Article
Medicine, General & Internal
Tsung-Tai Chen, Kuo-Inn Tsou, Waitim Jim, Chi-Nien Chen
Summary: The study found significant variation in risk-adjusted rates for NEC and IVH in premature birth care. Mortality rankings showed the lowest concordance between unadjusted and adjusted ranks. Risk adjustment is crucial for evaluating hospital performance, especially for mortality outcomes, as only a few of the risk-adjusted rates between outcomes were significantly correlated.
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
(2021)
Article
Gastroenterology & Hepatology
Alessandro Cucchetti, Luca Aldrighetti, Francesca Ratti, Alessandro Ferrero, Alfredo Guglielmi, Felice Giuliante, Umberto Cillo, Vincenzo Mazzaferro, Luciano De Carlis, Giorgio Ercolani
Summary: This study aimed to provide risk-adjusted outcome measures for laparoscopic liver resection (LLR) and analyze the heterogeneity among 41 participating hospitals. A risk-adjustment model was used to address confounding factors due to case-mix. The results showed that different hospitals operated on different types of patients, leading to heterogeneity in postoperative complications and prolonged in-hospital stay. Risk-adjustment accounted for this variability and yielded risk-standardized conversion rate, overall morbidity, major morbidity, and prolonged in-hospital stay.
JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
(2022)
Article
Economics
Darius N. Lakdawalla, Charles E. Phelps
Summary: The GRACE model introduces diminishing returns to QoL, reshaping conventional CEA practice in terms of WTP, treatment effectiveness adjustment, and the substitution rate between life expectancy and QoL based on health state. Implementing GRACE requires new parameters to describe risk preferences, the marginal rate of substitution, and treatment outcomes distributions.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2022)
Article
Mathematical & Computational Biology
Dan Jackson, Kirsty Rhodes, Mario Ouwens
Summary: The paper introduces the Matching-Adjusted Indirect Comparison (MAIC) method and extends it to achieve a larger effective sample size (ESS). It provides new analytical results explaining why the alternative method can lead to a larger ESS. Additionally, a new descriptive statistic is derived to quantify the difficulties in adjusting for specific covariates.
RESEARCH SYNTHESIS METHODS
(2021)
Article
Psychology, Multidisciplinary
Phillip M. Hughes, Megan S. Hughes
Summary: Research shows that being uninsured in the United States may increase the risk of developing depression. This association has important implications for health insurance policies and clinical mental health practice.
CURRENT PSYCHOLOGY
(2023)
Article
Health Care Sciences & Services
Jaime Barrio-Cortes, Maria Soria-Ruiz-Ogarrio, Maria Martinez-Cuevas, Almudena Castano-Reguillo, Mariana Bandeira-de Oliveira, Maria Teresa Beca-Martinez, Maria Carmen Lopez-Rodriguez, Maria Angeles Jaime-Siso
Summary: The study found that the characteristics and utilization of primary care (PC) and hospital care (HC) services by chronic patients varied according to their adjusted morbidity group (AMG) risk level. Although both levels of care had high utilization rates, primary care services were more commonly used than hospital care. Service utilization was associated with factors such as age, country of origin, immobility, high risk, and number and type of chronic diseases.
BMC HEALTH SERVICES RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
Abeer Alharbi
Summary: This study examined the willingness of Saudi Arabian people to pay for a National Health Insurance system. The results revealed that a majority of individuals were willing to contribute financially to the system, and this willingness was influenced by factors such as the type of healthcare provider used and satisfaction with current healthcare services. Age, region, and education were also found to be associated with the amount of money individuals were willing to pay.
Article
Clinical Neurology
James J. Sun, Bhathika Perera, William Henley, Heather Angus-Leppan, Indermeet Sawhney, Lance Watkins, Kiran N. Purandare, Mogbeyiteren Eyeoyibo, Mark Scheepers, Geraldine Lines, Robert Winterhalder, Samantha Ashby, Ravi De Silva, Jonjo Miller, David E. Philpott, Chris Ashwin, Joshua Howkins, Harriet Slater, David Medhurst, Rohit Shankar
Summary: A quarter of people with Intellectual Disability (ID) in the UK have epilepsy and their life expectancy is much shorter. Epilepsy in this population is often accompanied by polypharmacy and multi-morbidity. Epilepsy research on this population has been inadequate. This study examines the clinical and risk characteristics of a large cohort in England and Wales.
JOURNAL OF NEUROLOGY
(2022)
Article
Public, Environmental & Occupational Health
Katy Footman, Kratu Goel, Ulrika Rehnstrom Loi, Andrew J. Mirelman, Veloshnee Govender, Bela Ganatra
Summary: This study explores the inclusion of abortion services in health benefit packages globally. The findings reveal that less than half of the countries (45%) include abortion, but treatment for complications from unsafe abortion is more commonly included (63%). Abortion is less commonly included compared to other sexual and reproductive health services, and inclusion varies based on income and legal environment.
Article
Business, Finance
Michel Oskam, Richard C. C. van Kleef, Rene C. J. A. van Vliet
Summary: This study examines the improvement of the Dutch risk equalization model by redesigning the Diagnosis-based Cost Groups (DCGs). The results show that the redesigned DCGs can significantly reduce predictable profits and losses, and mitigate selection incentives.
INTERNATIONAL JOURNAL OF HEALTH ECONOMICS AND MANAGEMENT
(2023)
Article
Public, Environmental & Occupational Health
Jacob Bigio, Emma Hannay, Madhukar Pai, Bachti Alisjahbana, Rishav Das, Huy Ba Huynh, Uzma Khan, Lalaine Mortera, Thu Anh Nguyen, Muhammad Aamir Safdar, Suvesh Shrestha, A. Venkat Raman, Sharat Chandra Verma, Vijayashree Yellappa, Divya Srivastava
Summary: The Lancet Commission on Diagnostics highlighted the lack of access to diagnostic testing, especially at the primary care level, and emphasized the need for countries to include diagnostics in their universal health coverage benefits packages. We analyzed seven Asian low- and middle-income countries (LMICs) to understand the inclusion of diagnostics in their health benefit packages. We found heterogeneity among the countries and a lack of clear policy rationale and detailed information on the covered diagnostics.
Article
Public, Environmental & Occupational Health
Dinna Prapto Raharja, Retna Hanani, Fransiscus S. Joyoadisumarta, Nasreen S. Jessani, Inke Mathauer
Summary: This study examines how informal non-government patient navigation initiatives have emerged, are organized, and operate to enhance patient empowerment and JKN responsiveness in Indonesia. The findings suggest that informal navigation initiatives fill a gap left by formal initiatives, but have limited effects on systemic change or JKN responsiveness. More collaboration with JKN authorities is needed to advance equitable access to NHI.
Article
Economics
Nguyen Thi Thu Thuong
Summary: The study found a significant decline in the incidence and intensity of catastrophic health expenditure (CHE) and medical impoverishment in Vietnam over the study years. The increase in poverty gap was caused by non-poor households becoming poor after out-of-pocket health payments in 2012 and 2014, while existing poor households worsened after healthcare payments in 2008, 2010, 2016, and 2018. Additionally, health insurance had positive impacts on financial protection against CHE and impoverishment in Vietnamese households, suggesting the need for continued review and improvement of the health insurance scheme to promote equity and strengthen the health financing system.
ECONOMIC ANALYSIS AND POLICY
(2021)
Review
Medicine, General & Internal
Shin Enosawa
Summary: Stem cell therapy is a hot topic in medical science, and Japan is leading research and development in this field. Over the past decade, Japan has made progress in conducting clinical trials for various stem cell therapies and has established regulations and policies to support the development of this field at a national level.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Statistics & Probability
Xiudi Li, Sijia Li, Alex Luedtke
Summary: We introduce a framework to utilize external data for assessing the efficiency of covariate-adjusted estimators compared to unadjusted estimators in future randomized trials. The relative efficiencies obtained approximate the required sample size ratio for desired statistical power. We develop semiparametrically efficient estimators for various treatment effect estimands of interest, allowing for flexible statistical learning methods to estimate the nuisance functions. We propose a Wald-type confidence interval and a double bootstrap scheme for statistical inference. Simulation studies demonstrate the performance of the proposed methods, and they are applied to estimate the efficiency gain of covariate adjustment in Covid-19 therapeutic trials.
JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY
(2023)