Review
Medicine, General & Internal
Anna Louise Pouncey, Mark Woodward
Summary: Cardiovascular disease is the leading cause of death in women, with ischaemic heart disease, stroke, and peripheral arterial disease being major components. However, there is a lack of knowledge about the risk factors and efficacy of treatment in women, resulting in reduced opportunities for prevention and management.
Article
Peripheral Vascular Disease
Hirofumi Tomiyama, Takumi Imai, Kazuki Shiina, Yukihito Higashi, Hiroki Nakano, Takamichi Takahashi, Masatsune Fujii, Chisa Matsumoto, Akira Yamashina, Taishiro Chikamori
Summary: This study examines the association of cardiovascular risk factors (CVRFs) with the rate of progression of arterial stiffness based on long-term repeated measurements. Smoking, heavy alcohol intake, hypertension, diabetes, hypertriglyceridemia, and hyperuricemia were found to be independently associated with a fast progression of arterial stiffness, while lower values in certain biomarkers were associated with a slow progression. The findings highlight the importance of early interventions to control CVRFs in maintaining arterial health.
Review
Cell Biology
Giuseppe Pasqualetti, Tony Thayanandan, Paul Edison
Summary: Alzheimer's disease is a neurodegenerative disorder influenced by cardiometabolic and genetic risk factors. Cardiometabolic risk factors are associated with cognitive decline, while genetic factors are involved in neuropathological changes and cardiovascular damage.
AGEING RESEARCH REVIEWS
(2022)
Review
Endocrinology & Metabolism
Rohit Hariharan, Aya Mousa, Barbora de Courten
Summary: Variations in AMY1A copy numbers play an important role in obesity and related cardiometabolic disorders through their effects on glucose and lipid homeostasis, inflammatory markers, and the gut microbiome.
Review
Nutrition & Dietetics
Agata Stanek, Bogna Grygiel-Gorniak, Klaudia Brozyna-Tkaczyk, Wojciech Myslinski, Armand Cholewka, Samaneh Zolghadri
Summary: Arterial stiffness, an early indicator of increased cardiovascular disease risk, can be modified by dietary habits. A caloric-restricted diet in obese patients enhances aortic distensibility and decreases pulse wave velocity (PWV). High intake of saturated fatty acids (SFA), trans fats, and cholesterol impairs endothelial function and raises brachial-ankle PWV, while replacing SFA with monounsaturated (MUFA) or polyunsaturated fatty acids (PUFA) from seafood and plants decreases the risk of arterial stiffness. Consuming dairy products (except butter), complex carbohydrates with a low glycemic index, and a Mediterranean diet rich in fruits, vegetables, fish, and minimal red meat intake can help prevent arterial stiffness.
Article
Clinical Neurology
Sharon N. Poisson, Nancy K. Hills, Stephen Sidney, Heather J. Fullerton
Summary: Incidence of arterial ischemic stroke (AIS) has decreased overall in recent decades, but has increased in young adults. This study found that the risk factors associated with stroke in older adults are present in childhood and increase with age, highlighting the importance of early prevention and control of these risk factors.
Review
Hematology
Steve Raoul Noumegni, Clement Hoffmann, Cecile Tromeur, Romain Didier, Luc Bressollette, Karine Lacut, Francis Couturaud
Summary: This systematic review and meta-analysis identified risk factors of arterial events in patients with VTE, including male gender, diabetes, hypertension, previous atherothrombotic event, chronic kidney disease, cancer, and unprovoked VTE. These risk factors contribute to arterial ischemic events in VTE population.
THROMBOSIS AND HAEMOSTASIS
(2022)
Article
Medicine, General & Internal
Jakub Baran, Pawel Kleczynski, Lukasz Niewiara, Jakub Podolec, Rafal Badacz, Andrzej Gackowski, Piotr Pieniazek, Jacek Legutko, Krzysztof Zmudka, Tadeusz Przewlocki, Anna Kablak-Ziembicka
Summary: This study found that in patients with DAS, the values of RI and PI for vascular resistance were significantly higher compared to patients with CRF, and high RI and PI values were associated with an increased risk of HF-MACCE.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Guillermo Salib Coronel-Touma, Chiara Monopoli-Roca, Cristina Nicole Almeida-Ayerve, Susana Marcos-Alonso, Diana Gomez de la Torre-Morales, Jose Serradilla-Lopez, Santiago Santa Cruz-Ruiz, Angel Batuecas-Caletrio, Hortensia Sanchez-Gomez
Summary: This study analyzed the influence of age and cardiovascular risk factors on the evolution of vestibular neuritis. The results showed that CVRFs do not independently affect VOR gain in VN patients' follow-ups. However, age significantly impacts VOR gain in VN and could be modulated by gender and hypertension.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Jennifer J. Stuart, Lauren J. Tanz, Eric B. Rimm, Donna Spiegelman, Stacey A. Missmer, Kenneth J. Mukamal, Kathryn M. Rexrode, Janet W. Rich-Edwards
Summary: This study aimed to evaluate the association between hypertensive disorders of pregnancy (HDP) and long-term cardiovascular disease (CVD) and identify the proportion mediated by established CVD risk factors. The results showed that women with HDP during their first pregnancy had a higher risk of CVD, which was mainly mediated by established CVD risk factors.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Multidisciplinary Sciences
Agne Laucyte-Cibulskiene, Chen-Huan Chen, John Cockroft, Pedro G. Cunha, Maryam Kavousi, Aleksandras Laucevicius, Maria Lorenza Muiesan, Ernst R. Rietzschel, Ligita Ryliskyte, Irina D. Strazhesko, Charalambos Vlachopoulos, Jorge Cotter, Ekatherina N. Dudinskaya, Nichola Gale, Fariba Ahmadizar, Francesco U. S. Mattace-Raso, Maggie Munnery, Pedro Oliveira, Anna Paini, Massimo Salvetti, Olga N. Tkacheva, Edward G. Lakatta, Peter M. Nilsson, Angelo Scuteri
Summary: This study aimed to investigate the effect of metabolic syndrome (MetS) and its components on central blood pressure (CBP). The results showed that individuals with MetS were 50% more likely to have higher CBP. Furthermore, specific clusters of MetS components were found to be associated with higher CBP, with some associations being more significant in women.
SCIENTIFIC REPORTS
(2022)
Article
Cardiac & Cardiovascular Systems
Pierre Boutouyrie, Phil Chowienczyk, Jay D. Humphrey, Gary F. Mitchell
Summary: Arterial stiffness is a key marker of risk in hypertension, and can be measured at material or structural levels. Studies have shown that structural stiffness predicts outcomes, with elastic arteries being most sensitive to blood pressure and age. Stiffness is considered an index of vascular aging and affects brain, kidneys, and heart function. Reduction of stiffness through antihypertensive treatments and preventive drugs may have additional benefits beyond lowering blood pressure. Newer anti-inflammatory drugs also have effects on stiffness independent of blood pressure.
CIRCULATION RESEARCH
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Aleksander Kosmala, Sebastian E. Serfling, Kerstin Michalski, Thomas Lindner, Andreas Schirbel, Takahiro Higuchi, Philipp E. Hartrampf, Thorsten Derlin, Andreas K. Buck, Alexander Weich, Rudolf A. Werner
Summary: The purpose of this study was to assess the prevalence, distribution, and intensity of in-vivo arterial wall fibroblast activation protein (FAP) uptake, and its correlation with calcified plaque burden, cardiovascular risk factors (CVRFs), and FAP-avid tumor burden. The study found a significant correlation between FAP uptake and calcified plaque burden, but inconsistent correlation with cardiovascular risk factors.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Article
Medicine, General & Internal
Gabriela Goncalves-Martins, Daniel Gil-Sala, Cristina Tello-Diaz, Xavier Tenezaca-Sari, Carlos Marrero, Teresa Puig, Raquel Gayarre, Joan Fite, Sergi Bellmunt-Montoya
Summary: The study found independent strong associations between male smokers and diabetes, as well as female smokers and hypertension, with peripheral arterial disease (PAD) prevalence. Male subjects presented with higher REGICOR scores and should be considered high-risk groups for screening programs.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Drazen Bedekovic, Damir Kirner, Ivica Bosnjak, Aleksandar Kibel, Sandra Saric, Srdan Novak, Visnja Prus
Summary: Rheumatoid arthritis (RA) increases the risk of cardiovascular diseases (CVDs), mainly due to arterial hypertension (HT). However, this study found no difference in HT prevalence between RA and osteoarthritis (OA) groups, but the RA group had a higher incidence of CVDs. RA patients with long-term remission had a slightly lower HT prevalence.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Satish Ramkumar, Hiroshi Kawakami, Edmond Wong, Mark Nolan, Thomas H. Marwick
Summary: This study compared the cost-effectiveness of two screening strategies for atrial fibrillation and found that imaging-guided screening was more cost-effective with lower costs and better outcomes. The study suggests that targeted screening for specific populations based on clinical and imaging risk parameters is more meaningful for detecting atrial fibrillation.
INTERNAL MEDICINE JOURNAL
(2023)
Review
Cardiac & Cardiovascular Systems
Edgar M. Hidalgo, Leah Wright, Mats Isaksson, Gavin Lambert, Thomas H. Marwick
Summary: With advances in robotics and telecommunications, robot-assisted teleoperated ultrasound examination can help with medical diagnosis in remote areas, reducing health inequalities. Studies have shown that robots can safely perform ultrasound examinations by following the hand movements of sonographers and researchers. However, real-time transmission of video and ultrasound images requires high bandwidth, and improvements are needed in robot control and interface design.
JACC-CARDIOVASCULAR IMAGING
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Thomas H. Marwick, Y. Chandrashekhar
JACC-CARDIOVASCULAR IMAGING
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Neville Tan, Thomas H. Marwick, Nitesh Nerlekar
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Review
Cardiac & Cardiovascular Systems
Neville Tan, Damini Dey, Thomas H. Marwick, Nitesh Nerlekar
Summary: Coronary computed tomography can quantify coronary inflammation by mapping changes in pericoronary adipose tissue, but there are significant knowledge gaps in its interpretation.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Health Care Sciences & Services
James A. Black, Conor Lees, Niamh Chapman, Liam Kelleher, Julie A. Campbell, Petr Otahal, Kevin Cheng, Thomas H. Marwick, James E. Sharman
Summary: This study evaluated the effectiveness of a telehealth chest pain clinic established during the COVID-19 pandemic. The results showed that telehealth patients had a reduced need for additional testing compared to face-to-face consultations, and achieved similar clinical outcomes with high patient satisfaction.
TELEMEDICINE AND E-HEALTH
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Y. Chandrashekhar, Thomas H. Marwick, Leslee J. Shaw
JACC-CARDIOVASCULAR IMAGING
(2023)
Review
Cardiac & Cardiovascular Systems
Joshua Wong, Stacey Peters, Thomas H. Marwick
Summary: Heart failure is a heterogeneous disease, and genetic testing provides additional information to imaging in distinguishing phenotypes. Advances in genetic testing have identified harmful variants in specific heart failure phenotypes (dilated cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy, and hypertrophic cardiomyopathy), with implications for specific treatments. However, the diagnostic yield of genetic testing is modest, and many rare variants have incomplete penetrance and variable expressivity. The heterogeneity of the heart failure phenotype is also influenced by environmental factors and co-morbidities. Future research should focus on the cumulative impact of genetic polymorphisms on the development of heart failure.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Mohammad Shah, Marie-Jeanne Buscot, Jing Tian, Hoang T. Phan, Brooklyn J. Fraser, Thomas H. Marwick, Terence Dwyer, Alison Venn, Seana Gall
Summary: This study analyzed long-term follow-up data from the Australian Schools Health and Fitness Survey and found that childhood risk factors contribute to sex differences in adult carotid artery plaques and intima-media thickness. After adjusting for relevant adult risk factors, the sex differences decreased. The conclusion is that prevention strategies throughout the life course are important for reducing sex differences in cardiovascular diseases.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Paaladinesh Thavendiranathan, Christian Houbois, Thomas H. Marwick, Tiffanie Kei, Sudipta Saha, Kyle Runeckles, Flora Huang, Tamar Shalmon, Kevin E. Thorpe, Rossanna C. Pezo, Anca Prica, Dawn Maze, Husam Abdel-Qadir, Kim A. Connelly, Joyce Chan, Filio Billia, Coleen Power, Kate Hanneman, Bernd J. Wintersperger, Christine Brezden-Masley, Eitan Amir
Summary: This study aimed to assess whether statins can prevent decline in left ventricular ejection fraction in patients treated with anthracyclines. The results showed that primary prevention with atorvastatin did not ameliorate early decline in LVEF, left ventricular remodeling, therapy-related cardiac dysfunction, changes in serum cardiac biomarkers, or myocardial tissue changes in patients at increased risk of CTRCD.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY
(2023)
Article
Computer Science, Artificial Intelligence
Chadi Ghafari, Khalil Houissa, Jo Dens, Claudiu Ungureanu, Peter Kayaert, Cyril Constant, Stephane Carlier
Summary: This study compares the image results of two enhanced stent imaging systems (StentBoost and CAAS StentEnhancer) qualitatively and quantitatively measures the deployed stent diameters using quantitative coronary angiography (QCA) and CAAS StentEnhancer software. The results show that CAAS StentEnhancer provides better visualization and allows precise assessment of stent expansion, especially when there are overlapping coronary side branches.
Article
Cardiac & Cardiovascular Systems
Roberto Enrique Azcui Aparicio, Melinda J. Carrington, Quan Huynh, Jocasta Ball, Thomas H. Marwick
Summary: The study investigated the association between Fuster-BEWAT Score (FBS), Framingham Risk Score (FRS), and Pooled Cohort Equation (PCE) with carotid plaque presence, aiming to develop a stepped screening process for the primary prevention of cardiovascular disease (CVD). The results showed that FBS was able to identify carotid plaque in asymptomatic individuals, suggesting its potential use in initial risk delineation could improve patient selection for further assessment and reduce cost and time.
CARDIOVASCULAR DIGITAL HEALTH JOURNAL
(2023)
Review
Oncology
Yueyang Bao, John Lee, Udit Thakur, Satish Ramkumar, Thomas H. Marwick
Summary: This study compared the atrial fibrillation (AF) detection rate between cancer survivors and the general population and found that the AF risk in cancer survivors was not significantly increased.
Article
Medicine, General & Internal
Quan Huynh, Noah Wexler, Joel Smith, Leah Wright, Felicia Ho, Richard Allwood, Yusuke Sata, Stefano Manca, Erin Howden, Thomas H. Marwick
Summary: This study compared the symptoms and functional impairment of patients with previous COVID-19 infection to uninfected community controls. It found that patients with COVID-19 had lower functional capacity and more depression compared to controls. A pilot group also showed an increase in peak workload after exercise training. The study suggests that an exercise training program might be beneficial for selected patients.
INTERNAL MEDICINE JOURNAL
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Neville Tan, Nitesh Nerlekar, Thomas H. Marwick
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)