Article
Clinical Neurology
Ignacio Elizagaray-Garcia, Gabriela F. Carvalho, Tibor M. Szikszay, Waclaw M. Adamczyk, Gonzalo Navarro-Fernandez, Paula Alvarez-Testillano, Javier Diaz-de-Teran, Kerstin Luedtke, Alfonso Gil-Martinez
Summary: The study compared psychophysical aspects of patients with chronic migraine, chronic tension-type headache, and headache-free controls, finding that neck disability was a significant predictor of headache frequency for both chronic tension-type headache and chronic migraine.
Article
Clinical Neurology
Inna E. Tchivileva, Richard Ohrbach, Roger B. Fillingim, Feng-Chang Lin, Pei Feng Lim, Samuel J. Arbes, Gary D. Slade
Summary: Headache attributed to Temporomandibular Disorder (HATMD) is a common secondary headache among patients with chronic myogenous TMD and primary headaches, often presenting as migraine. Unlike primary headaches, HATMD is associated with higher headache frequency and examination-evoked masticatory muscle pain, but surprisingly few measures of facial pain, general health, and psychological distress. Understanding these differences is important for developing targeted strategies for HATMD management.
JOURNAL OF HEADACHE AND PAIN
(2021)
Review
Oncology
Carolyn A. Bernstein
Summary: This review article provides a comprehensive overview of headache evaluation and treatment in cancer patients, including the diagnostic process, common types of headaches, pharmacological treatment, and complementary and integrative therapies.
Review
Food Science & Technology
Katarzyna Kepczynska, Izabela Domitrz
Summary: This article presents the common types of headaches and the effects of botulinum toxin in their treatment. Tension-type headache and migraine are the most common types of headaches, and botulinum toxin has shown significant benefits in treating chronic headaches. However, there is still a lack of evidence for its use in other types of headaches.
Article
Medicine, General & Internal
Iwona Rosciszewska-Zukowska, Sabina Galiniak, Halina Bartosik-Psujek
Summary: The aim of this study was to assess the prevalence and characteristics of headaches in Multiple Sclerosis (MS) patients treated with disease-modifying therapies (DMTs). The study found that more than half of MS patients experienced headaches, with the prevalence of migraines being almost three times higher than tension-type headaches. Migraines in MS patients had high severity and typical migraine characteristics.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Anesthesiology
Heejin Lee, Saeyoon Kim, Min Cheol Chang
Summary: According to this study, migraine in children and adolescents is more associated with depression, while tension-type headache (TTH) is more associated with anxiety. Therefore, it is important to consider psychological symptoms in the diagnosis and treatment of primary headache disorders.
Article
Medicine, Research & Experimental
Katharina Schiller, Markus Rauchenzauner, Tamir Avidgor, Sana Hannan, Carlo Lorenzen, Manuela Kaml, Gerald Walser, Iris Unterberger, Vera Filippi, Gregor Broessner, Gerhard Luef
Summary: This study examined the distribution of different primary headache disorders in a large cohort of patients with diagnosed epilepsy. The most common headache types in epilepsy patients were migraine and tension-type headache. Female epilepsy patients reported headaches significantly more often than male patients. Monotherapy in antiepileptic drugs (AEDs) might have a beneficial effect on the frequency of headache compared to polytherapy.
EUROPEAN JOURNAL OF MEDICAL RESEARCH
(2023)
Review
Chemistry, Multidisciplinary
Aida Herranz-Gomez, Irene Garcia-Pascual, Pablo Montero-Iniesta, Roy La Touche, Alba Paris-Alemany
Summary: Manual therapy and aerobic exercise have significant intervention effects on pain intensity and quality of life in patients with migraines, tension-type headaches, and cervicogenic headaches, while the effects on pain frequency and disability vary.
APPLIED SCIENCES-BASEL
(2021)
Article
Clinical Neurology
Rhannon Lobo, Mu Wang, Sean Lobo, Anish Bahra
Summary: New daily persistent headache is a challenging condition characterized by daily headache from onset. A study conducted in London found that most patients experienced chronic migraine, with a subset also experiencing thunderclap-onset headache. Factors like aura types, prior headache history, and premorbid disorders were also observed in the study cohort. Improvement was seen in a small percentage of patients, with some responding well to preventative medications like amitriptyline.
Article
Food Science & Technology
Mariarosaria Valente, Christian Lettieri, Valentina Russo, Francesco Janes, Gian Luigi Gigli
Summary: Chronic pain syndromes lead to changes in cortical excitability and plasticity in patients, as shown in a study using transcranial magnetic stimulation (TMS) in chronic migraine (CM) patients treated with botulinum neurotoxin type A (BoNT/A). Patients with CM showed lower cortical excitability and increased intracortical facilitation (ICF) compared to those with episodic migraine (EM). After BoNT/A treatment, there was a partial reduction in cortical excitability and a significant decrease in MIDAS score, indicating long-term alteration of cortical plasticity in chronic pain.
Article
Medicine, General & Internal
Chenghui Pi, Yinglu Liu, Lingling Li, Wenjing Tang, Xin Yan, Shengyuan Yu
Summary: This systematic review and meta-analysis examined the effects of non-pharmacological treatments on acute headaches in patients with episodic migraine and tension-type headache. The results showed that neuromodulation, acupuncture, and aerobic exercises were associated with reduced headache symptoms. However, further high-quality studies are needed for more detailed conclusions.
Review
Orthopedics
Mohammadreza Pourahmadi, Jan Dommerholt, Cesar Fernandez-de-Las-Penas, Bart Willem Koes, Mohammad Ali Mohseni-Bandpei, Mohammad Ali Mansournia, Somayeh Delavari, Abbasali Keshtkar, Mehrdad Bahramian
Summary: Dry needling does not show significant advantages in short-term relief of headache pain intensity for patients with TTH and CGH, but is more effective in improving related disabilities. Further high-quality studies are needed.
Article
Clinical Neurology
Tathiana Correa Rangel, Maria Cristina Falcao Raposo, Pedro Augusto Sampaio Rocha-Filho
Summary: There is a possible association between migraine, anxiety, and depression with insomnia in university students, but not with tension-type headache. The severity of insomnia is positively correlated with the impact and frequency of headaches.
Article
Clinical Neurology
Laura Rapisarda, Michele Trimboli, Francesco Fortunato, Antonio De Martino, Oreste Marsico, Giulio Demonte, Antonio Augimeri, Angelo Labate, Antonio Gambardella
Summary: The study examined headache variations related to intensive facemask usage among healthcare professionals in Italy, with some previously headache-free individuals developing de novo headaches and existing primary headache disorders exacerbating, especially for those with migraine.
NEUROLOGICAL SCIENCES
(2021)
Article
Orthopedics
Kiran Satpute, Nilima Bedekar, Toby Hall
Summary: This study aims to determine the effectiveness of Mulligan Manual Therapy (MMT) compared to placebo and exercise in managing migraine, tension-type headache, and cervicogenic headache. The pragmatic trial includes 297 participants with a primary outcome measure of headache frequency and secondary outcome measures such as headache duration, intensity, and medication intake.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Medicine, General & Internal
Francesco Amico, Sait Ashina, Eliot Parascandolo, Roni Sharon
Summary: This study investigated the impact of race and income on patients with migraine admitted to the hospital. The results showed that African American, Hispanic, and Native American patients were more likely to have lower household income, while Caucasian patients had higher income. However, race and income did not affect the length of hospital stay.
JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION
(2022)
Meeting Abstract
Clinical Neurology
Sait Ashina, Verena Ramirez Campos, Joshua Cohen, Lindsay Janka, Lynda Krasenbaum, Lydia Blume
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2022)
Article
Clinical Neurology
Sait Ashina, Lars Bendtsen, Rami Burstein, Afrim Iljazi, Rigmor Hoejland Jensen, Richard B. Lipton
Summary: This study investigated whether coexistent self-reported neck pain influences pain sensitivity in individuals with migraine and tension-type headache. The results showed that individuals with chronic headache had higher pericranial tenderness than controls, and this difference was more significant in individuals with neck pain. Coexistent neck pain was associated with greater pericranial tenderness in individuals with chronic headache and to a lesser degree in those with episodic headache.
SCANDINAVIAN JOURNAL OF PAIN
(2023)
Review
Clinical Neurology
Haidar Muhsen Al-Khazali, Sarra Al-Khazali, Afrim Iljazi, Rune Hackert Christensen, Sait Ashina, Richard Bruce Lipton, Faisal Mohammad Amin, Hakan Ashina
Summary: This study aims to estimate the relative frequencies and clinical features of hemicrania continua in adult patients with headache in a clinical setting. The meta-analysis of multiple studies found that the relative frequency of hemicrania continua was 1.8%, with the most common symptoms being lacrimation, conjunctival injection, and restlessness/agitation. The study highlights the need for standardized data acquisition and reporting to accurately determine the prevalence of hemicrania continua and increase awareness of its clinical importance.
Article
Medicine, General & Internal
Sait Ashina, Gisela M. M. Terwindt, Timothy J. J. Steiner, Mi Ji Lee, Frank Porreca, Cristina Tassorelli, Todd J. J. Schwedt, Rigmor H. H. Jensen, Hans-Christoph Diener, Richard B. B. Lipton
Summary: Medication overuse headache is a secondary headache disorder caused by excessive use of acute headache medications in individuals with an underlying headache disorder. This article reviews the epidemiology, pathophysiology, diagnosis and treatment of medication overuse headache, emphasizing the impact on patients' quality of life.
NATURE REVIEWS DISEASE PRIMERS
(2023)
Article
Psychology, Clinical
Agustin Melo-Carrillo, Raul Rodriguez, Sait Ashina, Brittany Lipinski, Paul Hart, Rami Burstein
Summary: The use of narrow band green light has been found to reduce anxiety symptoms in patients with generalized anxiety disorder (GAD). Therefore, it is suggested that incorporating narrow band green light into psychotherapy sessions may help alleviate anxiety in GAD patients.
PSYCHOLOGY RESEARCH AND BEHAVIOR MANAGEMENT
(2023)
Article
Clinical Neurology
Sait Ashina, Agustin Melo-Carrillo, Edina Szabo, David Borsook, Rami Burstein
Summary: This study used quantitative sensory testing to analyze the presence of cephalic and extracephalic allodynia in the pre-treatment non-ictal phase of migraine patients. The results showed that the presence of cephalic allodynia was highly correlated with the response to galcanezumab treatment, suggesting that it can be used to predict the treatment outcome.
Article
Rehabilitation
Haidar M. Al-Khazali, Lotte Skytte Kroll, Hakan Ashina, Agustin Melo-Carrillo, Rami Burstein, Faisal Mohammad Amin, Sait Ashina
Summary: Neck pain is a common complaint in the general population, often associated with primary headache disorders such as migraine and tension-type headache. There is a high prevalence of neck pain in people with migraine or tension-type headache, and it has been identified as a risk factor for these headaches. The exact mechanisms linking neck pain to migraine and tension-type headache are uncertain, but pain sensitivity appears to play a role.
MUSCULOSKELETAL SCIENCE AND PRACTICE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Li-Tzu Wang, Ping-Hao Chiang, Chi-Hsiang Chung, Mingyang Song, Sait Ashina, Wu-Chien Chien, Kevin Sheng-Kai Ma
Summary: This pilot study found a higher risk of head and neck cancers in patients with migraine, especially those with migraine with aura. Non-nasopharyngeal cancers were more commonly associated with migraine. Larger studies are needed to confirm these findings.
Review
Clinical Neurology
Dilara Onan, Samaira Younis, William David Wellsgatnik, Fatemeh Farham, Saulius Andruskevicius, Ana Abashidze, Asel Jusupova, Yuriy Romanenko, Oxana Grosu, Meerimgul Zamirbekovna Moldokulova, Ulkar Mursalova, Saida Saidkhodjaeva, Paolo Martelletti, Sait Ashina
Summary: This article explores the similarities and differences in the pathophysiology, epidemiology, burden and disability, comorbidities, and responses to treatments between tension-type headache (TTH) and migraine. Distinguishing between the two in clinical practice and research is challenging due to the lack of specific diagnostic tests and biomarkers. The article also discusses future research directions to address diagnostic challenges and improve the understanding and management of these conditions.
JOURNAL OF HEADACHE AND PAIN
(2023)
Article
Clinical Neurology
Sait Ashina, Agustin Melo-Carrillo, Ajayi Toluwanimi, Nicolas Bolo, Edina Szabo, David Borsook, Rami Burstein
Summary: This observational study demonstrates that prophylactic treatment with galcanezumab can significantly decrease the incidence of headache after exposure to triggers or aura episodes, and the presence of premonitory symptoms in treatment responders, non-responders, and super non-responders.
JOURNAL OF HEADACHE AND PAIN
(2023)
Article
Neuroimaging
Edina Szabo, Sait Ashina, Agustin Melo-Carrillo, Nicolas R. Bolo, David Borsook, Rami Burstein
Summary: Migraine is believed to be caused by neuroplastic changes in the central nervous system, which can be prevented by anti-CGRP-mAbs. A study found that treatment responders showed cortical thinning after 3 months of treatment, indicating changes in neural swelling and dendritic complexity due to reduction in head pain.
NEUROIMAGE-CLINICAL
(2023)
Meeting Abstract
Clinical Neurology
Peter J. Goadsby, Deborah I. Friedman, Dagny Holle-Lee, Genevieve Demarquay, Sait Ashina, Sung Y. Yu, Brett Dabruzzo, Hua Guo, Brittany Schwefel, Joel Trugman
Meeting Abstract
Clinical Neurology
S. Joshi, S. Ashina, T. Kurth, C. Vallarino, M. Vincent, R. L. Robinson
Meeting Abstract
Clinical Neurology
R. E. Shapiro, R. A. Nicholson, E. K. Seng, D. C. Buse, M. L. Reed, A. J. Zagar, S. Ashina, E. J. Muenzel, S. Hutchinson, E. M. Pearlman, R. B. Lipton
