Journal
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
Volume 9, Issue 5, Pages 799-803Publisher
SPRINGER
DOI: 10.1007/s13738-012-0080-9
Keywords
5-Substituted 1H-tetrazole; Nitrile; NaN3; Ammonium acetate; [3+2] Cycloaddition
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Funding
- DST
- UGC, New Delhi
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Synthesis of 5-substituted 1H-tetrazoles was achieved by [3+2] cycloaddition of nitriles and sodium azide in the presence of ammonium acetate. The reaction proceeds in situ formation of ammonium azide. Present protocol has advantage of good to excellent yields, short reaction times and simple isolation of products than reported methods.
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