Article
Chemistry, Physical
Atul Verma, Yi-An Hong, Anren Hu, Yen-Pei Fu
Summary: Optimization of Cu2O morphology using NH4OH has rarely been explored. In this study, the influence of NH4OH on Cu2O morphology was investigated, and the spherical shape was transformed into octahedron-like octaspheres. The {100} facets at the corners of the Cu2O octaspheres could be etched. The morphology variations and facet etchings were studied using FESEM images and XRD analysis, showing a peak shift in Cu2O (111). Cu2O was then hybridized with rGO and g-C3N4 to form a ternary hybrid CGR, which effectively degraded the antibiotic pollutant tetracycline.
APPLIED SURFACE SCIENCE
(2023)
Article
Chemistry, Analytical
Wanzhen Han, Shiyu Du, Caowei Tang, Yiling Li, Ting Jiang, Wei Xu
Summary: The integration of a liquid-phase ion trap with a miniature mass spectrometer improves detection sensitivity and enables enrichment and separation of ions, making it suitable for the analysis of low abundant target molecules.
ANALYTICA CHIMICA ACTA
(2022)
Article
Biochemical Research Methods
Yuyang Zhang, Wanru Li, Haoran Lei, Xueming Dong, Hilkka Kenttaemaa
Summary: Asphaltenes in heavy crude oil contain nitrogen-containing heteroaromatic compounds that can deactivate catalysts in refinery processes. This study developed an analytical approach using mass spectrometry to differentiate isomeric molecular radical cations of n-pentylquinoline and understand their fragmentation pathways. The results showed distinct fragmentation patterns depending on the location of the alkyl side chain in the quinoline ring, and quantum chemical calculations were used to explain the observed mechanisms. This approach will facilitate the structural characterization of nitrogen-containing heteroaromatic compounds in asphaltenes.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2023)
Article
Chemistry, Analytical
Qian Xu, Jie Hong, Siyu Liu, Yanbing Zhai, Wei Xu
Summary: A miniature protein mass spectrometer was developed for rapid identification of proteins and their conformations, with high mass resolution and sensitivity. Coupling the instrument with a soft electrospray ionization source allowed the acquisition of mass spectra of native proteins.
Article
Chemistry, Analytical
Hongjia Zhang, Heyuan Jia, Zhiwu Gao, Yu Xiang, Ting Jiang, Wei Xu
Summary: With improved analytical performances, miniature mass spectrometers are widely used in various applications. High throughput analysis of multi-targets is crucial, especially for in-situ applications. In this study, parallel pseudo-MRM mode was developed on a brick miniature mass spectrometer, significantly increasing the throughput for multi-target screening. The method was successfully applied for target screening and quantitative analysis.
Article
Engineering, Aerospace
Illia Zymak, Jan Zabka, Miroslav Polasek, Arnaud Sanderink, Jean-Pierre Lebreton, Bertrand Gaubicher, Barnabe Cherville, Anna Zymakova, Christelle Briois
Summary: A new laboratory Orbitrap mass spectrometer called OLYMPIA has been developed and used to test and develop technologies for the next generation of spaceborne mass spectrometers. It has also been used to study high-resolution space-relevant chemical processes.
Article
Biochemistry & Molecular Biology
Chaohong Feng, Siyu Liu, Ting Jiang, Wei Xu
Summary: This article introduces a mass spectrometer based on a single mass analyzer that can achieve both quadrupole and ion trap operation modes. By designing and integrating a multi-electrode quadrupole-ion trap mass analyzer and two ionization sources, analysis of low-mass ions and high-mass ions with high sensitivity, mass resolution, and mass range can be achieved.
Review
Astronomy & Astrophysics
J. Simcic, D. Nikolic, A. Belousov, D. Atkinson, C. Lee, S. Madzunkov, D. Almodiel
Summary: This paper introduces the types of mass spectrometers used for the study of solar system bodies' atmospheres, as well as the requirements for future small probe missions. Important composition measurements for ice giant atmospheres include helium, noble gases, and other key isotopes, with the inherent challenge of operating in the atmospheric layers of Neptune and Uranus. The QITMS developed by JPL is a compact and efficient mass spectrometer suitable for planetary exploration and surface sample research.
SPACE SCIENCE REVIEWS
(2021)
Article
Biochemical Research Methods
Anton Belousov, Morgan Miller, Robert Continetti, Stojan Madzunkov, Jurij Simcic, Dragan Nikolic, Frank Maiwald, Sarah Waller, Michael Malaska, Morgan Cable
Summary: The Enceladus plume is a target of astrobiological interest as it may carry signs of extraterrestrial life. To simulate fly-through conditions, researchers are developing an ice grain accelerator coupled with a mass spectrometer. Initial observations show brief increases in water molecule abundance during ice grain impacts.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2021)
Article
Biochemical Research Methods
Takashi Baba, Zoe Zhang, Suya Liu, Lyle Burton, Pavel Ryumin, J. C. Yves Le Blanc
Summary: We present a method to comprehensively characterize multiple glycosylations in glycopeptide isoforms. Using hot electron capture dissociation (hot ECD) in liquid chromatography-tandem mass spectrometry, we detected varying abundances of different O-glycoforms in isomeric glycopeptides. To capture low abundant glycosylated species, we utilized a prototype of a ZenoTOF 7600 system with an efficient electron-activated dissociation device in targeted or scheduled high-resolution multiple reaction monitoring workflows. Our method identified 69 O-glycopeptides with relative abundance ranging from 100 to 0.2%, including sialylated glycans with Neu5Ac and Neu5Gc.
JOURNAL OF PROTEOME RESEARCH
(2022)
Article
Biochemical Research Methods
Ying-Jie He, Ying Zhou, Yan Qin, Zhong-Shun Zhou, Meng Zhu, Yan-Yan Zhu, Zhao-Jie Wang, Tian-Zhen Xie, Li-Xing Zhao, Xiao-Dong Luo
Summary: This study focused on improving the accuracy of structural annotation of candidate structures by integrating multiple levels in LC-HRMS analysis, successfully validating the feasibility of the approach for precise identification of citrus flavanones in biological samples.
PHYTOCHEMICAL ANALYSIS
(2021)
Article
Chemistry, Analytical
Erik Saparbaev, Ruslan Yamaletdinov, Oleg Boyarkin
Summary: The diverse structures and isomeric nature of lipids provide a wide range of functions in nature, but also present challenges in identification. By using cold ion UV fragmentation spectroscopy of noncovalent complexes with aromatic amino acids and dipeptides, isomeric lipids can be distinguished and quantified. Preselected aromatic sensors sensitive to specific isomers have been used to accurately determine relative concentrations of isomeric glycerophospholipids mixed in solution.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Chad R. Weisbrod, Lissa C. Anderson, Christopher L. Hendrickson, Leah Schaffer, Michael R. Shortreed, Lloyd M. Smith, Jeffrey Shabanowitz, Donald F. Hunt
Summary: PTR combined with PIP technology can significantly improve the spectral S/N of intact proteins and accelerate mass spectrometry analysis. Rapid park can increase reaction rates by 5-10x and improve tandem MS sequencing speed by reducing ion injection time.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
L. Chang, X. I. E. Jie, L. I. U. Mei-Ying, H. U. A. N. G. Ze-Jian, D. A. Xin-Hua, J. I. A. N. G. You, F. A. N. G. Xiang, T. I. A. N. Di
Summary: A quadrupole-dual pressure linear ion trap (Q-DPLIT) tandem mass spectrometer was developed to improve sensitivity and accuracy. The instrument consisted of a quadrupole and two hyperbolic ion traps in axial series. The Q-DPLIT successfully trapped 4.2 times more reserpine ions compared to the Q-LIT. The combination of Q-DPLIT and simultaneous technique improved the signal intensity by 1.3-10 times and increased the linear correlation coefficient from 0.6693-0.9449 to 0.9942-0.9994.
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
(2023)
Article
Physics, Multidisciplinary
P. Filianin, C. Lyu, M. Door, K. Blaum, W. J. Huang, M. Haverkort, P. Indelicato, C. H. Keitel, K. Kromer, D. Lange, Y. N. Novikov, A. Rischka, R. X. Schuessler, Ch. Schweiger, S. Sturm, S. Ulmer, Z. Harman, S. Eliseev
Summary: In this study, the cyclotron frequency ratio of Os-187(29+) to Re-187(29+) ions was measured with the Penning-trap mass spectrometer PENTATRAP, resulting in the most precise measurement to date. The total binding-energy difference of the 29 missing electrons in Re and Os was calculated, yielding a value of 53.5(10) eV. Finally, using the achieved results, the mass difference between neutral 187Re and Os-187, i.e., the Q value of the beta(-) decay of Re-187, was determined to be 2470.9(13) eV.
PHYSICAL REVIEW LETTERS
(2021)