Defining a comprehensive verotype using electronic health records for personalized medicine

Automating the Study of Population Variation of Electrocardiographic Features

(2013) Isaac S. Kohane   CIRCULATION

Genome- and Phenome-Wide Analyses of Cardiac Conduction Identifies Markers of Arrhythmia Risk

(2013) Marylyn D. Ritchie et al.   CIRCULATION

ICD-9 tobacco use codes are effective identifiers of smoking status

(2013) Laura K Wiley et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Deep phenotyping for precision medicine

(2012) Peter N. Robinson   HUMAN MUTATION

Building a robust, scalable and standards-driven infrastructure for secondary use of EHR data: The SHARPn project

(2012) Susan Rea et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Parkinson's disease subtypes: lost in translation?

(2012) C. Marras et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Complex-disease networks of trait-associated single-nucleotide polymorphisms (SNPs) unveiled by information theory

(2012) Haiquan Li et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Importance of multi-modal approaches to effectively identify cataract cases from electronic health records

(2012) Peggy L Peissig et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

An integrated approach to identify causal network modules of complex diseases with application to colorectal cancer

(2012) Zhenshu Wen et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Next-generation phenotyping of electronic health records

(2012) G. Hripcsak et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Leveraging models of cell regulation and GWAS data in integrative network-based association studies

(2012) Andrea Califano et al.   NATURE GENETICS

Mining electronic health records: towards better research applications and clinical care

(2012) Peter B. Jensen et al.   NATURE REVIEWS GENETICS

Unsupervised Analysis of Classical Biomedical Markers: Robustness and Medical Relevance of Patient Clustering Using Bioinformatics Tools

(2012) Michal Markovich Gordon et al.   PLoS One

Population Physiology: Leveraging Electronic Health Record Data to Understand Human Endocrine Dynamics

(2012) D. J. Albers et al.   PLoS One

Electronic health records: Implications for drug discovery

(2011) Lixia Yao et al.   DRUG DISCOVERY TODAY

Protein-network modeling of prostate cancer gene signatures reveals essential pathways in disease recurrence

(2011) James L Chen et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Using electronic health records to drive discovery in disease genomics

(2011) Isaac S. Kohane   NATURE REVIEWS GENETICS

Rare De Novo Variants Associated with Autism Implicate a Large Functional Network of Genes Involved in Formation and Function of Synapses

(2011) Sarah R. Gilman et al.   NEURON

Electronic Medical Records for Genetic Research: Results of the eMERGE Consortium

(2011) A. N. Kho et al.   Science Translational Medicine

Fasting plasma and CSF amino acid levels in amyotrophic lateral sclerosis: a subtype analysis

(2010) W. Camu et al.   ACTA NEUROLOGICA SCANDINAVICA

PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations

(2010) J. C. Denny et al.   BIOINFORMATICS

An FDA bioinformatics tool for microbial genomics research on molecular characterization of bacterial foodborne pathogens using microarrays

(2010) Hong Fang et al.   BMC BIOINFORMATICS

Development and Validation of an Electronic Health Record-Based Chronic Kidney Disease Registry

(2010) S. D. Navaneethan et al.   Clinical Journal of the American Society of Nephrology

Genotype–phenotype associations and human eye color

(2010) Désirée White et al.   JOURNAL OF HUMAN GENETICS

Multi-Phase Defense by the Big-Headed Ant,Pheidole obtusospinosa, Against Raiding Army Ants

(2010) Ming H. Huang   JOURNAL OF INSECT SCIENCE

Clinical subtypes of Parkinson's disease

(2010) Stephanie M. van Rooden et al.   MOVEMENT DISORDERS

Network medicine: a network-based approach to human disease

(2010) Albert-László Barabási et al.   NATURE REVIEWS GENETICS

Deep phenotyping to predict live birth outcomes in in vitro fertilization

(2010) P. Banerjee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A clinico-pathological study of subtypes in Parkinson's disease

(2009) M. Selikhova et al.   BRAIN

Common statistical issues in genome-wide association studies: a review on power, data quality control, genotype calling and population structure

(2009) Yik Y Teo   CURRENT OPINION IN LIPIDOLOGY

‘Deep phenotyping’: characterizing populations in the era of genomics and systems biology

(2009) Russell P Tracy   CURRENT OPINION IN LIPIDOLOGY

A network medicine approach to human disease

(2009) Andreas Zanzoni et al.   FEBS LETTERS

Biological Processes Associated with Breast Cancer Clinical Outcome Depend on the Molecular Subtypes

(2008) C. Desmedt et al.   CLINICAL CANCER RESEARCH

Genetic Mapping in Human Disease

(2008) D. Altshuler et al.   SCIENCE

Ovarian Carcinoma Subtypes Are Different Diseases: Implications for Biomarker Studies

(2008) Martin Köbel et al.   PLOS MEDICINE

Identifying Smokers with a Medical Extraction System

(2007) C. Clark et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Identifying Patient Smoking Status from Medical Discharge Records

(2007) O. Uzuner et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION