendrup, F. Botterel, N. Bourgeois, B. Bouteille, E. Canton, S. Cassaing, E. Dannaoui, M. Dehais, L. Delhaes, D. Dupont, A. Fekkar, J. Fuller, G. Garcia-Effron, J. Garcia, G. M. Gonzalez, N. P. Govender, H. Guegan, J. Guinea, S. Houze, C. Lass-Florl, T. Pelaez, A. Forastiero, M. Lackner, R. Magobo
Summary: Susceptibility testing for antifungal drugs is crucial in the clinical setting, relying on categorical endpoints and epidemiological cutoff values for different species. Collaborative efforts have led to the development of Etest sensitivity values for various Candida and Aspergillus species, aiding in clinical laboratory testing.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2021)
Article
Microbiology
Stephane Bretagne, Karine Sitbon, Marie Desnos-Ollivier, Dea Garcia-Hermoso, Valerie Letscher-Bru, Sophie Cassaing, Laurence Millon, Florent Morio, Jean-Pierre Gangneux, Lilia Hasseine, Loic Favennec, Estelle Cateau, Eric Bailly, Maxime Moniot, Julie Bonhomme, Nicole Desbois-Nogard, Taieb Chouaki, Andre Paugam, Bernard Bouteille, Marc Pihet, Frederic Dalle, Odile Eloy, Milene Sasso, Magalie Demar, Patricia Mariani-Kurkdjian, Vincent Robert, Olivier Lortholary, Francoise Dromer
Summary: The epidemiology of invasive fungal diseases (IFDs) is difficult to determine due to diagnostic challenges. This study emphasizes the importance of active surveillance by mycologists and clinicians to understand global incidence and main IFDs. The findings show an increase in yeast fungemia and a higher prevalence of IFDs in older individuals. Despite advancements in diagnostic tools and antifungal drugs, global survival rates for IFDs have not improved.
Meeting Abstract
Biophysics
Julien Vaidie, Jean-Baptiste Woillard, Stephane Girault, Marie-Laure Darde, Arnaud Jaccard, Daniel Ajzenberg, Bernard Bouteille, Pascal Turlure
BONE MARROW TRANSPLANTATION
(2019)