Article
Environmental Sciences
Jacopo La Nasa, Tommaso Lomonaco, Enrico Manco, Alessio Ceccarini, Roger Fuoco, Andrea Corti, Francesca Modugno, Valter Castelvetro, Ilaria Degano
Summary: This study utilized SIFT-MS technology to characterize the VOCs released from plastic debris collected from a sandy beach in northern Tuscany, Italy. The results demonstrate the significant potential of this non-destructive method in studying microplastic pollution and its harmful effects.
Article
Biochemical Research Methods
Yoshie Nakayama, Mariko Hanada, Hiroshi Koda, Masahiro Sugimoto, Masahiro Takada, Masakazu Toi
Summary: This study aimed to evaluate volatile compounds in exhaled breath as a non-invasive screening method to detect breast neoplasms. After analyzing breath samples, significant differences in volatile compounds were found between patients with breast cancer and non-breast cancer controls. The developed MLR model can effectively discriminate between breast cancer and non-breast cancer samples. This study suggests the potential of volatile compounds in exhaled breath as a noninvasive screening method for breast cancer.
JOURNAL OF BREATH RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Wai Hong Wilson Tang, Lily Tranchito, Chonyang Albert, Zeynep G. Gul, Frank S. Cikach, David Grove, Yuping Wu, Raed A. Dweik
Summary: Elevated levels of exhaled breath acetone are associated with poorer outcomes in heart failure patients, while reductions in acetone and pentane levels correlate with weight loss.
Article
Engineering, Environmental
Thomas Virdis, Christophe Walgraeve, Angelos Ioannidis, Herman Van Langenhove, Joeri F. M. Denayer
Summary: Metal-Organic Frameworks (MOFs) have been extensively researched for applications like gas storage and heterogeneous catalysis, but the study of VOCs adsorption on MOFs is still behind compared to traditional adsorbent materials. This research used innovative methods to explore VOCs adsorption on MOFs at ultra-low concentrations, finding that UiO-66 exhibited higher uptake compared to ZIF-8 and both MOFs showed preference for hydrophobic molecules.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Chemistry, Analytical
Mylene Ghislain, Marine Reyrolle, Jean-Marc Sotiropoulos, Thierry Pigot, Mickael Le Bechec
Summary: SIFT-MS utilizes ion-molecule reactions to achieve direct and rapid analysis of volatile organic compounds in the gas phase, with observations of various chemical reaction characteristics during experiments.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Applied
Mourad Kharbach, Huiwen Yu, Rabie Kamal, Ilias Marmouzi, Katim Alaoui, Joeri Vercammen, Abdelaziz Bouklouze, Yvan Vander Heyden
Summary: This study successfully identified adulterants in extra-virgin Argan Oil (EVAO) and evaluated the degree of adulteration using Selected-Ion Flow-Tube Mass Spectrometry (SIFT-MS) spectra and chemometric tools. The results demonstrated the effectiveness of SIFT-MS spectra in quality evaluation of EVAO.
Article
Chemistry, Multidisciplinary
Elina Gashimova, Azamat Temerdashev, Vladimir Porkhanov, Igor Polyakov, Dmitry Perunov, Ekaterina Dmitrieva
Summary: Development of simple, fast, and non-invasive tests for lung cancer diagnostics is crucial in clinical practice. This paper explores the use of exhaled breath and skin as potential objects for diagnosing lung cancer, and develops diagnostic models using machine learning algorithms. The results show that artificial neural networks perform well in classifying lung cancer patients and healthy individuals. Additionally, the study identifies significant differences in parameters in exhaled breath samples of lung cancer patients and evaluates the potential of skin analysis for lung cancer diagnosis.
Article
Chemistry, Analytical
Karen Segers, Amorn Slosse, Johan Viaene, Michiel A. G. E. Bannier, Kim D. G. Van de Kant, Edward Dompeling, Ann Van Eeckhaut, Joeri Vercammen, Yvan Vander Heyden
Summary: SIFT-MS has shown potential in clinical diagnosis with different data analysis strategies for distinguishing three classes of breath samples. The study found that DOSC preprocessing achieved perfect models but with uncertainty, while other preprocessing methods need further investigation.
Article
Health Care Sciences & Services
Adnan Azim, Faisal Rezwan, Clair Barber, Matthew Harvey, Ramesh J. Kurukulaaratchy, John W. Holloway, Peter H. Howarth
Summary: The measurement of exhaled volatile organic compounds (VOCs) in exhaled breath is a promising biomarker for airways disease. This study found good short-term repeatability of VOC measurements in severe asthma patients, indicating its sensitivity to airway inflammation. A novel variance-based feature selection tool was also introduced to improve machine learning model predictions.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Chemistry, Analytical
Elina Gashimova, Anna Osipova, Azamat Temerdashev, Vladimir Porkhanov, Igor Polyakov, Dmitry Perunov, Ekaterina Dmitrieva
Summary: Gas chromatography-mass spectrometry and electronic nose were used to analyze the exhaled breath of 40 lung cancer patients and 40 healthy individuals. While GC-MS could identify significant differences between groups, the electronic nose was unable to distinguish the samples. Diagnostic models showed varying sensitivity and specificity in training and test data.
ANALYTICAL METHODS
(2021)
Article
Food Science & Technology
Mickael Le Bechec, Marine Reyrolle, Valerie Chesneau, Marine Breuil, Valerie Desauziers
Summary: This study used selected ion flow tube-mass spectrometry (SIFT-MS) analysis to explore caviar products. The results showed that the volatile profile and sensory perception of caviar are influenced by factors such as sturgeon species, production sites, water quality, production seasonality, and storage time. This study demonstrated the potential of SIFT-MS as a strategic decision-making support tool for sturgeon producers.
Article
Chemistry, Multidisciplinary
Bhamini Vadhwana, Jack James, Melina Pelling, Ilaria Belluomo, Piers R. Boshier, George B. Hanna
Summary: Analysis of salivary VOCs may provide a noninvasive method for disease detection. This study optimized saliva headspace VOC analysis and assessed longitudinal variation of salivary VOCs. The method of saliva collection and other factors influenced VOC detection, and certain compounds showed variability suggesting the influence of potential external factors. Overall, there was an acceptable range of inter- and intraindividual VOC variability, and standardization with morning sampling after a 6 h fast is recommended.
APPLIED SCIENCES-BASEL
(2023)
Article
Chemistry, Multidisciplinary
Colin Hastie, Adrian Thompson, Mark Perkins, Vaughan S. Langford, Michael Eddleston, Natalie Z. M. Homer
Summary: Self-poisoning with professional agricultural pesticide products accounts for about 20% of global suicides, with the majority occurring in South Asia and China. Faster detection of co-formulants can aid in early identification of pesticide poisoning and reduce mortality rates. SIFT-MS, a direct mass spectrometry technique, shows great promise as an alternative analytical tool for analyzing cyclohexanone and cyclohexanol in plasma, providing higher sample throughput compared to conventional GC/MS methods.
Article
Environmental Sciences
Sunil Paul M. Menacherry, Martin Kocarek, Tereza Kacerova, Zora Kotikova, Petr Kacer, Radka Kodesova
Summary: The study aimed to investigate the effects of different initial concentrations on the stability and degradation of three pharmaceutical compounds in soil. Results showed that the dissipation rate of the compounds varied with initial concentrations, with carbamazepine and sertraline degrading faster at higher concentrations, and metoprolol degrading faster at lower concentrations. The study concluded that while initial concentrations influence dissipation, there was no clear trend in the results, indicating the need for further research to fully understand the transformation mechanism.
JOURNAL OF SOILS AND SEDIMENTS
(2022)
Review
Spectroscopy
David Smith, Patrik Spanel, Nicholas Demarais, Vaughan S. S. Langford, Murray J. J. McEwan
Summary: SIFT-MS is a versatile analytical technique for the identification and quantification of trace gases. It has a wide range of applications, including real-time analysis of humid exhaled breath and air quality monitoring in industrial scenarios. The addition of reagent anions in SIFT-MS instruments has enhanced the analytical capability, allowing analysis of volatile compounds in humid air that cannot be done using reagent cations alone.
MASS SPECTROMETRY REVIEWS
(2023)