Article
Orthopedics
Unni Moen, Mari Kalland Knapstad, Kjersti Thulin Wilhelmsen, Frederik Kragerud Goplen, Stein Helge Glad Nordahl, Jan Erik Berge, Bard Natvig, Dara Meldrum, Liv Heide Magnussen
Summary: Patients with long-term dizziness commonly experience widespread pain, which is associated with the severity of dizziness. It is recommended to assess and treat pain symptoms in patients with persistent dizziness.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Audiology & Speech-Language Pathology
Ryan J. Huang, Carl F. Pieper, Heather E. Whitson, Douglas B. Garrison, Juliessa M. Pavon, Kristal M. Riska
Summary: This study found no association between hearing loss and falls in patients with vestibular dysfunction or nonvestibular dizziness. Consistent with previous research, vestibular dysfunction and nonvestibular dizziness were independently associated with falls.
Article
Otorhinolaryngology
Emily C. Wong, Whitney Chiao, Blaze T. Strangio, Katrina Luong, Lauren Pasquesi, Isabel E. Allen, Jeffrey D. Sharon
Summary: Independent predictors for eeDHI scores include numbness in the face or body during dizziness, history of falls, female sex, caloric weakness, total number of diagnoses associated with dizziness, and total number of symptoms during dizziness. Patients with eeDHI have severe disease and should be screened for falls to alleviate disease related suffering.
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY
(2022)
Article
Geriatrics & Gerontology
Natalia Adamczewska, Samuel R. Nyman
Summary: The study provides a new theoretical understanding of the psychological response to falls in older adults, showing that falls efficacy is influenced by fear, dysphoria, and fear of falls. Dysphoria plays a central role in the constructs of falls efficacy and fear of falls, suggesting that fear of falls may not always be negative, but adaptive and protective.
AGING & MENTAL HEALTH
(2022)
Article
Clinical Neurology
Jingjing Wang, Shaojie Li, Yang Hu, Longbing Ren, Rui Yang, Yuling Jiang, Mingzhi Yu, Zhouwei Liu, Yifei Wu, Ziqi Dong, Chi Zhang, Wentian Dong, Yao Yao
Summary: This study found that falls and severe falls among older adults were positively associated with anxiety and depressive symptoms, and psychological resilience could moderate this association. These findings suggest that psychological resilience may be an effective target for intervention and prevention of fall-related symptoms of anxiety and depression.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Geriatrics & Gerontology
Louis Jacob, Karel Kostev, Jae Il Shin, Lee Smith, Hans Oh, Adel S. Abduljabbar, Josep Maria Haro, Ai Koyanagi
Summary: This study investigated the longitudinal association between falls and incident anxiety and depressive symptoms in adults aged ≥50 years living in Ireland. The study found that falls were significantly associated with anxiety and depressive symptoms, but these associations were no longer significant after including fear of falling in the models.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2023)
Article
Clinical Neurology
Sooyeon Min, Ji-Soo Kim, Hye Youn Park
Summary: The study found that females with PPPD had a better treatment response to SSRIs, and patients with higher initial disease severity also showed better responses. In men, younger age and lower anxiety levels were indicators for better outcomes, while absence of comorbidities was a predictor of better response in women.
JOURNAL OF NEUROLOGY
(2021)
Article
Geriatrics & Gerontology
Jasmin Krieger, Monika Frackowiak, Moritz Berger, Michael T. Heneka, Andreas H. Jacobs
Summary: One of the most important geriatric syndromes is dizziness accompanied by gait disorder and falls. Benign paroxysmal positional vertigo (BPPV) is one of the causes of dizziness, and targeted diagnosis and treatment can prevent falls and decline in quality of life, as well as unnecessary examinations and medication. A study found that diagnosing and treating BPPV in geriatric patients can reduce unnecessary examinations and medication, improve diagnostic accuracy, and prevent future falls.
EXPERIMENTAL GERONTOLOGY
(2022)
Article
Oncology
Xiangjie Chen, Jing Cheng, Jianrui Gong
Summary: The study demonstrates the clinical effectiveness of Deanxit in treating chronic subjective dizziness, showing significant improvement in dizziness symptoms, anxiety, and depression, as well as enhanced sleep quality and quality of life for patients.
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2021)
Review
Clinical Neurology
Soumyajit Das, Chandra Sekhar Annam, Satvinder Singh Bakshi, Ramesh Seepana
Summary: Persistent positional perceptual dizziness (PPPD) is a common cause of chronic dizziness and is often considered to be psychogenic. It is diagnosed based on clinical criteria and the vestibular function tests and imaging are usually normal. Most patients have anxiety traits and the condition often occurs after an acute vertigo attack. Vestibular sedatives do not have a role in the treatment, while vestibular rehabilitation therapy, cognitive behavioral therapy, and selective serotonin reuptake inhibitors may be beneficial. However, the long-term outcomes are still uncertain.
NEUROLOGICAL SCIENCES
(2023)
Article
Medicine, General & Internal
Yongchao Li, Bing Wu, Mao Li, Xiaodong Pang, Liang Yang, Chen Dai, Baogan Peng
Summary: This retrospective study aimed to explore the patient-reported outcome measures (PROM) following coblation nucleoplasty for cervical discogenic dizziness and to compare the therapeutic effect of coblation nucleoplasty with prolonged conservative treatment. The results showed that coblation nucleoplasty significantly improved the symptoms of dizziness and had superior efficacy compared to conservative treatment.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Geriatrics & Gerontology
Caterina Trevisan, Marianna Noale, Alessandra Imoscopi, Chiara Bigolaro, Cosetta Derni, Elena Agio, Sara Dal Ben, Marco Ceccato, Federica Tono, Stefania Maggi, Anna-Karin Welmer, Giuseppe Sergi
Summary: This prospective study evaluated the cognitive and physical trajectories of nursing home residents after falls and their predictors. It found that pre-fall cognitive function and some modifiable factors can impact the cognitive and physical health of residents after falls.
Article
Biochemistry & Molecular Biology
Maxim Devine, Canchen Ma, Jing Tian, Benny Antony, Flavia Cicuttini, Graeme Jones, Feng Pan
Summary: The study found that Class 1 and/or Class 2 had a higher risk of incident fractures and falls risk score than Class 3, highlighting the need for targeted preventive strategies to reduce the risk of fractures and falls in pain population.
Article
Public, Environmental & Occupational Health
Ramakrishna Kakara, Gwen Bergen, Elizabeth Burns, Mark Stevens
Summary: In the United States, unintentional falls are the leading cause of injury and injury death among adults aged >= 65 years. Patterns of nonfatal and fatal falls differ by sex and state. CDC recommends healthcare providers to screen and assess older adults for fall risk and intervene using effective preventive strategies.
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
(2023)
Article
Geriatrics & Gerontology
Rebekah Harris, Elsa S. Strotmeyer, Leena Sharma, C. Kent Kwoh, Jennifer S. Brach, Robert Boudreau, Jane A. Cauley
Summary: This study examined how the severity of radiographic knee osteoarthritis (KOA) affects recurrent falls in middle-aged and older individuals. The results showed that older adults with radiographic evidence of KOA had a higher likelihood of experiencing recurrent falls compared to those without KOA, regardless of established risk factors. On the other hand, middle-aged adults with KOA did not have an increased odds of recurrent falls, except for those with possible KOA.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Geriatrics & Gerontology
Meghan Ambrens, Melinda Stanners, Trinidad Valenzuela, Husna Razee, Jessica Chow, Kimberley S. van Schooten, Jaqueline C. T. Close, Lindy Clemson, G. A. Rixt Zijlstra, Stephen R. Lord, Anne Tiedemann, Stephanie J. Alley, Corneel Vandelanotte, Kim Delbaere
Summary: This study found that using digital technologies to deliver a fall prevention program is an effective and enjoyable method. Older adults are interested in learning how to engage successfully with novel technologies, although their experiences may vary. Despite some challenges, most participants were able to overcome difficulties and learn new skills. Understanding older adults' experiences with technology-driven methods is crucial for promoting and sustaining fall prevention programs.
JOURNAL OF GERIATRIC PHYSICAL THERAPY
(2023)
Review
Neurosciences
Lewis A. Ingram, Annie A. Butler, Stephen R. Lord, Simon C. Gandevia
Summary: Profiling performance in the physiological domains underpinning upper limb function provides insight into an individual's specific impairments. A battery of tests were used to create a core upper limb physiological profile assessment (PPA). Individual performance in each test can be compared to a reference population score, and a composite score provides an overview of overall upper limb function.
JOURNAL OF PHYSIOLOGY-LONDON
(2023)
Article
Geriatrics & Gerontology
Annabel P. P. Matison, Anbupalam Thalamuthu, Victoria M. M. Flood, Julian N. N. Trollor, Vibeke S. S. Catts, Margaret J. J. Wright, David Ames, Henry Brodaty, Perminder S. S. Sachdev, Simone Reppermund, Karen A. A. Mather
Summary: Previous research suggests that a higher intake of fruits and vegetables may protect against depression in older adults. This study aims to estimate the genetic and environmental influences on fruit and vegetable consumption in older adults, and explore the potential shared genetic influences on consumption and depression.
Article
Clinical Neurology
Jessica Gong, Katie Harris, Darren M. Lipnicki, Erico Castro-Costa, Maria Fernanda Lima-Costa, Breno S. Diniz, Shifu Xiao, Richard B. Lipton, Mindy J. Katz, Cuiling Wang, Pierre-Marie Preux, Maelenn Guerchet, Antoine Gbessemehlan, Karen Ritchie, Marie-Laure Ancelin, Ingmar Skoog, Jenna Najar, Therese Rydberg Sterner, Nikolaos Scarmeas, Mary Yannakoulia, Mary H. Kosmidis, Antonio Guaita, Elena Rolandi, Annalisa Davin, Oye Gureje, Stella Trompet, Jacobijn Gussekloo, Steffi Riedel-Heller, Alexander Pabst, Susanne Rohr, Suzana Shahar, Devinder Kaur Ajit Singh, Nurul Fatin Malek Rivan, Martin van Boxtel, Sebastian Kohler, Mary Ganguli, Chung-Chou Chang, Erin Jacobsen, Mary Haan, Ding Ding, Qianhua Zhao, Zhenxu Xiao, Kenji Narazaki, Tao Chen, Sanmei Chen, Tze Pin Ng, Xinyi Gwee, Katya Numbers, Karen A. Mather, Marcia Scazufca, Antonio Lobo, Concepcion De-la-Camara, Elena Lobo, Perminder S. Sachdev, Henry Brodaty, Maree L. Hackett, Sanne A. E. Peters, Mark Woodward
Summary: This meta-analysis of data from 21 cohorts across six continents found that women have a higher risk of developing dementia than men, especially in low- and lower-middle-income economies. Longer education and former alcohol use are stronger risk factors for dementia in men than in women, while other risk factors have similar effects in both genders.
ALZHEIMERS & DEMENTIA
(2023)
Article
Geriatrics & Gerontology
Maud Hevink, Claire Wolfs, Rudolf Ponds, Shelley Doucet, Carrie McAiney, Isabelle Vedel, Maria Mackowiak, Joanna Rymaszewska, Greta Rait, Louise Robinson, Marie Poole, Meredith Gresham, Yun-Hee Jeon, Lyn Phillipson, Lee-Fay Low, Henry Brodaty, Marjolein de Vugt, Frans Verhey
Summary: This study aims to describe the experiences of people with dementia and informal caregivers in receiving support after diagnosis, and compare these experiences. The study finds that there are differences in support experiences between satisfied and dissatisfied individuals.
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
(2023)
Article
Psychology, Clinical
Thanwarat Chantanachai, Daina L. Sturnieks, Stephen R. Lord, Jasmine Menant, Kim Delbaere, Perminder S. Sachdev, Henry Brodaty, Peter Humburg, Morag E. Taylor
Summary: This study examined longitudinal changes in cognitive and physical function, as well as the associations between these changes and falls in people with and without mild cognitive impairment (MCI). The results showed that the MCI and cognitively fluctuating groups experienced declines in cognitive function, while the cognitively normal group did not. The MCI group had worse physical function at baseline but similar decline over time compared to other groups. Decline in global cognitive function and sensorimotor performance were associated with multiple falls in the cognitively normal group, and decline in mobility was associated with falls in the entire sample. Therefore, exercise should be recommended for maintaining physical function in older adults, and interventions aimed at mitigating cognitive decline should be encouraged for people with MCI.
INTERNATIONAL PSYCHOGERIATRICS
(2023)
Article
Psychology, Clinical
Shafi Kalam, Katya Numbers, Darren M. Lipnicki, Ben C. P. Lam, Henry Brodaty, Simone Reppermund
Summary: This study investigated the associations between olfactory dysfunction and depression with dementia risk in older adults. The results showed that both factors independently predicted incident dementia over 12 years, and using both olfactory function testing and depression screening improved the ability to predict dementia.
INTERNATIONAL PSYCHOGERIATRICS
(2023)
Article
Geriatrics & Gerontology
Katya Numbers, Ben C. P. Lam, John D. Crawford, Nicole A. Kochan, Perminder S. Sachdev, Henry Brodaty
Summary: Individuals with subjective cognitive complaints (SCCs) are at an increased risk of dementia. Informant-reported SCCs appear to be more predictive of future dementia than participant-reported SCCs, and changes in both participants' and informants' SCCs over time are associated with dementia risk.
FRONTIERS IN AGING NEUROSCIENCE
(2023)
Article
Psychology, Clinical
Quoc C. C. Truong, Carol Choo, Katya Numbers, Adam Bentvelzen, Alexander G. G. Merkin, Henry Brodaty, Nicole A. A. Kochan, Valery L. L. Feigin, Perminder S. S. Sachdev, Oleg N. N. Medvedev
Summary: The study evaluated the psychometric properties of the TICS-M and used the Rasch methodology to improve its accuracy. The results showed good reliability of the TICS-M assessment scores, but there were some misfitting items and local dependency issues. By combining these problematic items into super-items, the Rasch model fit for the TICS-M improved, resulting in improved reliability and no misfitting or local dependency. The creation of a transformation table allows for converting raw TICS-M scores into interval-level data, increasing the precision of the instrument.
PSYCHOLOGICAL ASSESSMENT
(2023)
Article
Gerontology
Issra Allam, Meredith Gresham, Lyn Phillipson, Henry Brodaty, Lee-Fay Low
Summary: This study aims to understand the perceptions of dementia symptoms, help-seeking and support in the Australian Arabic-speaking community. By conducting qualitative interviews, seven themes were identified. Dementia was described as confusion and memory loss symptoms. Barriers to help-seeking and support included cultural norms, lack of knowledge on where to seek help, and fear of community judgement. Building trust through culturally appropriate support and educating the community are two ways to facilitate help-seeking and support.
DEMENTIA-INTERNATIONAL JOURNAL OF SOCIAL RESEARCH AND PRACTICE
(2023)
Article
Rehabilitation
Jacky Zheng, Meredith Gresham, Lyn Phillipson, Danika Hall, Yun-Hee Jeon, Henry Brodaty, Lee-Fay Low
Summary: This study examines the usability, usefulness, and user experience of the Forward with Dementia website for individuals with dementia and family caregivers. It also identifies strategies to improve web design for this population. The website was tested by 12 participants, and data collection involved observations, interviews, and questionnaires. Findings suggest that simplifying functions, streamlining navigation, and decluttering page layouts were effective strategies to improve the website's usability and user experience. The study highlights the importance of dementia-related websites in providing information and assistance to individuals managing dementia.
DISABILITY AND REHABILITATION-ASSISTIVE TECHNOLOGY
(2023)
Article
Psychology, Developmental
Princess Neila Litkouhi, Katya Numbers, Michael Valenzuela, John D. Crawford, Ben C. P. Lam, Princess Noosha Litkouhi, Perminder S. Sachdev, Nicole A. Kochan, Henry Brodaty
Summary: Cognitive, social, and physical activities, especially during young adulthood, are associated with better late-life cognitive outcomes. Formal education plays a significant role in the relationship between young adulthood cognitive activity and late-life global cognition.
AGING NEUROPSYCHOLOGY AND COGNITION
(2023)
Article
Orthopedics
N. Ramsay, J. C. T. Close, I. A. Harris, L. A. Harvey
Summary: Using cement in arthroplasty for hip fracture can improve postoperative function but may increase the risk of early mortality. This study found no significant association between cement use and mortality at 30 days and one year in patients with hip fracture. Therefore, cementing in arthroplasty for hip fracture can be considered a safe means of surgical fixation.
Article
Oncology
Daniel Steffens, Linda Denehy, Michael Solomon, Cherry Koh, Nabila Ansari, Kate McBride, Sharon Carey, Jenna Bartyn, Aaron Sean Lawrence, Kym Sheehan, Kim Delbaere
Summary: This study explores the perspectives of 30 gastrointestinal cancer patients on the adoption of a prehabilitation multimodal online program. Most patients recovering from gastrointestinal cancer surgery have a positive view on the safety and potential benefits of the online program. However, poor preoperative health, lack of motivation, and lack of personal encouragement are identified as the main barriers to its uptake.
