Carnitine-Acyltransferase System Inhibition, Cancer Cell Death, and Prevention of Myc-Induced Lymphomagenesis

Mitochondrial Carnitine Palmitoyltransferase 1a (CPT1a) Is Part of an Outer Membrane Fatty Acid Transfer Complex

(2011) Kwangwon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Carnitine Palmitoyltransferase (CPT) Modulators: A Medicinal Chemistry Perspective on 35 Years of Research

(2011) Simona M. Ceccarelli et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Transcriptional Signature and Common Gene Networks Link Cancer with Lipid Metabolism and Diverse Human Diseases

(2010) Heather A. Hirsch et al.   CANCER CELL

Myc-dependent Mitochondrial Generation of Acetyl-CoA Contributes to Fatty Acid Biosynthesis and Histone Acetylation during Cell Cycle Entry

(2010) Fionnuala Morrish et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Cellular Metabolism by Protein Lysine Acetylation

(2010) S. Zhao et al.   SCIENCE

Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism☆

(2009) Divya Pathania et al.   ADVANCED DRUG DELIVERY REVIEWS

Mitochondria in the elderly: Is acetylcarnitine a rejuvenator?☆

(2009) Mariana G. Rosca et al.   ADVANCED DRUG DELIVERY REVIEWS

Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis

(2009) Daniel K. Nomura et al.   CELL

Structural insight into function and regulation of carnitine palmitoyltransferase

(2009) Arne C. Rufer et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

(2009) Ismael Samudio et al.   JOURNAL OF CLINICAL INVESTIGATION

LDH-A inhibition, a therapeutic strategy for treatment of hereditary leiomyomatosis and renal cell cancer

(2009) H. Xie et al.   MOLECULAR CANCER THERAPEUTICS

Regulatory enzymes of mitochondrial β-oxidation as targets for treatment of the metabolic syndrome

(2009) M. Schreurs et al.   Obesity Reviews

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

Glycolytic enzyme inhibitors in cancer treatment

(2008) Roberto Scatena et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Potentiation of chemotherapeutic drugs by energy metabolism inhibitors 2-deoxyglucose and etomoxir

(2008) Emma Hernlund et al.   INTERNATIONAL JOURNAL OF CANCER

Growth inhibition in antimycin A treated-lung cancer Calu-6 cells via inducing a G1 phase arrest and apoptosis

(2008) Yong Hwan Han et al.   LUNG CANCER

Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth

(2008) B. Clem et al.   MOLECULAR CANCER THERAPEUTICS

Methyl jasmonate binds to and detaches mitochondria-bound hexokinase

(2008) N Goldin et al.   ONCOGENE