Journal
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
Volume 61, Issue 12, Pages 2174-2180Publisher
WILEY
DOI: 10.1111/jgs.12543
Keywords
function; activities of daily living; instrumental activities of daily living; cognitive screening; Mini-Mental State Examination; race; ethnicity; sex; sex differences
Categories
Funding
- National Institute on Aging [3P30AG031054-06S1]
- National Institutes of Health (NIH) [R01 AG16062, P30AG031054]
- NIH [R01 AG16062, P30AG031054, 5UL1 RR025777]
- NIH, National Center for Research Resources, Research Centers in Minority Institutions [G12-RR03034, U54 NS060659]
- Deep South Resource Center for Minority Aging Research
- Atlanta Regional Geriatric Educational Center Collaboration Allows for Enhanced Senior Care [UB4HP19215]
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ObjectivesTo examine the association between function measured according to activities of daily living (ADLs), instrumental activ1ities of daily living (IADLs), and cognition assessed according to Mini-Mental State Examination (MMSE) scores of older African-American and non-Hispanic white community-dwelling men and women. DesignCross-sectional study assessing associations between self-reported ADL and IADL difficulty and MMSE scores for race- and sex-specific groups. SettingHomes of community-dwelling older adults. ParticipantsA random sample of 974 African-American and non-Hispanic white Medicare beneficiaries aged 65 and older living in west-central Alabama and participating in the University of Alabama at Birmingham Study of Aging, excluding those with reported diagnoses of dementia or with missing data. MeasurementsFunction, based on self-reported difficulty in performing ADLs and IADLs, and cognition, using the MMSE. Multivariable linear regression models were used to test the association between function and cognition in race- and sex-specific groups after adjusting for covariates. ResultsMini-Mental State Examination scores were modestly correlated with ADL and IADL difficulty in all four race- and sex-specific groups, with Pearson correlation coefficients ranging from -0.189 for non-Hispanic white women to -0.429 for African-American men. Correlations between MMSE and ADL or IADL difficulty in any of the race- and sex-specific groups were no longer significant after controlling for sociodemographic factors and comorbidities. ConclusionMini-Mental State Examination was not significantly associated with functional difficulty in older African-American and non-Hispanic white men and women after adjusting for sociodemographic factors and comorbidities, suggesting a mediating role in the relationship between cognition and function.
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